Search Results - "BÜYÜKAFŞAR, Kansu"

Investigation of the anticancer effect of newly synthesized palladium conjugate Schiff base metal complexes on non-small cell lung cancer cell line and mouse embryonic fibroblast cell line by Demirbağ, Burcu, Büyükafşar, Kansu, Kaya, Hamide, Yıldırım, Metin, Bucak, Öznur, Ünver, Hakan, Erdoğan, Semra

“…Lung cancer remains one of the leading causes of death worldwide. Due to the side effects of chemotherapeutic agents on normal cells and the development of…”
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Effects of 17β-estradiol and progesterone on the production of adipokines in differentiating 3T3-L1 adipocytes: Role of Rho-kinase by Pektaş, Mehtap, Kurt, Akif Hakan, Ün, İsmail, Tiftik, Rukiye Nalan, Büyükafşar, Kansu

“…•17β-estradiol elevated resistin but decreased adiponectin and IL-6 levels.•Y-27632 inhibited the rise of resistin and fall of adiponectin by…”
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The effect of testosterone replacement therapy on bladder functions, histology, apoptosis, and Rho-kinase expression in bladder outlet obstruction and hypogonadism rat model by SAYLAM, Barış, EFESOY, Ozan, BOZDOĞAN ARPACI, Rabia, TİFTİK, Rukiye Nalan, TEK, Mesut, BÜYÜKAFŞAR, Kansu, BOZLU, Murat, ÇAYAN, Selahittin

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Rho/rho-kinase signalling in chronically alcohol-fed mice by Kubat, Havva, Yurtsever, Ahmet Sencer, Büyükafşar, Kansu

“…The effects of chronic ethanol consumption on male sexual function are debateable, and its effects on the Rho/Rho-kinase pathway are unknown. Therefore, we…”
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Hyperosmolar glucose induces vasoconstriction through Rho/Rho-kinase pathway in the rat aorta by Ün, İsmail, Kurt, A. Hakan, Büyükafşar, Kansu

“…Rho/Rho‐kinase signalling pathway plays a substantial role in vascular contractions. In this study, we investigated any roles of Rho/Rho‐kinase pathway in the…”
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Expression of Rho‐kinase (ROCK‐1 and ROCK‐2) and its substantial role in the contractile activity of the sheep ureter by Levent, Adnan, Büyükafşar, Kansu

“…Expression of two isoforms of Rho‐kinase (ROCK) and its functional role in the physiological control of smooth muscle contraction in the sheep ureter were…”
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Effects of the Rho-kinase inhibitors, Y-27632 and fasudil, on the corpus cavernosum from diabetic mice by Büyükafşar, Kansu, Un, Ismail

“…Relaxant responses to two Rho-kinase inhibitors, (+)-( R)- trans-4-(1-aminoethyl)- N-(4-pyridyl) cyclohexanecarboxamide dihydrochloride monohydrate (Y-27632)…”
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Expression of Rho‐kinase and its functional role in the contractile activity of the mouse vas deferens by Büyükafşar, Kansu, Levent, Adnan, Ark, Mustafa

“…The effects of two Rho‐kinase inhibitors, Y‐27632 and fasudil, were investigated on the contractions produced by electrical field stimulation (EFS, 40 V, 1 mS,…”
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The Role of Rho/Rho-Kinase Pathway in the Pathophysiology of Absence Epilepsy by Nihan ÇARÇAK, Melis YAVUZ, Tuğba ERYİĞİT, Akif Hakan KURT, Meral URHAN KÜÇÜK, Filiz ONAT, Kansu BÜYÜKAFŞAR

“…Objectives:Rho/Rho-kinase (ROCK) signaling has been shown to contribute to neuroinflammation, epileptogenesis, and seizures in convulsivetype epilepsy models…”
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The functional significance of the rho/rho-kinase pathway in human erythrocytes by Tiftik, R Nalan, Başkurt, Oğuz K, Kul, Seval, Büyükafşar, Kansu

“…Erythrocyte deformability, which can be influenced by various intracellular signaling mechanisms, such as nitric oxide, cAMP, cGMP, and protein kinases, is the…”
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Contribution of Rho-kinase in human gallbladder contractions by Büyükafşar, Kansu, Akça, Tamer, Nalan Tiftik, Rukiye, Şahan-Fırat, Seyhan, Aydın, Süha

“…Rho/Rho-kinase-mediated pathway has been involved in a variety of physiological processes, including Ca 2+ sensitization, which enhances smooth muscle…”
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Pharmacology of Botulinum Toxins: From Poison to Remedy by BÜYÜKAFŞAR, Kansu

“…Botulinum toxin (BTX) is produced by autolysis of several strains of Clostridium botulinum, a gram-positive, spore-forming, rod-shaped, strictly anaerobic…”
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Suppressive effect of Rho-kinase inhibitors Y-27632 and fasudil on spike-and-wave discharges in genetic absence epilepsy rats from Strasbourg (GAERS) by Çarçak, Nihan, Yavuz, Melis, Eryiğit Karamahmutoğlu, Tuğba, Kurt, Akif Hakan, Urhan Küçük, Meral, Onat, Filiz Yılmaz, Büyükafsar, Kansu

“…Rho/Rho-kinase (ROCK) signaling contributes to neuroinflammation, epileptogenesis, and seizures in convulsive-type epilepsies. However, this pathway has not…”
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Effects of the Rho/Rho-Kinase Pathway on Perfusion Pressure in the Isolated-Perfused Rat Hind Limb Vascular Bed by İlhan, Esra, Büyükafşar, Kansu, Tiftik, R Nalan, Seçilmiş, M Ata, Alzayed, Zayed

“…Rho/ROCK signaling has been demonstrated to be involved in the vascular reactivity of many arterial networks. However, RhoA expression and the contribution of…”
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Rho kinase expression and its central role in ovine gallbladder contractions elicited by a variety of excitatory stimuli by Şahan-Fırat, Seyhan, Tiftik, Rukiye Nalan, Nacak, Muradiye, Büyükafşar, Kansu

“…Rho kinase has contractile activity, which induces Ca 2+ sensitization in various cells. Several receptors are linked to the Rho/Rho-kinase pathway. Therefore,…”
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Rho-kinase (ROCK-1 and ROCK-2) upregulation in oleic acid-induced lung injury and its restoration by Y-27632 by Köksel, Oğuz, Yıldırım, Çağlar, Tiftik, Rukiye Nalan, Kubat, Havva, Tamer, Lülüfer, Cinel, Leyla, Kaplan, Murat Bayram, Değirmenci, Ulaş, Özdülger, Ali, Büyükafşar, Kansu

“…The possible contribution of Rho/Rho-kinase signalling in oleic acid (100 mg kg −1, i.v., for 4 h)-induced lung injury was investigated in rats. Furthermore,…”
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Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats by Büyükafşar, Kansu, Arıkan, Onur, Ark, Mustafa, Kubat, Havva, Özveren, Elif

“…Effects of bacterial lipopolysaccharide ( Escherichia coli serotype, 055:B5, 20 mg kg −1, i.p., for 6 h) and a Rho-kinase inhibitor, (+)-( R)-…”
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RhoA, ROCK-1, and ROCK-2 Gene Expression and Polymorphisms in Cholesteatoma Patients by Görür, Kemal, Büyükafşar, Kansu, Akbaş, Etem, İsmi, Onur, Yolal Ertural, Duygu, Çetinkaya, Ayşegül

“…The aim of this study was to evaluate the gene polymorphism and expressions of Rho-A, ROCK-1, and ROCK-2 in cholesteatoma. In this study, 120 healthy control…”
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Urocortin Induces Endothelium-Dependent Vasodilatation and Hyperpolarization of Rat Mesenteric Arteries by Activating Ca2+-Activated K+ Channels by Seçilmis, M. Ata, Özü, Özlem Yorulmaz, Emre, Mustafa, Büyükafsar, Kansu, Kiroglu, Olcay Ergürhan, Ertug, Peyman, Karatas, Yusuf, Önder, Serpil, Singirik, Ergin

“…Urocortin, a member of corticotropin releasing factor (CRF) peptide family, has positive chronotrophic and inotropic effects on heart and also shows a…”
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Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery by Ark, Mustafa, Ozveren, Elif, Yazici, Gürkan, Korkmaz, Belma, Büyükafsar, Kansu, Arikan, Onur, Kubat, Havva, Songu-Mize, Emel

“…A role for the small G protein rho and rho-kinase has been shown in smooth muscle contraction regarding Ca++ sensitivity. However, there are no data in the…”
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