Search Results - "BÖHNLEIN, E"

RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication by Bonyhadi, M L, Moss, K, Voytovich, A, Auten, J, Kalfoglou, C, Plavec, I, Forestell, S, Su, L, Böhnlein, E, Kaneshima, H

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High transdominant RevM10 protein levels are required to inhibit HIV-1 replication in cell lines and primary T cells : implication for gene therapy of AIDS by PLAVEC, I, AGARWAL, M, HO, K. E, PINEDA, M, AUTEN, J, BAKER, J, MATSUZAKI, H, ESCAICH, S, BONYHADI, M, BÖHNLEIN, E

“…Expression of antiviral genes in CD4+ T cells has been proposed as a strategy for gene therapy of AIDS. Over the past years, we and others have developed…”
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Tumor Necrosis Factor α Induces Proteins that Bind Specifically to κ B-Like Enhancer Elements and Regulate Interleukin 2 Receptor α -Chain Gene Expression in Primary Human T Lymphocytes by Lowenthal, John W., Ballard, Dean W., Böhnlein, Ernst, Greene, Warner C.

“…We have investigated the biochemical basis for the activation of interleukin 2 receptor α -subunit (IL-2Rα ) gene expression in primary human T lymphocytes by…”
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Inhibition of Human Immunodeficiency Virus Type 1 Replication in Human T Cells by Retroviral-Mediated Gene Transfer of a Dominant-Negative Rev Trans-Activator by Bevec, Dorian, Dobrovnik, Marika, Hauber, Joachim, Bohnlein, Ernst

“…Human immunodeficiency virus type 1 (HIV-1) is the causative agent of the acquired immunodeficiency syndrome (AIDS). Currently, no satisfactory treatment for…”
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The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV by Böhnlein, E, Lowenthal, J W, Siekevitz, M, Ballard, D W, Franza, B R, Greene, W C

“…Both the interleukin-2 receptor-alpha (Tac, p55, IL-2R alpha) gene and the long terminal repeat (LTR) of type 1 HIV are activated by various T cell mitogens…”
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Novel retroviral packaging cell lines : complementary tropisms and improved vector production for efficient gene transfer by FORESTELL, S. P, DANDO, J. S, CHEN, J, DE VRIES, P, BÖHNLEIN, E, RIGG, R. J

“…We report increased transduction of human hematopoietic progenitor cells through a combination of novel retroviral vector packaging cell lines, and improved…”
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Intracellular expression of RNA transcripts complementary to the human immunodeficiency virus type 1 gag gene inhibits viral replication in human CD4+ lymphocytes by Veres, G, Escaich, S, Baker, J, Barske, C, Kalfoglou, C, Ilves, H, Kaneshima, H, Böhnlein, E

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Definition of the human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex protein activation domain by functional exchange by Weichselbraun, I, Farrington, G K, Rusche, J R, Böhnlein, E, Hauber, J

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Scanning mutagenesis of the arginine-rich region of the human immunodeficiency virus type 1 Rev trans activator by Hammerschmid, M, Palmeri, D, Ruhl, M, Jaksche, H, Weichselbraun, I, Böhnlein, E, Malim, M H, Hauber, J

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Genetic instability of a MoMLV-based antisense double-copy retroviral vector designed for HIV-1 gene therapy by Junker, U, Böhnlein, E, Veres, G

“…We constructed a retroviral vector encoding a mutant tRNA(imet) gene followed by a HIV-1 rev-specific antisense sequence in the U3 region of the 3' long…”
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Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins by BÖHNLEIN, E, SIEKEVITZ, M, BALLARD, D. W, LOWENTHAL, J. W, RIMSKY, L, BOGERD, H, HOFFMAN, J, WANO, Y, FRANZA, B. R, GREENE, W. C

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Sustained retroviral gene marking and expression in lymphoid and myeloid cells derived from transduced hematopoietic progenitor cells by Plavec, I, Voytovich, A, Moss, K, Webster, D, Hanley, M B, Escaich, S, Ho, K E, Böhnlein, E, DiGiusto, D L

“…The expression of antiviral genes in human hematopoietic stem or progenitor cells has been proposed as a strategy for gene therapy of AIDS. To be successful,…”
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Regulation of Interleukin 2 Receptor α Subunit (Tac or CD25 Antigen) Gene Expression: Binding of Inducible Nuclear Proteins to Discrete Promoter Sequences Correlates with Transcriptional Activation by Lowenthal, John W., Böhnlein, Ernst, Ballard, Dean W., Greene, Warner C.

“…Transfection of deleted forms of the human interleukin 2 receptor α subunit (IL-2Rα ; also called CD25 or Tac antigen) gene (IL2RA) promoter revealed a…”
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Intracellular expression of human immunodeficiency virus type 1 (HIV-1) protease variants inhibits replication of wild-type and protease inhibitor-resistant HIV-1 strains in human T-cell lines by Junker, U, Escaich, S, Plavec, I, Baker, J, McPhee, F, Rose, J R, Craik, C S, Böhnlein, E

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RevM10-mediated inhibition of HIV-1 replication in chronically infected T cells by Escaich, S, Kalfoglou, C, Plavec, I, Kaushal, S, Mosca, J D, Böhnlein, E

“…Two clinical regimens have been proposed for gene therapies of acquired immunodeficiency syndrome (AIDS): (i) Genetic modification of differentiated peripheral…”
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Antiviral potency of drug-gene therapy combinations against human immunodeficiency virus type 1 by Junker, U, Baker, J, Kalfoglou, C S, Veres, G, Kaneshima, H, Böhnlein, E

“…Gene therapy for the treatment of human immunodeficiency virus type 1 (HIV-1) infection using intracellular immunization strategies is currently being tested…”
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Detection of intracellular HIV-1 Rev protein by flow cytometry by Rigg, R.J., Dando, J.S., Escaich, S., Plavec, I., Böhnlein, E.

“…The Rev trans-activator protein plays a pivotal role in human immunodeficiency virus type 1 (HIV-1) replication by allowing expression of the viral structural…”
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Functional analysis of human T-cell leukemia virus type I rex-response element: direct RNA binding of Rex protein correlates with in vivo activity by Ballaun, C, Farrington, G K, Dobrovnik, M, Rusche, J, Hauber, J, Boehnlein, E

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Mesenchymal stem cells as vehicles for gene delivery by Mosca, J D, Hendricks, J K, Buyaner, D, Davis-Sproul, J, Chuang, L C, Majumdar, M K, Chopra, R, Barry, F, Murphy, M, Thiede, M A, Junker, U, Rigg, R J, Forestell, S P, Böhnlein, E, Storb, R, Sandmaier, B M

“…Mesenchymal stem cells contribute to the regeneration of mesenchymal tissues such as bone, cartilage, muscle, ligament, tendon, adipose, and marrow stroma…”
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Hematopoietic Potential and Retroviral Transduction of CD34+Thy-1+ Peripheral Blood Stem Cells From Asymptomatic Human Immunodeficiency Virus Type-1–Infected Individuals Mobilized With Granulocyte Colony-Stimulating Factor by Junker, Uwe, Moon, James J., Kalfoglou, Creton S., Sniecinski, Irena, Forman, Stephen J., Zaia, John A., Kaneshima, Hideto, Böhnlein, Ernst

“…The potential of hematopoietic stem cells (HSCs) from human immunodeficiency virus type-1 (HIV-1)–infected individuals, eg, self-renewal and multilineage…”
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