Search Results - "BÄUMLER, Andreas J"
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Dysbiotic Proteobacteria expansion: a microbial signature of epithelial dysfunction
Published in Current opinion in microbiology (01-10-2017)“…[Display omitted] •Epithelial hypoxia drives anaerobiosis to maintain dominance of obligate anaerobes.•Increased epithelial oxygenation disrupts anaerobiosis…”
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The founder hypothesis: A basis for microbiota resistance, diversity in taxa carriage, and colonization resistance against pathogens
Published in PLoS pathogens (01-02-2019)“…[...]microbiota-accessible carbohydrates found in dietary fiber determine the abundance of fiber-consuming saccharolytic bacteria in the gut microbiota, and…”
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Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella
Published in Cell host & microbe (13-04-2016)“…The mammalian intestine is host to a microbial community that prevents pathogen expansion through unknown mechanisms, while antibiotic treatment can increase…”
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The microbiome and gut homeostasis
Published in Science (American Association for the Advancement of Science) (01-07-2022)“…Changes in the composition of the gut microbiota are associated with many human diseases. So far, however, we have failed to define homeostasis or dysbiosis by…”
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Evolution of the Chaperone/Usher Assembly Pathway: Fimbrial Classification Goes Greek
Published in Microbiology and Molecular Biology Reviews (01-12-2007)“…Article Usage Stats Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion
Published in Science (American Association for the Advancement of Science) (11-08-2017)“…Perturbation of the gut-associated microbial community may underlie many human illnesses, but the mechanisms that maintain homeostasis are poorly understood…”
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Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification
Published in The Journal of experimental medicine (07-01-2019)“…, , and other members of the Enterobacteriaceae family are common human pathogens that have acquired broad antibiotic resistance, rendering infection by some…”
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Commensal Enterobacteriaceae Protect against Salmonella Colonization through Oxygen Competition
Published in Cell host & microbe (09-01-2019)“…Neonates are highly susceptible to infection with enteric pathogens, but the underlying mechanisms are not resolved. We show that neonatal chick colonization…”
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High-fat diet-induced colonocyte dysfunction escalates microbiota-derived trimethylamine N -oxide
Published in Science (American Association for the Advancement of Science) (13-08-2021)“…A Western-style, high-fat diet promotes cardiovascular disease, in part because it is rich in choline, which is converted to trimethylamine (TMA) by the gut…”
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Respiration of Microbiota-Derived 1,2-propanediol Drives Salmonella Expansion during Colitis
Published in PLoS pathogens (01-01-2017)“…Intestinal inflammation caused by Salmonella enterica serovar Typhimurium increases the availability of electron acceptors that fuel a respiratory growth of…”
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The Pyromaniac Inside You: Salmonella Metabolism in the Host Gut
Published in Annual review of microbiology (15-10-2015)“…A metabolically diverse microbial community occupies all available nutrient-niches in the lumen of the mammalian intestine, making it difficult for pathogens…”
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The dynamics of gut-associated microbial communities during inflammation
Published in EMBO reports (01-04-2013)“…Our intestine is host to a large microbial community (microbiota) that educates the immune system and confers niche protection. Profiling of the gut‐associated…”
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Precision editing of the gut microbiota ameliorates colitis
Published in Nature (London) (11-01-2018)“…Tungstate inhibits molybdenum-cofactor-dependent microbial respiratory pathways and shows potential as a selective treatment for microbial imbalances that…”
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The impact of intestinal inflammation on the nutritional environment of the gut microbiota
Published in Immunology letters (01-12-2014)“…Highlights • Metal withholding mechanisms of the host alter the contest rules for microbes. • Exogenous electron acceptors are produced as a by-product of the…”
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Nitrate, nitrite and nitric oxide reductases: from the last universal common ancestor to modern bacterial pathogens
Published in Current opinion in microbiology (01-02-2016)“…Highlights • Bacterial cytochromes are conserved throughout evolution for the utilization of nitrogen oxides and oxygen. • These metalloproteins support…”
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High-Fat Diet and Antibiotics Cooperatively Impair Mitochondrial Bioenergetics to Trigger Dysbiosis that Exacerbates Pre-inflammatory Bowel Disease
Published in Cell host & microbe (12-08-2020)“…The clinical spectra of irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) intersect to form a scantily defined overlap syndrome, termed…”
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Virulence factors enhance Citrobacter rodentium expansion through aerobic respiration
Published in Science (American Association for the Advancement of Science) (16-09-2016)“…Citrobacter rodentium uses a type III secretion system (T3SS) to induce colonie crypt hyperplasia in mice, thereby gaining an edge during its competition with…”
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The Periplasmic Nitrate Reductase NapABC Supports Luminal Growth of Salmonella enterica Serovar Typhimurium during Colitis
Published in Infection and immunity (01-09-2015)“…The food-borne pathogen Salmonella enterica serovar Typhimurium benefits from acute inflammation in part by using host-derived nitrate to respire anaerobically…”
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Phase and Antigenic Variation in Bacteria
Published in Clinical Microbiology Reviews (01-07-2004)“…Classifications Services CMR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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5-Aminosalicylic Acid Ameliorates Colitis and Checks Dysbiotic Escherichia coli Expansion by Activating PPAR-γ Signaling in the Intestinal Epithelium
Published in mBio (19-01-2021)“…5-Aminosalicylic acid (5-ASA), a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, is a widely used first-line medication for the treatment of…”
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