Search Results - "Azzolini, Ana Elisa C. S."

Biological characterization of compounds from Rhinella schneideri poison that act on the complement system by Anjolette, Fernando A P, Leite, Flávia P, Bordon, Karla C F, Azzolini, Ana Elisa C S, Pereira, Juliana C, Pereira-Crott, Luciana S, Arantes, Eliane C

“…The skin secretions of toads of the family Bufonidae contain biogenic amines, alkaloids, steroids (bufotoxins), bufodienolides (bufogenin), peptides and…”
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Elastase Release by Stimulated Neutrophils Inhibited by Flavonoids: Importance of the Catechol Group by Kanashiro, Alexandre, Souza, Joel G., Kabeya, Luciana M., C. S. Azzolini, Ana Elisa, Lucisano-Valim, Yara Maria

“…Pathogenesis of chronic inflammatory diseases is associated with excessive elastase release through neutrophil degranulation. In the present study, inhibition…”
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Activation status of peripheral blood neutrophils and the complement system in adult rheumatoid arthritis patients undergoing combined therapy with infliximab and methotrexate by Marchi, Larissa F., Paoliello-Paschoalato, Adriana B., Oliveira, Renê D. R., Azzolini, Ana Elisa C. S., Kabeya, Luciana M., Donadi, Eduardo A., Lucisano-Valim, Yara Maria

“…We examined the functional activity of peripheral blood neutrophils and the complement system activation status in patients with rheumatoid arthritis (RA)…”
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Flavonols modulate the effector functions of healthy individuals' immune complex-stimulated neutrophils: A therapeutic perspective for rheumatoid arthritis by Santos, Everton O.L., Kabeya, Luciana M., Figueiredo-Rinhel, Andréa S.G., Marchi, Larissa F., Andrade, Micássio F., Piatesi, Fabiana, Paoliello-Paschoalato, Adriana B., Azzolini, Ana Elisa C.S., Lucisano-Valim, Yara M.

“…Rheumatoid arthritis (RA) patients usually exhibit immune complex (IC) deposition and increased neutrophil activation in the joint. In this study, we assessed…”
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Modulation of human neutrophil oxidative metabolism and degranulation by extract of Tamarindus indica L. fruit pulp by Paula, Fabiana S., Kabeya, Luciana M., Kanashiro, Alexandre, de Figueiredo, Andréa S.G., Azzolini, Ana Elisa C.S., Uyemura, Sérgio A., Lucisano-Valim, Yara Maria

“…The tamarind ( Tamarindus indica L .) is indigenous to Asian countries and widely cultivated in the American continents. The tamarind fruit pulp extract (ExT),…”
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Optimization of a flow cytometric assay to evaluate the human neutrophil ability to phagocytose immune complexes via Fcγ and complement receptors by Santos, Everton O.L., Azzolini, Ana Elisa C.S., Lucisano-Valim, Yara M.

“…This study aims to optimize some experimental conditions of a flow cytometric assay to examine the human neutrophil ability to phagocytose immune complexes…”
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Inhibition of immune complex-mediated neutrophil oxidative metabolism: A pharmacophore model for 3-phenylcoumarin derivatives using GRIND-based 3D-QSAR and 2D-QSAR procedures by Kabeya, Luciana M., da Silva, Carlos H.T.P., Kanashiro, Alexandre, Campos, Joaquín M., Azzolini, Ana Elisa C.S., Polizello, Ana Cristina M., Pupo, Mônica T., Lucisano-Valim, Yara M.

“…In this study, twenty hydroxylated and acetoxylated 3-phenylcoumarin derivatives were evaluated as inhibitors of immune complex-stimulated neutrophil oxidative…”
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Superoxide anion production by neutrophils is associated with prevalent clinical manifestations in systemic lupus erythematosus by Alves, Celene M. O. S., Marzocchi-Machado, Cleni M., Louzada-Junior, Paulo, Azzolini, Ana Elisa C. S., Polizello, Ana Cristina M., de Carvalho, Ivan F., Lucisano-Valim, Yara M.

“…To determine the relation between neutrophil function and the clinical characteristics of systemic lupus erythematosus (SLE), the superoxide anion ( )…”
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Effect of the extract of the tamarind ( Tamarindus indica) fruit on the complement system: Studies in vitro and in hamsters submitted to a cholesterol-enriched diet by Landi Librandi, Ana Paula, Chrysóstomo, Taís Nader, Azzolini, Ana Elisa C.S., Recchia, Carem Gledes Vargas, Uyemura, Sérgio Akira, de Assis-Pandochi, Ana Isabel

“…This work evaluated a crude hydroalcoholic extract (ExT) from the pulp of the tamarind ( Tamarindus indica) fruit as a source of compounds active on the…”
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Galectin-3 plays a modulatory role in the life span and activation of murine neutrophils during early Toxoplasma gondii infection by Alves, Celene M.O.S, Silva, Deise A.O, Azzolini, Ana Elisa C.S, Marzocchi-Machado, Cleni M, Carvalho, Julianne V, Pajuaba, Ana Cláudia A.M, Lucisano-Valim, Yara Maria, Chammas, Roger, Liu, Fu-Tong, Roque-Barreira, Maria C, Mineo, José R

“…Abstract Galectins are β-galactoside-binding lectins involved in several biological processes and galectin-3 (Gal-3) is related to modulation of immune and…”
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Neutrophil effector functions triggered by Fc-gamma and/or complement receptors are dependent on B-ring hydroxylation pattern and physicochemical properties of flavonols by Moreira, Mirian R., Kanashiro, Alexandre, Kabeya, Luciana M., Polizello, Ana Cristina M., Azzolini, Ana Elisa C.S., Curti, Carlos, Oliveira, Carlos A., T.-do Amaral, Antonia, Lucisano-Valim, Yara M.

“…Tissue damage in autoimmune diseases involves excessive production of reactive oxygen species (ROS) triggered by immune complexes (IC) and neutrophil (PMN)…”
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Galectin-1 modulation of neutrophil reactive oxygen species production depends on the cell activation state by Rodrigues, Lílian C., Kabeya, Luciana M., Azzolini, Ana Elisa C.S., Cerri, Daniel Giuliano, Stowell, Sean R., Cummings, Richard D., Lucisano-Valim, Yara Maria, Dias-Baruffi, Marcelo

“…•Galectin-1 up- or downmodulates neutrophil ROS production, depending on the cell activation state.•The carbohydrate-binding activity of galectin-1 is required…”
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The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3′,4′-methylenedioxyphenyl]-coumarin downmodulates the FcγR- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation and release of neutrophil extracellular traps by Andrade, Micássio F., Kabeya, Luciana M., Bortot, Leandro O., dos Santos, Gabriela B., Santos, Everton O.L., Albiero, Lucinéia R., Figueiredo-Rinhel, Andréa S.G., Carvalho, Camila A., Azzolini, Ana Elisa C.S., Caliri, Antonio, Pupo, Mônica T., Emery, Flavio S., Lucisano-Valim, Yara Maria

“…In this study, we report the ability of a set of eight 3-phenylcoumarin derivatives bearing 6,7- or 5,7-dihydroxyl groups, free or acetylated, bound to the…”
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Baccharis dracunculifolia DC (Asteraceae) selectively modulates the effector functions of human neutrophils by Figueiredo‐Rinhel, Andréa S. G., Melo, Lamartine L., Bortot, Leandro O., Santos, Everton O. L., Andrade, Micássio F., Azzolini, Ana Elisa C. S., Kabeya, Luciana M., Caliri, Antonio, Bastos, Jairo K., Lucisano‐Valim, Yara Maria

“…Objectives To examine whether the hydroalcoholic extract from Baccharis dracunculifolia leaves (BdE) modulates the human neutrophil oxidative metabolism,…”
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3,3′,5,5′-Tetramethylbenzidine in hypochlorous acid and taurine chloramine scavenging assays: interference of dimethyl sulfoxide and other vehicles by Kabeya, Luciana M., Andrade, Micássio F., Piatesi, Fabiana, Azzolini, Ana Elisa C.S., Polizello, Ana Cristina M., Lucisano-Valim, Yara Maria

“…This article shows how six vehicles interfere in the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by hypochlorous acid (HOCl) and taurine chloramine in…”
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7-Hydroxycoumarin modulates the oxidative metabolism, degranulation and microbial killing of human neutrophils by Kabeya, Luciana M., Fuzissaki, Carolina N., Taleb-Contini, Silvia H., da C. Ferreira, Ana Maria, Naal, Zeki, Santos, Everton O.L., Figueiredo-Rinhel, Andréa S.G., Azzolini, Ana Elisa C.S., Vermelho, Roberta B., Malvezzi, Alberto, -do Amaral, Antonia T., Lopes, João Luis C., Lucisano-Valim, Yara Maria

“…•7-Hydroxycoumarin derivatives modulate the oxidative metabolism of human neutrophils.•7-Hydroxycoumarin impairs degranulation of neutrophils and killing of…”
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The Flavonols Quercetin, Myricetin, Kaempferol, and Galangin Inhibit the Net Oxygen Consumption by Immune Complex- Stimulated Human and Rabbit Neutrophils by Figueiredo-Rinhel, Andréa S. G., Santos, Everton O. L., Kabeya, Luciana M., Azzolini, Ana Elisa C. S., Simões-Ambrosio, Livia M. C., Lucisano-Valim, Yara M

“…Stimulated human neutrophils exhibit increased net oxygen consumption (NOC) due to the conversion of O into the superoxide anion by the NADPH oxidase enzymatic…”
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3-Phenylcoumarin derivatives selectively modulate different steps of reactive oxygen species production by immune complex-stimulated human neutrophils by Andrade, Micássio F., Kabeya, Luciana M., Azzolini, Ana Elisa C.S., Santos, Everton O.L., Figueiredo-Rinhel, Andréa S.G., Paris, Márcio R.P., Emery, Flávio S., Pupo, Mônica T., Lucisano-Valim, Yara M.

“…Immune complex (IC) deposition in tissues triggers the release of harmful oxidant and lytic compounds by neutrophils. We examined how ten 3-phenylcoumarin…”
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4-methylcoumarin derivatives inhibit human neutrophil oxidative metabolism and elastase activity by Kabeya, Luciana M, Fuzissaki, Carolina N, Andrade, Micássio F, Azzolini, Ana Elisa C S, Taleb-Contini, Silvia H, Vermelho, Roberta B, Lopes, João Luis C, Lucisano-Valim, Yara Maria

“…Increased neutrophil activation significantly contributes to the tissue damage in inflammatory illnesses; this phenomenon has motivated the search for new…”
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Ethanolic Crude Extract and Flavonoids Isolated from Alternanthera maritima: Neutrophil Chemiluminescence Inhibition and Free Radical Scavenging Activity by Souza, Joel G., Tomei, Rafael R., Kanashiro, Alexandre, Kabeya, Luciana M., Azzolini, Ana Elisa C. S., Dias, Diones A., Salvador, Marcos J., Lucisano-Valim, Yara M.

“…Extracts from Alternanthera maritima are used in Brazilian folk medicine for the treatment of infectious and inflammatory diseases. Bioassay-guided…”
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