Search Results - "Azzegagh, Zoulikha"

β2-Adrenoceptor agonists are required for development of the asthma phenotype in a murine model by Thanawala, Vaidehi J, Forkuo, Gloria S, Al-Sawalha, Nour, Azzegagh, Zoulikha, Nguyen, Long P, Eriksen, Jason L, Tuvim, Michael J, Lowder, Thomas W, Dickey, Burton F, Knoll, Brian J, Walker, Julia K L, Bond, Richard A

“…β(2)-Adrenoceptor (β2AR) agonists are the most effective class of bronchodilators and a mainstay of asthma management. The first potent β2AR agonist discovered…”
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Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells by Kim, Kyubo, Petrova, Youlia M, Scott, Brenton L, Nigam, Rupesh, Agrawal, Anurag, Evans, Christopher M, Azzegagh, Zoulikha, Gomez, Alejandra, Rodarte, Elsa M, Olkkonen, Vesa M, Bagirzadeh, Rustam, Piccotti, Lucia, Ren, Binhui, Yoon, Joo-Heon, McNew, James A, Adachi, Roberto, Tuvim, Michael J, Dickey, Burton F

“…Airway mucin secretion and MC (mast cell) degranulation must be tightly controlled for homoeostasis of the lungs and immune system respectively. We found the…”
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SNAP23 is selectively expressed in airway secretory cells and mediates baseline and stimulated mucin secretion by Ren, Binhui, Azzegagh, Zoulikha, Jaramillo, Ana M, Zhu, Yunxiang, Pardo-Saganta, Ana, Bagirzadeh, Rustam, Flores, Jose R, Han, Wei, Tang, Yong-Jun, Tu, Jing, Alanis, Denise M, Evans, Christopher M, Guindani, Michele, Roche, Paul A, Rajagopal, Jayaraj, Chen, Jichao, Davis, C William, Tuvim, Michael J, Dickey, Burton F

“…Airway mucin secretion is important pathophysiologically and as a model of polarized epithelial regulated exocytosis. We find the trafficking protein, SNAP23…”
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Airway Mucin Secretion by Jaramillo, Ana M, Azzegagh, Zoulikha, Tuvim, Michael J, Dickey, Burton F

“…Exocytosis of secreted mucins is the final step in their intracellular processing, resulting in their release into the airway lumen to interact with water and…”
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Abstract 3714: Muc5ac plays an essential role in promotion of k-ras mutant lung cancer by Umer, Misha, Cumpian, Amber M., Khosravi, Nasim, Azzegagh, Zoulikha, Mohebnasab, Maede, Caetano, Mauricio S., Ostrin, Edwin J., Wistuba, Ignacio I., Dickey, Burton, Kadara, Humam, Evans, Christopher M., Moghaddam, Seyed J.

“…Abstract Worldwide, lung cancer is the leading cause of cancer mortality, and cigarette smoking (CS) is its principal cause. However, several studies have…”
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Requirement for MUC5AC in KRAS-dependent lung carcinogenesis by Bauer, Alison K, Umer, Misha, Richardson, Vanessa L, Cumpian, Amber M, Harder, Anna Q, Khosravi, Nasim, Azzegagh, Zoulikha, Hara, Naoko M, Ehre, Camille, Mohebnasab, Maedeh, Caetano, Mauricio S, Merrick, Daniel T, van Bokhoven, Adrie, Wistuba, Ignacio I, Kadara, Humam, Dickey, Burton F, Velmurugan, Kalpana, Mann, Patrick R, Lu, Xian, Barón, Anna E, Evans, Christopher M, Moghaddam, Seyed Javad

“…With more than 150,000 deaths per year in the US alone, lung cancer has the highest number of deaths for any cancer. These poor outcomes reflect a lack of…”
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Different Munc18 proteins mediate baseline and stimulated airway mucin secretion by Jaramillo, Ana M, Piccotti, Lucia, Velasco, Walter V, Delgado, Anna Sofia Huerta, Azzegagh, Zoulikha, Chung, Felicity, Nazeer, Usman, Farooq, Junaid, Brenner, Josh, Parker-Thornburg, Jan, Scott, Brenton L, Evans, Christopher M, Adachi, Roberto, Burns, Alan R, Kreda, Silvia M, Tuvim, Michael J, Dickey, Burton F

“…Airway mucin secretion is necessary for ciliary clearance of inhaled particles and pathogens but can be detrimental in pathologies such as asthma and cystic…”
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β 2 -Adrenoceptor Agonists Are Required for Development of the Asthma Phenotype in a Murine Model by Thanawala, Vaidehi J., Forkuo, Gloria S., Al-Sawalha, Nour, Azzegagh, Zoulikha, Nguyen, Long P., Eriksen, Jason L., Tuvim, Michael J., Lowder, Thomas W., Dickey, Burton F., Knoll, Brian J., Walker, Julia K. L., Bond, Richard A.

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[Beta]2-Adrenoceptor Agonists Are Required for Development of the Asthma Phenotype in a Murine Model by Thanawala, Vaidehi J, kuo, Gloria S, Al-Sawalha, Nour, Azzegagh, Zoulikha, Nguyen, Long P, Eriksen, Jason L, Tuvim, Michael J, Lowder, Thomas W, Dickey, Burton F, Knoll, Brian J, Walker, Julia K L, Bond, Richard A

“…[beta](2)-Adrenoceptor ([beta]2AR) agonists are the most effective class of bronchodilators and a mainstay of asthma management. The first potent [beta]2AR…”
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