Search Results - "Azuma, J."

Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study by Nishimoto, N, Miyasaka, N, Yamamoto, K, Kawai, S, Takeuchi, T, Azuma, J

“…To evaluate the safety and efficacy of 5-year, long-term tocilizumab monotherapy for patients with rheumatoid arthritis. In an open-label, long-term extension…”
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Microwave-Assisted Autohydrolysis of Prunus mume Stone for Extraction of Polysaccharides and Phenolic Compounds by Tsubaki, S, Ozaki, Y, Azuma, J

“…Stone of Prunus mume (P. mume) is a by-product of pickled P. mume industry. Stones of native and pickled P. mume, mainly composed of holocellulose (83.8 ± 1.8%…”
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Properties of bacterial cellulose transparent film regenerated from dimethylacetamide-LiCl solution by Yudianti, R., Syampurwadi, A., Onggo, H., Karina, M., Uyama, H., Azuma, J.

“…Excellent transparent films were prepared from bacterial cellulose (BC) sheets by solubilization of its defibrillated freeze‐dried specimens in a solvent of…”
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Differential Role of Symbiotic Fungi in Lignin Degradation and Food Provision for Fungus-Growing Termites (Macrotermitinae: Isoptera) by Hyodo, F., Tayasu, I., Inoue, T., J.-I. Azuma, Kudo, T., Abe, T.

“…1. To investigate whether the role of symbiotic fungi in lignin degradation and food provision differs among fungus-growing termites (four species of…”
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Dual cellulose-digesting system of the wood-feeding termite, Coptotermes formosanus Shiraki by Nakashima, K, Watanabe, H, Saitoh, H, Tokuda, G, Azuma, J.-I

“…The distribution of endo-β-1,4-glucanase (EG) components in the digestive system of the wood-feeding termite, Coptotermes formosanus Shiraki, was investigated…”
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Pharmacokinetics/Genotype Associations for Major Cytochrome P450 Enzymes in Native and First- and Third-generation Japanese Populations: Comparison With Korean, Chinese, and Caucasian Populations by Myrand, SP, Sekiguchi, K, Man, MZ, Lin, X, Tzeng, R‐Y, Teng, C‐H, Hee, B, Garrett, M, Kikkawa, H, Lin, C‐Y, Eddy, SM, Dostalik, J, Mount, J, Azuma, J, Fujio, Y, Jang, I‐J, Shin, S‐G, Bleavins, MR, Williams, JA, Paulauskis, JD, Wilner, KD

“…Application of foreign clinical data across geographic regions can accelerate drug development. Drug disposition can be variable, and identification of factors…”
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Cellulase genes from the parabasalian symbiont Pseudotrichonympha grassii in the hindgut of the wood-feeding termite Coptotermes formosanus by Nakashima, K I, Watanabe, H, Azuma, J I

“…Cellulase genes of Pseudotrichonympha grassii (Hypermastigida: Eucomonymphidae), the symbiotic flagellate in the hindgut of the wood-feeding termite…”
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Role of osmoregulation in the actions of taurine by Schaffer, S, Takahashi, K, Azuma, J

“…Taurine regulates an unusual number of biological phenomena, including heart rhythm, contractile function, blood pressure, platelet aggregation, neuronal…”
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Pharmacokinetics, Safety, and Tolerability of Atomoxetine and Effect of CYP2D610/10 Genotype in Healthy Japanese Men by Matsui, A., Azuma, J., Witcher, J. W., Long, A. J., Sauer, J.-M., Smith, B. P., DeSante, K. A., Read, H. A., Takahashi, M., Nakano, M.

“…Atomoxetine is a cytochrome P4502D6 (CYP2D6) substrate. The reduced-activity CYP2D6*10 allele is particularly prevalent in the Japanese population and may…”
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STAT3 mediates cardioprotection against ischemia/reperfusion injury through metallothionein induction in the heart by OSHIMA, Yuichi, FUJIO, Yasushi, NAKANISHI, Tsuyoshi, ITOH, Norio, YAMAMOTO, Yasuhiro, NEGORO, Shinji, TANAKA, Keiichi, KISHIMOTO, Tadamitsu, KAWASE, Ichiro, AZUMA, Junichi

“…Activation of signal transducer and activator of transcription 3 (STAT3) was reported to be correlated with myocardial protection against ischemia/reperfusion…”
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Genetic variants in combination with early partial improvement as a clinical utility predictor of treatment outcome in major depressive disorder: the result of two pooled RCTs by Kato, M, Serretti, A, Nonen, S, Takekita, Y, Wakeno, M, Azuma, J, Kinoshita, T

“…Pharmacogenetics may allow for a personalized treatment, but a combination with clinical variables may further enhance prediction. In particular, in the…”
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Occupied and unoccupied electronic structures of an L-cysteine film studied by core-absorption and resonant photoelectron spectroscopies by Kamada, M., Hideshima, T., Azuma, J., Yamamoto, I., Imamura, M., Takahashi, K.

“…Unoccupied and occupied electronic structures of an L-cysteine film have been studied by absorption and resonant photoelectron spectroscopies. Core absorptions…”
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Angiogenic and antifibrotic actions of hepatocyte growth factor improve cardiac dysfunction in porcine ischemic cardiomyopathy by AZUMA, J, TANIYAMA, Y, TAKEYA, Y, IEKUSHI, K, AOKI, M, DOSAKA, N, MATSUMOTO, K, NAKAMURA, T, OGIHARA, T, MORISHITA, R

“…Impairment of cardiac function in ischemic cardiomyopathy has been postulated to be due to the decrease in blood flow and increase in collagen synthesis…”
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P.2.f.002 Effect of brain volume-related single nucleotide polymorphisms (SNPs) of glycogen synthase kinase 3 (GSK3)-beta gene on SSRI/SNRI treatment response in major depressive disorder by Kato, M, Nonen, S, Takekita, Y, Azuma, J, Kinoshita, T

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Role of the mutualistic fungus in lignin degradation in the fungus-growing termite Macrotermes gilvus (Isoptera; Macrotermitinae) by Hyodo, F, Inoue, T, Azuma, J.-I, Tayasu, I, Abe, T

“…In order to investigate the role of the mutualistic fungus, Termitomyces sp., in the fungus-growing termite, Macrotermes gilvus, we applied CP/MAS 13C NMR and…”
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Cellulose and xylan utilisation in the lower termite Reticulitermes speratus by Inoue, T, Murashima, K, Azuma, J.I, Sugimoto, A, Slaytor, M

“…The distribution of the enzymes of cellulose and xylan metabolism namely endo-beta-1,4-glucanase, beta-glucosidase, endo-beta-1,4-xylanase and beta-xylosidase…”
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Two Chains of Rhamnogalacturonan II Are Cross-Linked by Borate-Diol Ester Bonds in Higher Plant Cell Walls by KOBAYASHI, M, MATOH, T, AZUMA, J.-I

“…Polysaccharide moiety of the boron-polysaccharide complex (T. Matoh, K. Ishigaki, K. Ohno, J. Azuma [1993] Plant Cell Physiol 34: 639-642) isolated from radish…”
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Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicin-induced hepatotoxicity by OHNO, M, YAMAGUCHI, I, KOMUTA, K, IGARASHI, T, AZUMA, J, YAMAMOTO, I, FUKUDA, T, YOKOTA, S, MAEKURA, R, ITO, M, YAMAMOTO, Y, OGURA, T, MAEDA, K

“…SETTING: Japanese in-patients with pulmonary tuberculosis and normal liver function receiving treatment with isoniazid and rifampicin (INH + RMP).OBJECTIVE: To…”
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P.3.d.018 Effect of the DRD2 polymorphisms on perospirone and aripiprazole efficacy for Japanese schizophrenia patients – Results of an RCT by Takekita, Y, Kato, M, Nonen, S, Wakeno, M, Sakai, S, Okugawa, G, Azuma, J, Kinoshita, T

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CYP2A6 polymorphisms are associated with nicotine dependence and influence withdrawal symptoms in smoking cessation by Kubota, T, Nakajima-Taniguchi, C, Fukuda, T, Funamoto, M, Maeda, M, Tange, E, Ueki, R, Kawashima, K, Hara, H, Fujio, Y, Azuma, J

“…CYP2A6 is the main enzyme that catalyzes nicotine into cotinine. Interindividual differences in nicotine metabolism result at least partially from polymorphic…”
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