Search Results - "Aznar, María Angela"
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Downregulation of FOXP1 is required during germinal center B-cell function
Published in Blood (23-05-2013)“…B-cell maturation and germinal center (GC) formation are dependent on the interplay between BCL6 and other transcriptional regulators. FOXP1 is a transcription…”
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For Whom the Cell Tolls? Intratumoral Treatment Links Innate and Adaptive Immunity
Published in Clinical cancer research (15-02-2019)“…Intratumoral immunotherapy can potentially modulate the tumor microenvironment (TME) and potentiate the effects of concomitant or sequential systemic…”
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Edelfosine Lipid Nanoparticles Overcome Multidrug Resistance in K‑562 Leukemia Cells by a Caspase-Independent Mechanism
Published in Molecular pharmaceutics (04-08-2014)“…The antitumor ether lipid edelfosine is the prototype of a novel generation of promising anticancer drugs that has been shown to be an effective antitumor…”
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LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome
Published in Haematologica (Roma) (01-07-2011)“…LMO2 is highly expressed at the most immature stages of lymphopoiesis. In T-lymphocytes, aberrant LMO2 expression beyond those stages leads to T-cell acute…”
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Repurposing the yellow fever vaccine for intratumoral immunotherapy
Published in EMBO molecular medicine (09-01-2020)“…Live 17D is widely used as a prophylactic vaccine strain for yellow fever virus that induces potent neutralizing humoral and cellular immunity against the…”
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Efficacy of edelfosine lipid nanoparticles in breast cancer cells
Published in International journal of pharmaceutics (01-10-2013)“…Breast cancer is a heterogeneous group of neoplasms predominantly originating in the terminal duct lobular units. It represents the leading cause of cancer…”
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International Symposium: Trailblazing in Cancer Immunotherapy, October 29–31, 2017, Pamplona, Spain
Published in Cancer Immunology, Immunotherapy (01-11-2018)Get full text
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Mitochondrial Morphological and Functional Reprogramming Following CD137 (4-1BB) Costimulation
Published in Cancer immunology research (01-07-2018)“…T and NK lymphocytes express CD137 (4-1BB), a costimulatory receptor of the TNFR family whose function is exploitable for cancer immunotherapy. Mitochondria…”
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Lipid nanoparticles protect from edelfosine toxicity in vivo
Published in International journal of pharmaceutics (20-10-2014)“…[Display omitted] Edelfosine, an alkyl-lysophospholipid antitumor drug with severe side-effects, has previously been encapsulated into lipid nanoparticles (LN)…”
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