Search Results - "Aznar, Arantxa Ortega"

Proinsulin protects against age-related cognitive loss through anti-inflammatory convergent pathways by Corpas, Rubén, Hernández-Pinto, Alberto M., Porquet, David, Hernández-Sánchez, Catalina, Bosch, Fatima, Ortega-Aznar, Arantxa, Comellas, Francesc, de la Rosa, Enrique J., Sanfeliu, Coral

“…Brain inflammaging is increasingly considered as contributing to age-related cognitive loss and neurodegeneration. Despite intensive research in multiple…”
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MMP-2/MMP-9 Plasma Level and Brain Expression in Cerebral Amyloid Angiopathy-Associated Hemorrhagic Stroke by Hernandez-Guillamon, Mar, Martinez-Saez, Elena, Delgado, Pilar, Domingues-Montanari, Sophie, Boada, Cristina, Penalba, Anna, Boada, Mercè, Pagola, Jorge, Maisterra, Olga, Rodriguez-Luna, David, Molina, Carlos A., Rovira, Alex, Alvarez-Sabin, José, Ortega-Aznar, Arantxa, Montaner, Joan

“…Cerebral amyloid angiopathy (CAA) is one of the main causes of intracerebral hemorrhage (ICH) in the elderly. Matrix metalloproteinases (MMPs) have been…”
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peIF4E as an independent prognostic factor and a potential therapeutic target in diffuse infiltrating astrocytomas by Martínez‐Sáez, Elena, Peg, Vicente, Ortega‐Aznar, Arantxa, Martínez‐Ricarte, Francisco, Camacho, Jessica, Hernández‐Losa, Javier, Ferreres Piñas, Joan Carles, Ramón y Cajal, Santiago

“…Malignant transformation in tumors is a complex process requiring accumulation of numerous oncogenic abnormalities. Brain tumors show considerable phenotypic…”
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MMP-9-Positive Neutrophil Infiltration Is Associated to Blood-Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke by ROSELL, Anna, CUADRADO, Eloy, ORTEGA-AZNAR, Arantxa, HERNANDEZ-GUILLAMON, Mar, LO, Eng H, MONTANER, Joan

“…An abnormal expression of some matrix metalloproteinases (MMPs) is related with hemorrhagic transformation events after stroke. Our aim was to investigate…”
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Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke by ROSELL, Anna, ORTEGA-AZNAR, Arantxa, ALVAREZ-SABIN, José, FERNANDEZ-CADENAS, Israel, RIBO, Marc, MOLINA, Carlos A, LO, Eng H, MONTANER, Joan

“…Abnormal expression of some matrix metalloproteinases (MMP) has shown to play a deleterious role in brain injury in experimental models of cerebral ischemia…”
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In vivo evaluation of amyloid deposition and brain glucose metabolism of 5XFAD mice using positron emission tomography by Rojas, Santiago, Herance, José Raúl, Gispert, Juan Domingo, Abad, Sergio, Torrent, Élia, Jiménez, Xavier, Pareto, Deborah, Perpiña, Unai, Sarroca, Sara, Rodríguez, Elisenda, Ortega-Aznar, Arantxa, Sanfeliu, Coral

“…Abstract Positron emission tomography (PET) has been used extensively to evaluate the neuropathology of Alzheimer's disease (AD) in vivo. Radiotracers directed…”
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Vascular MMP-9/TIMP-2 and Neuronal MMP-10 Up-Regulation in Human Brain after Stroke: A Combined Laser Microdissection and Protein Array Study by Cuadrado, Eloy, Rosell, Anna, Penalba, Anna, Slevin, Mark, Alvarez-Sabín, José, Ortega-Aznar, Arantxa, Montaner, Joan

“…Matrix Metalloproteinases (MMPs) play an important role in brain injury after ischemic stroke. In the present study, we aimed to assess the global expression…”
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Brain perihematoma genomic profile following spontaneous human intracerebral hemorrhage by Rosell, Anna, Vilalta, Anna, García-Berrocoso, Teresa, Fernández-Cadenas, Israel, Domingues-Montanari, Sophie, Cuadrado, Eloy, Delgado, Pilar, Ribó, Marc, Martínez-Sáez, Elena, Ortega-Aznar, Arantxa, Montaner, Joan

“…Spontaneous intracerebral hemorrhage (ICH) represents about 15% of all strokes and is associated with high mortality rates. Our aim was to identify the gene…”
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Matrix metalloproteinase-13 is activated and is found in the nucleus of neural cells after cerebral ischemia by Cuadrado, Eloy, Rosell, Anna, Borrell-Pagès, Maria, García-Bonilla, Lidia, Hernández-Guillamon, Mar, Ortega-Aznar, Arantxa, Montaner, Joan

“…Matrix metalloproteinases (MMPs) have been implicated in the pathophysiology of ischemic stroke. In this study, we investigated the time course of…”
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In vitro and in vivo activation of astrocytes by amyloid-beta is potentiated by pro-oxidant agents by García-Matas, Silvia, de Vera, Núria, Aznar, Arantxa Ortega, Marimon, Josep M, Adell, Albert, Planas, Anna M, Cristòfol, Rosa, Sanfeliu, Coral

“…Alzheimer's disease (AD) is a devastating age-related neurodegenerative disease. Age is the main risk factor for sporadic AD, which is the most prevalent type…”
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VAP-1/SSAO plasma activity and brain expression in human hemorrhagic stroke by Hernandez-Guillamon, Mar, Solé, Montse, Delgado, Pilar, García-Bonilla, Lidia, Giralt, Dolors, Boada, Cristina, Penalba, Anna, García, Sandra, Flores, Alan, Ribó, Marc, Alvarez-Sabin, José, Ortega-Aznar, Arantxa, Unzeta, Mercedes, Montaner, Joan

“…Vascular adhesion protein-1 (VAP-1) is a cell surface and circulating enzyme that belongs to the semicarbazide-sensitive amine oxidase (SSAO) family, which…”
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Proteomic study of neuron and astrocyte cultures from senescence-accelerated mouse SAMP8 reveals degenerative changes by Díez-Vives, Cristina, Gay, Marina, García-Matas, Silvia, Comellas, Francesc, Carrascal, Montserrat, Abian, Joaquín, Ortega-Aznar, Arantxa, Cristòfol, Rosa, Sanfeliu, Coral

“…Senescence-accelerated prone (SAMP) strain 8 mice suffer an earlier development of cognitive age-related pathologies and a shorter life span than conventional…”
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Expression of metallothionein-I, -II, and -III in Alzheimer disease and animal models of neuroinflammation by Hidalgo, Juan, Penkowa, Milena, Espejo, Carmen, Martínez-Cáceres, Eva M, Carrasco, Javier, Quintana, Albert, Molinero, Amalia, Florit, Sergi, Giralt, Mercedes, Ortega-Aznar, Arantxa

“…In recent years it has become increasingly clear that the metallothionein (MT) family of proteins is important in neurobiology. MT-I and MT-II are normally…”
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Brainstem Dysgenesis in an Infant Prenatally Exposed to Cocaine by Boix, Hector, MD, Ortega-Aznar, Arantxa, MD, Vazquez, Elida, MD, Salcedo, Salvador, MD, Roig-Quilis, Manuel, MD, PhD

“…Many authors described the effects on the fetus of maternal cocaine abuse during pregnancy. Vasoconstriction appears to be the common mechanism of action…”
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Expression of Bone Morphogenetic Proteins in Multiple Sclerosis Lesions by Costa, Carme, Eixarch, Herena, Martínez-Sáez, Elena, Calvo-Barreiro, Laura, Calucho, Maite, Castro, Zoraida, Ortega-Aznar, Arantxa, Ramón y Cajal, Santiago, Montalban, Xavier, Espejo, Carmen

“…Bone morphogenetic proteins (BMPs) are secreted proteins that belong to the transforming growth factor-β superfamily. In the adult brain, they modulate…”
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Tumores del sistema nervioso central en la infancia: aspectos clinicopatológicos by Ortega Aznar, Arantxa, Romero Vidal, Francisco Javier

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Plasma VAP-1/SSAO Activity Predicts Intracranial Hemorrhages and Adverse Neurological Outcome After Tissue Plasminogen Activator Treatment in Stroke by HERNANDEZ-GUILLAMON, Mar, GARCIA-BONILLA, Lidia, QUINTANA, Manolo, MOLINA, Carlos A, ALVAREZ-SABIN, José, ROSELL, Anna, UNZETA, Mercedes, MONTANER, Joan, SOLE, Montse, SOSTI, Victoria, PARES, Mireia, CAMPOS, Mireia, ORTEGA-AZNAR, Arantxa, DOMINGUEZ, Carmen, RUBIERA, Marta, RIBO, Marc

“…Vascular adhesion protein-1 (VAP-1) is a cell surface and circulating enzyme involved in recruitment of lymphocytes and neutrophils through its…”
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The Proteome of Human Brain After Ischemic Stroke by Cuadrado, Eloy, Rosell, Anna, Colomé, Nuria, Hernández-Guillamon, Mar, García-Berrocoso, Teresa, Ribo, Marc, Alcazar, Alberto, Ortega-Aznar, Arantxa, Salinas, Matilde, Canals, Francesc, Montaner, Joan

“…Although stroke is among the most common causes of death and chronic disability worldwide, the proteome of the ischemic human brain remains unknown. Only a few…”
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Stroke and Multi-Infarct Dementia as Presenting Symptoms of Giant Cell Arteritis: Report of 7 Cases and Review of the Literature by Solans-Laqué, Roser, Bosch-Gil, Josep Angel, Molina-Catenario, Carlos A., Ortega-Aznar, Arantxa, Alvarez-Sabin, José, Vilardell-Tarres, Miguel

“…Cerebrovascular accidents (CVAs) and multi-infarct dementia have rarely been reported as presenting symptoms of giant cell arteritis (GCA), although 3%-4% of…”
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Fas System Activation in Perihematomal Areas After Spontaneous Intracerebral Hemorrhage by DELGADO, Pilar, CUADRADO, Eloy, ROSELL, Anna, ALVAREZ-SABIN, José, ORTEGA-AZNAR, Arantxa, HERNANDEZ-GUILLAMON, Mar, PENALBA, Anna, MOLINA, Carlos A, MONTANER, Joan

“…Apoptosis has been implicated as the prominent form of cell death in the brain perihematomal region in animal models and in autopsy or postsurgical human…”
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