Search Results - "Azma, Toshiharu"

A possible role of decreased human serum albumin in the endothelial dysfunction caused by albuminuria by Kinoshita, Hiroyuki, Azma, Toshiharu

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Cytoskeleton-disrupting agent cytochalasin B reduces oxidative stress caused by high glucose in the human arterial smooth muscle by Takaishi, Kazumi, Kinoshita, Hiroyuki, Feng, Guo-Gang, Azma, Toshiharu, Kawahito, Shinji, Kitahata, Hiroshi

“…The role of cytoskeleton dynamics in the oxidative stress toward human vasculature has been unclear. The current study examined whether the…”
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The supine-to-prone position change induces modification of endotracheal tube cuff pressure accompanied by tube displacement by Minonishi, Toshiyuki, MD, PhD, Kinoshita, Hiroyuki, MD, PhD, Hirayama, Michiko, MD, Kawahito, Shinji, MD, PhD, Azma, Toshiharu, MD, PhD, Hatakeyama, Noboru, MD, PhD, Fujiwara, Yoshihiro, MD, PhD

“…Abstract Study Objectives To determine whether the supine-to-prone position change displaced the endotracheal tube (ETT) and, if so, whether the displacement…”
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Human serum albumin and oxidative stress in preeclamptic women and the mechanism of albumin for stress reduction by Kinoshita, Hiroyuki, Watanabe, Kazushi, Azma, Toshiharu, Feng, Guo-Gang, Akahori, Takahiko, Hayashi, Hisaki, Sato, Motohiko, Fujiwara, Yoshihiro, Wakatsuki, Akihiko

“…The present study to address one of the mechanisms in preeclampsia, examined whether levels of oxidative stress, human serum albumin, and endothelial function…”
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Mechanisms of action of anesthetics for the modulation of perioperative thrombosis: evidence for immune mechanisms from basic and clinical studies by Azma, Toshiharu, Tuluc, Florin, Ito, Taishin, Aoyama-Mani, Chikako, Kawahito, Shinji, Kinoshita, Hiroyuki

“…Thrombotic events occurring in either arteries or veins are the primary causes of fatal perioperative cardiovascular events. Risk factors for deep vein…”
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Protective effects of anesthetics on vascular function related to K⁺ channels by Kawahito, Shinji, Nakahata, Katsutoshi, Azma, Toshiharu, Kuroda, Yasuhiro, Cook, David J, Kinoshita, Hiroyuki

“…K(+) channels play an essential role in the membrane potential of arterial smooth muscle, and also in regulating contractile tone. Especially, in vascular…”
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Beneficial Effect of Propofol on Arterial Adenosine Triphosphate-sensitive K+ Channel Function Impaired by Thromboxane by HABA, Masanori, KINOSHITA, Hiroyuki, MATSUDA, Naoyuki, AZMA, Toshiharu, HAMA-TOMIOKA, Keiko, HATAKEYAMA, Noboru, YAMAZAKI, Mitsuaki, HATANO, Yoshio

“…It is not known whether thromboxane A2 impairs adenosine triphosphate (ATP)-sensitive K channel function via increased production of superoxide in blood…”
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The modulation of vascular ATP-sensitive K+ channel function via the phosphatidylinositol 3-kinase-Akt pathway activated by phenylephrine by Haba, Masanori, Hatakeyama, Noboru, Kinoshita, Hiroyuki, Teramae, Hiroki, Azma, Toshiharu, Hatano, Yoshio, Matsuda, Naoyuki

“…The present study examined the modulator role of the phosphatidylinositol 3-kinase (PI3K)-Akt pathway activated by the alpha-1 adrenoceptor agonist…”
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Roles of Phosphatidylinositol 3-Kinase-Akt and NADPH Oxidase in Adenosine 5' -Triphosphate-Sensitive K+ Channel Function Impaired by High Glucose in the Human Artery by KINOSHITA, Hiroyuki, MATSUDA, Naoyuki, KABA, Hikari, HATAKEYAMA, Noboru, AZMA, Toshiharu, NAKAHATA, Katsutoshi, KURODA, Yasuhiro, TANGE, Kazuaki, IRANAMI, Hiroshi, HATANO, Yoshio

“…The present study was designed to examine roles of the phosphatidylinositol 3-kinase-Akt pathway and reduced nicotinamide-adenine dinucleotide phosphate…”
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Propofol-induced relaxation of rat aorta is altered by aging by Sakai, Yoko, Kawahito, Shinji, Takaishi, Kazumi, Mita, Naoji, Kinoshita, Hiroyuki, Hatakeyama, Noboru, Azma, Toshiharu, Nakaya, Yutaka, Kitahata, Hiroshi

“…Background: Propofol causes vasodilation via endothelium-dependent and -independent mechanisms. Because endothelial function is impaired with aging, the…”
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交感神経ベータ受容体遮断薬：周術期使用を巡る学術的根拠の変遷 by 東, 俊晴

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Molecular Mechanisms of the Inhibitory Effects of Clonidine on Vascular Adenosine Triphosphate–Sensitive Potassium Channels by Kawahito, Shinji, Kawano, Takashi, Kitahata, Hiroshi, Oto, Jun, Takahashi, Akira, Takaishi, Kazumi, Harada, Nagakatsu, Nakagawa, Tadahiko, Kinoshita, Hiroyuki, Azma, Toshiharu, Nakaya, Yutaka, Oshita, Shuzo

“…We investigated the effects of the imidazoline-derived α2-adrenoceptor agonist clonidine on vascular adenosine triphosphate-sensitive potassium (K(ATP))…”
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The Role of 20-Hydroxyeicosatetraenoic Acid in Cerebral Arteriolar Constriction and the Inhibitory Effect of Propofol by Hama-Tomioka, Keiko, Kinoshita, Hiroyuki, Azma, Toshiharu, Nakahata, Katsutoshi, Matsuda, Naoyuki, Hatakeyama, Noboru, Kikuchi, Hirosato, Hatano, Yoshio

“…We conducted this study to examine, in cerebral parenchymal arterioles, whether 20-hydroxyeicosatetraenoic acid (20-HETE) induces constrictor responses via…”
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Propofol Restores Brain Microvascular Function Impaired by High Glucose via the Decrease in Oxidative Stress by NAKAHATA, Katsutoshi, KINOSHITA, Hiroyuki, AZMA, Toshiharu, MATSUDA, Naoyuki, HAMA-TOMIOKA, Keiko, HABA, Masanori, HATANO, Yoshio

“…Vascular dysfunction induced by hyperglycemia has not been studied in cerebral parenchymal circulation. The current study was designed to examine whether high…”
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Beta Adrenergic Receptor Antagonists：A Paradigm Shift in Practical Guidelines for the Management of Patients Undergoing Noncardiac Surgery by AZMA, Toshiharu

“…Among the major antihypertensive drug classes, beta adrenergic receptor antagonists（beta blockers）have beneficial effects in protecting cardiac function…”
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Isoflurane Pretreatment Preserves Adenosine Triphosphate–Sensitive K+ Channel Function in the Human Artery Exposed to Oxidative Stress Caused by High Glucose Levels by Kinoshita, Hiroyuki, Matsuda, Naoyuki, Iranami, Hiroshi, Ogawa, Koji, Hatakeyama, Noboru, Azma, Toshiharu, Kawahito, Shinji, Yamazaki, Mitsuaki

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Inhibitory Effect of High Concentration of Glucose on Relaxations to Activation of ATP-Sensitive K+ Channels in Human Omental Artery by Kinoshita, Hiroyuki, Azma, Toshiharu, Nakahata, Katsutoshi, Iranami, Hiroshi, Kimoto, Yoshiki, Dojo, Mayuko, Yuge, Osafumi, Hatano, Yoshio

“…OBJECTIVE—The present study was designed to examine in the human omental artery whether high concentrations of D-glucose inhibit the activity of ATP-sensitive…”
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Prothrombotic roles of substance-P, neurokinin-1 receptors and leukocytes in the platelet-dependent clot formation in whole blood by Azma, Toshiharu, Matsubara, Yuki, Kinoshita, Hiroyuki, Hidaka, Ikuhiro, Shiraishi, Seiji, Nakao, Masakazu, Kawamoto, Masashi, Yuge, Osafumi, Hatano, Yoshio

“…A number of types of non-neuronal cells including leukocytes have been confirmed to possess substance-P and its specific neurokinin-1 receptor (NK1R), while…”
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New frontier in perioperative blood component therapy--preface and comments by Azma, Toshiharu, Kikuchi, Hirosato

“…The latest revision of Japanese practical guidelines for the blood component therapy, edited by the Ministry of Health, Labour and Welfare of Japan in 2005,…”
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Diagnosis and transfusion algorithm for the management of perioperative coagulopathy by Azma, Toshiharu, Yamasaki, Kyoko, Mimasu, Masashi, Nakao, Masakazu, Kikuchi, Hirosato

“…The present article reviewed the management of coagulopathy in the perioperative setting, following the Japanese practical guidelines for the blood component…”
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