Search Results - "Azizi, Paymon M"

Clathrin-dependent entry and vesicle-mediated exocytosis define insulin transcytosis across microvascular endothelial cells by Azizi, Paymon M, Zyla, Roman E, Guan, Sha, Wang, Changsen, Liu, Jun, Bolz, Steffen-Sebastian, Heit, Bryan, Klip, Amira, Lee, Warren L

“…Transport of insulin across the microvasculature is necessary to reach its target organs (e.g., adipose and muscle tissues) and is rate limiting in insulin…”
Get full text

Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis by Pillon, Nicolas J, Azizi, Paymon M, Li, Yujin E, Liu, Jun, Wang, Changsen, Chan, Kenny L, Hopperton, Kathryn E, Bazinet, Richard P, Heit, Bryan, Bilan, Philip J, Lee, Warren L, Klip, Amira

“…Obesity is associated with inflammation and immune cell recruitment to adipose tissue, muscle and intima of atherosclerotic blood vessels. Obesity and…”
Get more information

Troponin Testing After Noncardiac Surgery in Ontario: An Observational Study by Azizi, Paymon M., Wijeysundera, Duminda N., Wijeysundera, Harindra C., Austin, Peter C., Jerath, Angela, Han, Lu, Koh, Maria, Ko, Dennis T.

“…In 2017, the Canadian Cardiovascular Society (CCS) published guidelines recommending postoperative troponin surveillance in higher-risk patients having major…”
Get full text

Association Between Hospital Postoperative Troponin Use and Patient Outcomes After Vascular Surgery by Azizi, Paymon M., Wijeysundera, Duminda N., Wijeysundera, Harindra C., Austin, Peter C., Jerath, Angela, Kayssi, Ahmed, Ko, Dennis T.

“…Acute myocardial injury after noncardiac surgery, which is most often symptomatically silent, is associated with increased mortality and morbidity. However, it…”
Get full text

The cost-effectiveness of transcatheter aortic valve replacement in low surgical risk patients with severe aortic stenosis by Tam, Derrick Y, Azizi, Paymon M, Fremes, Stephen E, Chikwe, Joanna, Gaudino, Mario, Wijeysundera, Harindra C

“…Abstract Aims The economic value of transcatheter aortic valve replacement (TAVR) in low surgical risk patients with severe, symptomatic aortic stenosis is not…”
Get full text

Troponin testing after noncardiac surgery: a population-based historical cohort study on variation and factors associated with testing in Ontario by Azizi, Paymon M., Wijeysundera, Duminda N., Wijeysundera, Harindra C., Austin, Peter C., Jerath, Angela, Han, Lu, Koh, Maria, Ko, Dennis T.

“…Background International practice guidelines make different recommendations for postoperative troponin testing to detect perioperative myocardial infarction…”
Get full text

Renin‐angiotensin‐aldosterone system inhibitors and major cardiovascular events and acute kidney injury in patients with coronary artery disease by Sud, Maneesh, Ko, Dennis T., Chong, Alice, Koh, Maria, Azizi, Paymon M., Austin, Peter C., Stukel, Thérèse A., Jackevicius, Cynthia A.

“…Background Renin‐angiotensin‐aldosterone system inhibitors (RAASIs) are recommended for most patients with coronary artery disease (CAD). However, there is…”
Get full text

Prostaglandin I2 Receptor Agonism Preserves [Beta]-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms by Batchu, Sri N, Majumder, Syamantak, Bowskill, Bridgit B, White, Kathryn E, Advani, Suzanne L, Brijmohan, Angela S, Liu, Youan, Thai, Kerri, Azizi, Paymon M, Lee, Warren L, Advani, Andrew

“…Diabetic kidney disease (DKD) remains the leading cause of end-stage renal disease (ESRD) in the developed world. In the U.S., the prevalence of both diabetes…”
Get full text

Prostaglandin I2 Receptor Agonism Preserves β-Cell Function and Attenuates Albuminuria Through Nephrin-Dependent Mechanisms by Batchu, Sri N, Majumder, Syamantak, Bowskill, Bridgit B, White, Kathryn E, Advani, Suzanne L, Brijmohan, Angela S, Liu, Youan, Thai, Kerri, Azizi, Paymon M, Lee, Warren L, Advani, Andrew

“…Discovery of common pathways that mediate both pancreatic β-cell function and end-organ function offers the opportunity to develop therapies that modulate…”
Get full text

Left ventricular strain analysis using cardiac magnetic resonance imaging in patients undergoing in‐centre nocturnal haemodialysis by Ong, Jann P, Wald, Ron, Goldstein, Marc B, Leipsic, Jonathon, Kiaii, Mercedeh, Deva, Djeven P, Kirpalani, Anish, Jimenez‐Juan, Laura, Bello, Olugbenga, Azizi, Paymon M, Wald, Rachel M, Wright, Graham A, Harel, Ziv, Connelly, Kim A, Yan, Andrew T

“…ABSTRACT Aim Intensified haemodialysis is associated with regression of left ventricular (LV) mass. Compared to LV ejection fraction, LV strain allows more…”
Get full text

Abstract 14288: Substantial Hospital-level Variation in Troponin Testing After Non-cardiac Surgery by Azizi, Paymon M, Han, Lu, Koh, Maria, Jerath, Angela, Wijeysundera, Harindra C, Wijeysundera, Duminda N, Austin, Peter, Ko, Dennis T

“…IntroductionThere is an increasing emphasis in detecting postoperative myocardial infarction (PMI) using routine troponin testing after non-cardiac surgery…”
Get full text

Abstract 8909: High Hospital-Specific Postoperative Troponin Testing Intensity Was Associated With Improved Outcomes After Major Vascular Surgery by Azizi, Paymon M, Wijeysundera, Duminda N, Wijeysundera, Harindra C, Austin, Peter, Jerath, Angela, Han, Lu, Koh, Maria, Kayssi, Ahmed, Ko, Dennis T

“…BackgroundAcute myocardial injury after non-cardiac surgery is associated with increased mortality and cardiovascular morbidity, but it is not known if…”
Get full text

Abstract 324: Use of Troponin Testing After Non-cardiac Surgery in Ontario by Azizi, Paymon M, Koh, Maria, Austin, Peter, Han, Lu, Jerath, Angela, Wijeysundera, Duminda N, Wijeysundera, Harindra C, Ko, Dennis T

“…Abstract only Background: Myocardial infarction after non-cardiac surgery is common and associated with worse patient outcomes. In 2017, the Canadian…”
Get full text