Search Results - "Aziz, A M"

Questions concerning the proximal origin of SARS‐CoV‐2 by Seyran, Murat, Pizzol, Damiano, Adadi, Parise, El‐Aziz, Tarek M. A., Hassan, Sk. Sarif, Soares, Antonio, Kandimalla, Ramesh, Lundstrom, Kenneth, Tambuwala, Murtaza, Aljabali, Alaa A. A., Lal, Amos, Azad, Gajendra K., Choudhury, Pabitra P., Uversky, Vladimir N., Sherchan, Samendra P., Uhal, Bruce D., Rezaei, Nima, Brufsky, Adam M.

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Outdoor activities foster local plant knowledge in Karelia, NE Europe by Mattalia, G., Svanberg, I., Ståhlberg, S., Kuznetsova, N., Prūse, B., Kolosova, V., Aziz, M. A., Kalle, R., Sõukand, R.

“…Wild edible plants, particularly berries, are relevant nutritional elements in the Nordic countries. In contrast to decreasing global trends, approximately 60%…”
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Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study by El-Sayed, Magda A.-A., Abdel-Aziz, Naglaa I., Abdel-Aziz, Alaa A.-M., El-Azab, Adel S., Asiri, Yousif A., ElTahir, Kamal E.H.

“…A series of hydrazone and pyrazole derivatives were prepared and evaluated for their anti-inflammatory activities and selectivity as COX-2 inhibitor. New…”
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Structural alterations based on naproxen scaffold: Synthesis, evaluation of antitumor activity and COX-2 inhibition, and molecular docking by El-Husseiny, Walaa M., El-Sayed, Magda A.-A., Abdel-Aziz, Naglaa I., El-Azab, Adel S., Asiri, Yousif A., Abdel-Aziz, Alaa A.-M.

“…A new series of non-carboxylic naproxen analogues, bearing a variety of ring systems, such as oxadiazoles 3a–c and 6a–c, cycloalkanes 4a–d, cyclic imides 5a–c,…”
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Synthesis, enzyme inhibition assay, and molecular modeling study of novel pyrazolines linked to 4-methylsulfonylphenyl scaffold: antitumor activity and cell cycle analysis by Abdel-Aziz, Alaa A.-M, El-Azab, Adel S, Brogi, Simone, Ayyad, Rezk R, Alkahtani, Hamad M, Abuelizz, Hatem A, Al-Suwaidan, Ibrahim A, Al-Obaid, Abdulrahman M

“…Antitumor activity using 59 cancer cell lines and enzyme inhibitory activity of a newly synthesized pyrazoline-linked 4-methylsulfonylphenyl scaffold…”
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Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities by Alanazi, Amer M., El-Azab, Adel S., Al-Suwaidan, Ibrahim A., ElTahir, Kamal Eldin H., Asiri, Yousif A., Abdel-Aziz, Naglaa I., Abdel-Aziz, Alaa A.-M.

“…A group of 30 cyclic imides (1–10a-c) was designed for evaluation as a selective COX-2 inhibitor and investigated in vivo for anti-inflammatory and analgesic…”
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Synthesis and In Vitro Anticancer Activity of Novel 4-Aryl-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridines Arrest Cell Cycle and Induce Cell Apoptosis by Inhibiting CDK2 and/or CDK9 by Almansour, Basma S., Binjubair, Faizah A., Abdel-Aziz, Alaa A.-M., Al-Rashood, Sara T.

“…Two series of pyrazolo[3,4-b]pyridine derivatives, 9a–h and 14a–h, are synthesized and evaluated for their anti-cancer potency towards Hela, MCF7, and HCT-116…”
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Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2 by El-Sayed, Magda A.-A., Abdel-Aziz, Naglaa I., Abdel-Aziz, Alaa A.-M., El-Azab, Adel S., ElTahir, Kamal E.H.

“…New pyrazole and pyrazoline derivatives have been synthesized and their ability to inhibit ovine COX-1/COX-2 isozymes was evaluated using in vitro…”
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Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: Molecular docking study by El-Azab, Adel S., Al-Omar, Mohamed A., Abdel-Aziz, Alaa A.-M., Abdel-Aziz, Naglaa I., El-Sayed, Magda A.-A., Aleisa, Abdulaziz M., Sayed-Ahmed, Mohamed M., Abdel-Hamide, Sami G.

“…Novel derivatives of quinazoline ( 1– 27) have been synthesized and tested for their antitumor activity against three tumor cell lines among these cell lines…”
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Exploration of thiazolidine‐2,4‐diones as tyrosine kinase inhibitors: Design, synthesis, ADMET, docking, and antiproliferative evaluations by Aziz, Nada A. A. M., George, Riham F., El‐Adl, Khaled, Mahmoud, Walaa R.

“…As dual EGFR and VEGFR‐2 inhibitors, 22 innovative thiazolidine‐2,4‐diones were modeled, constructed, and measured for their anticancer performance versus four…”
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Strength of Thixoformed A319 Alloy at Elevated Temperature by Aziz, A. M., Omar, M. Z., Sajuri, Z.

“…When alloys are exposed to elevated temperatures they experience a decrement in their mechanical properties that leads to material failure. However, the use of…”
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Adsorption of methyl orange from aqueous solution onto calcined Lapindo volcanic mud by Jalil, Aishah A., Triwahyono, Sugeng, Adam, S. Hazirah, Rahim, N. Diana, Aziz, M. Arif A., Hairom, N. Hanis H., Razali, N. Aini M., Abidin, Mahani A.Z., Mohamadiah, M. Khairul A.

“…In this study, calcined Lapindo volcanic mud (LVM) was used as an adsorbent to remove an anionic dye, methyl orange (MO), from an aqueous solution by the batch…”
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Methanation of carbon dioxide on metal-promoted mesostructured silica nanoparticles by Aziz, M.A.A., Jalil, A.A., Triwahyono, S., Sidik, S.M.

“…•The effect of metal on MSN was studied for methanation of CO2.•Areal rates followed the order Ni/MSN>Rh/MSN>Ru/MSN>Fe/MSN>Cu/MSN>Ir/MSN.•Metal dissociated CO2…”
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Synchronization in a Three Level Network of All-to-All Periodically Forced Hodgkin–Huxley Reaction–Diffusion Equations by Ambrosio, B., Aziz-Alaoui, M. A., Oujbara, A.

“…This article focuses on the analysis of dynamics emerging in a network of Hodgkin–Huxley reaction–diffusion equations. The network has three levels. The three…”
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Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide by El-Azab, Adel S, Abdel-Aziz, Alaa A-M, Ghabbour, Hazem A, Bua, Silvia, Nocentini, Alessio, Alkahtani, Hamad M, Alsaif, Nawaf A, Al-Agamy, Mohamed H M, Supuran, Claudiu T

“…Human carbonic anhydrase (CA, EC 4.2.1.1) (hCA) isoforms I, II, IX, and XII were investigated for their inhibitory activity with a series of new Schiff's bases…”
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Trends and Paradoxes of Competitive Evolution in the Predation Mechanism by Sanchez-Palencia, Evariste, Aziz-Alaoui, M. A.

“…We give a series of numerical examples of competitive evolution in the predation system, showing in some cases how the choice is made to increase the…”
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Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study by El-Sayed, Magda A.-A., El-Husseiny, Walaa M., Abdel-Aziz, Naglaa I., El-Azab, Adel S., Abuelizz, Hatem A., Abdel-Aziz, Alaa A.-M.

“…A new series of 4,6-disubstituted 2-(4-(dimethylamino)styryl)quinoline 4a,b-9a,b was synthesized by the reaction of 2-(4-(dimethylamino)styryl)-6-substituted…”
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Design, synthesis, and docking of novel thiazolidine‐2,4‐dione multitarget scaffold as new approach for cancer treatment by Hanafy, Noura S., Aziz, Nada A. A. M., El‐Hddad, Sanadelaslam S. A., Abdelgawad, Mohamed A., Ghoneim, Mohammed M., Dawood, Amal F., Mohamady, Samy, El‐Adl, Khaled, Ahmed, Sahar

“…Novel thiazolidine‐2,4‐diones have been developed and estimated as conjoint inhibitors of EGFRT790M and VEGFR‐2 against HCT‐116, MCF‐7, A549, and HepG2 cells…”
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Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationship of Substituted Quinazolinones as Cyclin-Dependent Kinase 9 Inhibitors by Alkahtani, Hamad M, Zen, Amer Alhaj, Obaidullah, Ahmad J, Alanazi, Mohammed M, Almehizia, Abdulrahman A, Ansari, Siddique Akber, Aleanizy, Fadilah Sfouq, Alqahtani, Fulwah Yahya, Aldossari, Rana M, Algamdi, Raghad Abdullah, Al-Rasheed, Lamees S, Abdel-Hamided, Sami G, Abdel-Aziz, Alaa A-M, El-Azab, Adel S

“…Cyclin-dependent kinase 9 (CDK9) plays a critical role in transcriptional elongation, through which short-lived antiapoptotic proteins are overexpressed and…”
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Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study by Abdel-Aziz, Alaa A.-M., ElTahir, Kamal E.H., Asiri, Yousif A.

“…A group of cyclic imides ( 1– 13) was designed for evaluation as selective COX-2 inhibitors and investigated in vivo for their anti-inflammatory activities…”
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