Search Results - "Azia, Ariel"

Searching DNA via a “Monkey Bar” Mechanism: The Significance of Disordered Tails by Vuzman, Dana, Azia, Ariel, Levy, Yaakov

“…The search through nonspecific DNA for a specific site by proteins is known to be facilitated by sliding, hopping, and intersegment transfer between separate…”
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Use of Host-like Peptide Motifs in Viral Proteins Is a Prevalent Strategy in Host-Virus Interactions by Hagai, Tzachi, Azia, Ariel, Babu, M. Madan, Andino, Raul

“…Viruses interact extensively with host proteins, but the mechanisms controlling these interactions are not well understood. We present a comprehensive analysis…”
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What distinguishes GroEL substrates from other Escherichia coli proteins? by Azia, Ariel, Unger, Ron, Horovitz, Amnon

“…Experimental studies and theoretical considerations have shown that only a small subset of Escherichia coli proteins fold in vivo with the help of the GroE…”
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Intrinsic Disorder in Ubiquitination Substrates by Hagai, Tzachi, Azia, Ariel, Tóth-Petróczy, Ágnes, Levy, Yaakov

“…The ubiquitin–proteasome system is responsible for the degradation of numerous proteins in eukaryotes. Degradation is an essential process in many cellular…”
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Modulation of Folding Kinetics of Repeat Proteins: Interplay between Intra- and Interdomain Interactions by Hagai, Tzachi, Azia, Ariel, Trizac, Emmanuel, Levy, Yaakov

“…Repeat proteins have unique elongated structures that, unlike globular proteins, are quite modular. Despite their simple one-dimensional structure, repeat…”
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Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich proteins revealed by high-throughput microscopy analysis by Nadler-Holly, Michal, Breker, Michal, Gruber, Ranit, Azia, Ariel, Gymrek, Melissa, Eisenstein, Miriam, Willison, Keith R, Schuldiner, Maya, Horovitz, Amnon

“…The eukaryotic chaperonin containing t-complex polypeptide 1 (CCT/TRiC) is an ATP-fueled machine that assists protein folding. It consists of two back-to-back…”
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Nonnative Electrostatic Interactions Can Modulate Protein Folding: Molecular Dynamics with a Grain of Salt by Azia, Ariel, Levy, Yaakov

“…In recent years, a growing number of protein folding studies have focused on the unfolded state, which is now recognized as playing a major role in the folding…”
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Genome-wide computational determination of the human metalloproteome by Azia, Ariel, Levy, Ronen, Unger, Ron, Edelman, Marvin, Sobolev, Vladimir

“…ABSTRACT Accurate prediction of protein function in humans is important for understanding biological processes at the molecular level in biomedicine and drug…”
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Extensive use of Host-Mimicking Motifs Supports Complex Regulation of Viral Proteins by Hagai, Tzachi, Andino, Raul, Babu, Madan M., Azia, Ariel

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What distinguishes GroEL substrates from other Escherichiacoli proteins? by Azia, Ariel, Unger, Ron, Horovitz, Amnon

“…Experimental studies and theoretical considerations have shown that only a small subset of Escherichiacoli proteins fold invivo with the help of the GroE…”
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The origins and evolution of ubiquitination sites by Hagai, Tzachi, Tóth-Petróczy, Ágnes, Azia, Ariel, Levy, Yaakov

“…Protein ubiquitination is central to the regulation of various pathways in eukaryotes. The process of ubiquitination and its cellular outcome were investigated…”
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The Effects of Mutations on Protein Function: A Comparative Study of Three Databases of Mutations in Humans by Azia, Ariel, Uversky, Vladimir N., Horovitz, Amnon, Unger, Ron

“…Single‐nucleotide mutations (SNPs) in protein‐coding regions of the human genome are a major factor in determining human variation in health and disease. Here,…”
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