Search Results - "Azevedo, Vasco"
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An integrative in-silico approach for therapeutic target identification in the human pathogen Corynebacterium diphtheriae
Published in PloS one (19-10-2017)“…Corynebacterium diphtheriae (Cd) is a Gram-positive human pathogen responsible for diphtheria infection and once regarded for high mortalities worldwide. The…”
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Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target
Published in Frontiers in immunology (02-03-2021)“…Schistosomiasis remains a serious health issue nowadays for an estimated one billion people in 79 countries around the world. Great efforts have been made to…”
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Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Shows a Protective Effect on DNBS and DSS-Induced Colitis Model in Mice through Inhibition of NF-κB Pathway
Published in Frontiers in microbiology (01-02-2017)“…and its supernatant showed protective effects in different chemically-induced colitis models in mice. Recently, we described 7 peptides found in the…”
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Anticancer and Antiviral Properties of Cardiac Glycosides: A Review to Explore the Mechanism of Actions
Published in Molecules (Basel, Switzerland) (07-08-2020)“…Cardiac glycosides (CGs) have a long history of treating cardiac diseases. However, recent reports have suggested that CGs also possess anticancer and…”
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Possible Benefits of Faecalibacterium prausnitzii for Obesity-Associated Gut Disorders
Published in Frontiers in pharmacology (02-12-2021)“…Metabolic disorders are an increasing concern in the industrialized world. Current research has shown a direct link between the composition of the gut…”
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Multi-omics-based identification of SARS-CoV-2 infection biology and candidate drugs against COVID-19
Published in Computers in biology and medicine (01-11-2020)“…SARS-CoV-2 has ushered a global pandemic with no effective drug being available at present. Although several FDA-approved drugs are currently under clinical…”
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Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms
Published in Viruses (18-04-2021)“…The COVID-19 pandemic has infected millions worldwide, leaving a global burden for long-term care of COVID-19 survivors. It is thus imperative to study…”
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Insight of Genus Corynebacterium : Ascertaining the Role of Pathogenic and Non-pathogenic Species
Published in Frontiers in microbiology (12-10-2017)“…This review gathers recent information about genomic and transcriptomic studies in the genus, exploring, for example, prediction of pathogenicity islands and…”
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Sympathetic nerve-adipocyte interactions in response to acute stress
Published in Journal of molecular medicine (Berlin, Germany) (01-02-2022)“…Psychological stress predisposes our body to several disorders. Understanding the cellular and molecular mechanisms involved in the physiological responses to…”
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Functional Characterization of Novel Faecalibacterium prausnitzii Strains Isolated from Healthy Volunteers: A Step Forward in the Use of F. prausnitzii as a Next-Generation Probiotic
Published in Frontiers in microbiology (30-06-2017)“…is a major member of the Firmicutes phylum and one of the most abundant bacteria in the healthy human microbiota. depletion has been reported in several…”
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Hitac: a hierarchical taxonomic classifier for fungal ITS sequences compatible with QIIME2
Published in BMC bioinformatics (02-07-2024)“…Fungi play a key role in several important ecological functions, ranging from organic matter decomposition to symbiotic associations with plants. Moreover,…”
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Analysis of the microarray gene expression for breast cancer progression after the application modified logistic regression
Published in Gene (05-02-2020)“…Methods based around statistics and linear algebra have been increasingly used in attempts to address emerging questions in microarray literature. Microarray…”
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Staphylococcus epidermidis role in the skin microenvironment
Published in Journal of cellular and molecular medicine (01-09-2019)“…Wound healing is a complex dynamic physiological process in response to cutaneous destructive stimuli that aims to restore the cutaneous’ barrier role…”
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Extracellular vesicles produced by human and animal Staphylococcus aureus strains share a highly conserved core proteome
Published in Scientific reports (21-05-2020)“…Staphylococcus aureus is an important opportunistic pathogen of humans and animals. It produces extracellular vesicles (EVs) that are involved in cellular…”
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Applications of Silver Nanoparticles in Dentistry: Advances and Technological Innovation
Published in International journal of molecular sciences (02-03-2021)“…Silver nanoparticles (AgNPs) have been successfully applied in several areas due to their significant antimicrobial activity against several microorganisms. In…”
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GENPPI: standalone software for creating protein interaction networks from genomes
Published in BMC bioinformatics (16-12-2021)“…Bacterial genomes are being deposited into online databases at an increasing rate. Genome annotation represents one of the first efforts to understand…”
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Two-Component Signal Transduction Systems of Pathogenic Bacteria As Targets for Antimicrobial Therapy: An Overview
Published in Frontiers in microbiology (10-10-2017)“…The bacterial communities in a wide range of environmental niches sense and respond to numerous external stimuli for their survival. Primarily, a source they…”
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Pathogenomics insights for understanding Pasteurella multocida adaptation
Published in International journal of medical microbiology (01-05-2020)“…•P. multocida can infect a wide range of hosts and cause different diseases.•P. multocida presents genomic flexibility in host adaptation and…”
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Sensory nerves in the spotlight of the stem cell niche
Published in Stem cells translational medicine (01-03-2021)“…Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the…”
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Glioma Pericytes Promote Angiogenesis by Producing Periostin
Published in Cellular and molecular neurobiology (01-04-2022)“…Glioma is the prevalent aggressive primary brain tumor, with a very poor prognosis. The absence of advanced understanding of the roles played by the cells…”
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