Search Results - "Azevedo, Patrick O"

Pericytes in the Premetastatic Niche by Paiva, Ana E, Lousado, Luiza, Guerra, Daniel A P, Azevedo, Patrick O, Sena, Isadora F G, Andreotti, Julia P, Santos, Gabryella S P, Gonçalves, Ricardo, Mintz, Akiva, Birbrair, Alexander

“…The premetastatic niche formed by primary tumor-derived molecules contributes to fixation of cancer metastasis. The design of efficient therapies is limited by…”
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Endothelial Cells as Precursors for Osteoblasts in the Metastatic Prostate Cancer Bone by Paiva, Ana E., Lousado, Luiza, Almeida, Viviani M., Andreotti, Julia P., Santos, Gabryella S.P., Azevedo, Patrick O., Sena, Isadora F.G., Prazeres, Pedro H.D.M., Borges, Isabella T., Azevedo, Vasco, Mintz, Akiva, Birbrair, Alexander

“…Prostate cancer cells metastasize to the bones, causing ectopic bone formation, which results in fractures and pain. The cellular mechanisms underlying new…”
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Glioblastoma‐activated pericytes support tumor growth via immunosuppression by Sena, Isadora F. G., Paiva, Ana E., Prazeres, Pedro H. D. M., Azevedo, Patrick O., Lousado, Luiza, Bhutia, Sujit K., Salmina, Alla B., Mintz, Akiva, Birbrair, Alexander

“…Glioblastoma multiforme is the most common and aggressive primary brain tumor, with an extremely poor prognosis. The lack of detailed knowledge about the…”
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Differential requirement of neutralizing antibodies and T cells on protective immunity to SARS-CoV-2 variants of concern by Azevedo, Patrick O., Hojo-Souza, Natália S., Faustino, Lídia P., Fumagalli, Marcílio J., Hirako, Isabella C., Oliveira, Emiliano R., Figueiredo, Maria M., Carvalho, Alex F., Doro, Daniel, Benevides, Luciana, Durigon, Edison, Fonseca, Flávio, Machado, Alexandre M., Fernandes, Ana P., Teixeira, Santuza R., Silva, João S., Gazzinelli, Ricardo T.

“…The current COVID-19 vaccines protect against severe disease, but are not effective in controlling replication of the Variants of Concern (VOCs). Here, we used…”
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Targeting glioblastoma-derived pericytes improves chemotherapeutic outcome by Guerra, Daniel A. P., Paiva, Ana E., Sena, Isadora F. G., Azevedo, Patrick O., Silva, Walison N., Mintz, Akiva, Birbrair, Alexander

“…Glioblastoma is the most common malignant brain cancer in adults, with poor prognosis. The blood–brain barrier limits the arrival of several promising…”
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Endothelial cells maintain neural stem cells quiescent in their niche by Azevedo, Patrick O., Lousado, Luiza, Paiva, Ana E., Andreotti, Julia P., Santos, Gabryella S.P., Sena, Isadora F.G., Prazeres, Pedro H.D.M., Filev, Renato, Mintz, Akiva, Birbrair, Alexander

“…[Display omitted] •Soluble amyloid precursor protein suppresses neural stem cells growth in vitro.•Absence of amyloid precursor protein leads to neural stem…”
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SpiN-Tec: A T cell-based recombinant vaccine that is safe, immunogenic, and shows high efficacy in experimental models challenged with SARS-CoV-2 variants of concern by Hojo-Souza, Natália S., de Castro, Júlia T., Rivelli, Graziella G., Azevedo, Patrick O., Oliveira, Emiliano R., Faustino, Lídia P., Salazar, Natália, Bagno, Flávia F., Carvalho, Alex F., Rattis, Bruna, Lourenço, Karine L., Gomes, Isabela P., Assis, Bruna R.D., Piccin, Mariela, Fonseca, Flávio G., Durigon, Edison, Silva, João S., de Souza, Renan P., Goulart, Gisele A.C., Santiago, Helton, Fernandes, Ana Paula S., Teixeira, Santuza R., Gazzinelli, Ricardo T.

“…The emergence of new SARS-CoV-2 variants of concern associated with waning immunity induced by natural infection or vaccines currently in use suggests that the…”
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Perivascular cell αv integrins as a target to treat skeletal muscle fibrosis by Prazeres, Pedro H.D.M., Turquetti, Anaelise O.M., Azevedo, Patrick O., Barreto, Rodrigo S.N., Miglino, Maria A., Mintz, Akiva, Delbono, Osvaldo, Birbrair, Alexander

“…Fibrosis following injury leads to aberrant regeneration and incomplete functional recovery of skeletal muscle, but the lack of detailed knowledge about the…”
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Pericytes modulate myelination in the central nervous system by Azevedo, Patrick O., Sena, Isadora F.G., Andreotti, Julia P., Carvalho‐Tavares, Juliana, Alves‐Filho, José C., Cunha, Thiago M., Cunha, Fernando Q., Mintz, Akiva, Birbrair, Alexander

“…Multiple sclerosis is a highly prevalent chronic demyelinating disease of the central nervous system. Remyelination is the major therapeutic goal for this…”
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Cross-talk between lung cancer and bones results in neutrophils that promote tumor progression by Azevedo, Patrick O., Paiva, Ana E., Santos, Gabryella S. P., Lousado, Luiza, Andreotti, Julia P., Sena, Isadora F. G., Tagliati, Carlos A., Mintz, Akiva, Birbrair, Alexander

“…Lung cancer is the leading cause of cancer mortality around the world. The lack of detailed understanding of the cellular and molecular mechanisms…”
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Macrophages Generate Pericytes in the Developing Brain by Prazeres, Pedro H. D. M., Almeida, Viviani M., Lousado, Luiza, Andreotti, Julia P., Paiva, Ana E., Santos, Gabryella S. P., Azevedo, Patrick O., Souto, Luanny, Almeida, Gregório G., Filev, Renato, Mintz, Akiva, Gonçalves, Ricardo, Birbrair, Alexander

“…Pericytes are defined by their anatomical location encircling blood vessels' walls with their long projections. The exact embryonic sources of cerebral…”
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Adipocytes role in the bone marrow niche by Guerra, Daniel A. P., Paiva, Ana E., Sena, Isadora F. G., Azevedo, Patrick O., Batista, Miguel Luiz, Mintz, Akiva, Birbrair, Alexander

“…Adipocyte infiltration in the bone marrow follows chemotherapy or irradiation. Previous studies indicate that bone marrow fat cells inhibit hematopoietic stem…”
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Schwann cell precursors as a source for adrenal gland chromaffin cells by Lousado, Luiza, Prazeres, Pedro H D M, Andreotti, Julia P, Paiva, Ana E, Azevedo, Patrick O, Santos, Gabryella S P, Filev, Renato, Mintz, Akiva, Birbrair, Alexander

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LepR+ cells dispute hegemony with Gli1+ cells in bone marrow fibrosis by Sena, Isadora F. G., Borges, Isabella T., Lousado, Luiza, Azevedo, Patrick O., Andreotti, Julia P., Almeida, Viviani M., Paiva, Ana E., Santos, Gabryella S. P., Guerra, Daniel A. P., Prazeres, Pedro H. D. M., Souto, Luanny, Mintz, Akiva, Birbrair, Alexander

“…Bone marrow fibrosis is a reactive process, and a central pathological feature of primary myelofibrosis. Revealing the origin of fibroblastic cells in the bone…”
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Identity of Gli1+ cells in the bone marrow by Sena, Isadora F.G., Prazeres, Pedro H.D.M., Santos, Gabryella S.P., Borges, Isabella T., Azevedo, Patrick O., Andreotti, Julia P., Almeida, Viviani M., Paiva, Ana E., Guerra, Daniel A.P., Lousado, Luiza, Souto, Luanny, Mintz, Akiva, Birbrair, Alexander

“…•Bone marrow Gli1+ cells are heterogeneous at their location within the bone marrow.•Gli1+ cells provide a central cellular target in bone marrow…”
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Cover Image, Volume 233, Number 8, August 2018 by Azevedo, Patrick O., Sena, Isadora F.G., Andreotti, Julia P., Carvalho‐Tavares, Juliana, Alves‐Filho, José C., Cunha, Thiago M., Cunha, Fernando Q., Mintz, Akiva, Birbrair, Alexander

“…Cover: The cover image, by Azevedo et al., is based on the Perspective, Pericytes modulate myelination in the central nervous system, DOI: 10.1002/jcp.26348…”
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Pericytes in the pre-metastatic niche by Paiva, Ana E., Lousado, Luiza, Guerra, Daniel A. P., Azevedo, Patrick O., Sena, Isadora F. G., Andreotti, Julia P., Santos, Gabryella S. P., Gonçalves, Ricardo, Mintz, Akiva, Birbrair, Alexander

“…The pre-metastatic niche formed by primary tumor-derived molecules contributes to fixation of cancer metastasis. The design of efficient therapies is limited…”
Get full text