Search Results - "Azen, E. A"

PRB1, PRB2, and PRB4 coded polymorphisms among human salivary concanavalin-A binding, II-1, and Po proline- rich proteins by AZEN, E. A, AMBERGER, E, FISHER, S, PRAKOBPHOL, A, NIECE, R. L

“…Six closely linked PRP (proline-rich protein) genes code for many salivary PRPs that show frequent length and null variants. From determined protein sequences…”
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Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system by Maeda, N, Kim, H S, Azen, E A, Smithies, O

“…The nucleotide sequences of cDNAs coding for human salivary proline-rich proteins (PRPs) were determined. Clones cP1 and cP2 contain repetitive regions in…”
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Histatins, a family of salivary histidine-rich proteins, are encoded by at least two loci (HIS1 and HIS2) by Sabatini, L M, Azen, E A

“…We screened a human parotid gland cDNA library with mixed synthetic oligonucleotide probes representing a central coding region common to histatins 1 and 3…”
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Sucrose Octaacetate Avoidance in Nontaster Mice is not Enhanced by Two Type-A Prp Transgenes from Taster Mice by Harder, David B., Azen, Edwin A., Whitney, Glayde

“…The Soa bitter-sensitivity and Prp salivary-protein loci map to distal mouse chromosome six. No recombination has been found between sucrose octaacetate…”
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Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family by SABATINI, L. M, OTA, T, AZEN, E. A

“…Human histatins are a family of low-M(r), neutral to very basic, histidine-rich salivary polypeptides. They probably function as part of the nonimmune host…”
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Chromosome mapping of Soa, a gene influencing gustatory sensitivity to sucrose octaacetate in mice by CAPELESS, C. G, WHITNEY, G, AZEN, E. A

“…Strain distribution patterns among recombinant inbred strains suggested that a locus influencing taste sensitivity to sucrose octaacetate was on chromosome 6…”
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Many Protein Products From a Few Loci: Assignment of Human Salivary Proline-Rich Proteins to Specific Loci by Lyons, K. M, Azen, E. A, Goodman, P. A, Smithies, O

“…Earlier studies of protein polymorphisms led to the description of 13 linked loci thought to encode the human salivary proline-rich proteins (PRPs). However,…”
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Alleles at the PRB3 locus coding for a disulfide-bonded human salivary proline-rich glycoprotein (GI 8) and a null in an Ashkenazi Jew by AZEN, E. A, MINAGUCHI, K, LATREILLE, P, KIM, H.-S

“…From electrophoretic analysis, we identified in the saliva of an Ashkenazi Jew a disulfide-bonded major glycoprotein variant (Gl 8) that is a product of the…”
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Genetics of salivary protein polymorphisms by Azen, E A

“…Human salivary PRPs are determined by six closely linked genes on chromosome 12p13.2. The many PRPs show complex electrophoretic patterns that differ between…”
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Alleles at the PRH1 locus coding for the human salivary-acidic proline-rich proteins Pa, Db, and PIF by AZEN, E. A, HYUNG-SUK KIM, GOODMAN, P, FLYNN, S, MAEDA, N

“…We cloned and sequenced the entire exon and intron structures of Db and Pa genetic determinants at the PRH1 locus. Their derived amino acid sequences and that…”
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Proline-rich-protein promoters direct LacZ expression to the granular convoluted tubular cells of the submandibular gland in adult transgenic mice by ZHUO, L, MESSING, A, AZEN, E. A

“…The ability of two mouse PRP gene promoters to direct the expression of the bacterial lacZ reporter gene was tested in transgenic mice. Transgenes A1-lacZ and…”
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cDNA cloning and chromosomal localization (4q11-13) of a gene for statherin, a regulator of calcium in saliva by SABATINI, L. M, CARLOCK, L. R, JOHNSON, G. W, AZEN, E. A

“…On the basis of the known amino acid sequence of statherin, a human salivary protein, mixed synthetic oligonucleotides were synthesized and used to screen a…”
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Tissue distribution of RNAs for cystatins, histatins, statherin, and proline-rich salivary proteins in humans and macaques by Sabatini, L M, Warner, T F, Saitoh, E, Azen, E A

“…The tissue distribution of the mRNAs for a number of salivary proteins [proline-rich proteins (PRPs), statherin, cystatins, and the histatins] has been…”
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A frequent mutation in the acidic proline-rich protein gene, PRH2, causing a Q147K change closely adjacent to the bacterial binding domain of the cognate salivary PRP (Pr1') in Afro-Americans. Mutations in brief no. 154. Online by Azen, E A

“…The human salivary proline-rich proteins (PRPs) are coded by six closely linked genes on chromosome 12p13.2. Two of the PRP genes, PRH1 and PRH2, code for…”
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The human cystatin C gene (CST3) is a member of the cystatin gene family which is localized on chromosome 20 by Saitoh, E, Sabatini, L M, Eddy, R L, Shows, T B, Azen, E A, Isemura, S, Sanada, K

“…The fourth gene from the human cystatin gene family of salivary-type cysteine-proteinase inhibitors has been isolated and partially characterized by DNA…”
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Serial Cultivation of Epithelial Cells from Human and Macaque Salivary Glands by Sabatini, Linda M., Allen-Hoffmann, B. Lynn, Thomas F. Warner, Azen, Edwin A.

“…To study the regulation of human salivary-type gene expression we developed cell culture systems to support the growth and serial cultivation of salivary gland…”
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Human salivary proline-rich protein genes on chromosome 12 by AZEN, E. A, GOODMAN, P. A, LALLEY, P. A

“…A DNA probe (PRP1) for the proline-rich protein (PRP) genes was used to analyze the segregation of human PRP genes in human X mouse somatic cell hybrids…”
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Molecular genetics of human salivary proteins and their polymorphisms by Azen, E A, Maeda, N

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PRB2/1 fusion gene: a product of unequal and homologous crossing-over between proline-rich protein (PRP) genes PRB1 and PRB2 by Azen, E A, O'Connell, P, Kim, H S

“…The PRB2/1 fusion gene is produced by homologous and unequal crossing-over between PRB1 and PRB2 genes that code for basic salivary proline-rich proteins…”
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Structure and sequence determination of the gene encoding human salivary statherin by Sabatini, L M, He, Y Z, Azen, E A

“…Human statherin (STT) is a low-Mr (43 amino acids) acidic phosphoprotein secreted mainly by salivary glands. It acts as an inhibitor of precipitation of…”
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