Management of Ptosis in Kearns-Sayre Syndrome: A Case Report and Literature Review

Kearns-Sayre syndrome (KSS) is a rare mitochondrial disease that affects young adults, due to a deletion of mitochondrial DNA and characterized by the triad: age of onset lower than 20 years, chronic progressive external ophthalmoplegia, and an atypical pigmentary retinopathy. It is also characteriz...

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Bibliographic Details
Published in:	Archives of plastic surgery Vol. 51; no. 2; pp. 182 - 186
Main Authors:	Moustaine, Moulay O, Azemour, Zakaria, Mohammed, Frarchi, Benlanda, Othman, Nassik, Hicham, Karkouri, Mehdi
Format:	Journal Article
Language:	English
Published:	Korea (South) Thieme Medical Publishers, Inc 01-03-2024
Subjects:	chronic progressive external ophthalmoplegia Frontal suspension Kearns–Sayre syndrome Pediatric/Craniomilofacial/Head & Neck ptosis Kearns–Sayre syndrome Frontal suspension chronic progressive external ophthalmoplegia ptosis
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Summary:	Kearns-Sayre syndrome (KSS) is a rare mitochondrial disease that affects young adults, due to a deletion of mitochondrial DNA and characterized by the triad: age of onset lower than 20 years, chronic progressive external ophthalmoplegia, and an atypical pigmentary retinopathy. It is also characterized by other endocrine, neurological, and especially cardiac impairment with a very high risk of cardiac complications during surgical procedures under all types of anesthesia. We report a case of KSS revealed by severe bilateral ptosis and confirmed by a muscle biopsy with "ragged red fibers." The ptosis was surgically managed by cautious Frontal suspension under local anesthesia "Frontal nerve block." Through this case, we discuss challenges in the management of KSS patients.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2234-6163 2234-6171
DOI:	10.1055/a-2207-7587