Search Results - "Azechi, Kenji"

Cationic Gold(I)-Mediated Intramolecular Cyclization of 3-Alkyne-1,2-diols and 1-Amino-3-alkyn-2-ols: A Practical Route to Furans and Pyrroles by Egi, Masahiro, Azechi, Kenji, Akai, Shuji

“…The intramolecular cyclizations of the 3-alkyne-1,2-diols and the 1-amino-3-alkyn-2-ols with a low catalyst loading (0.05−0.5 mol %) of (Ph3P)AuCl−AgNTf2 or…”
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Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice by Yoshida, Tomoyuki, Yamagata, Atsushi, Imai, Ayako, Kim, Juhyon, Izumi, Hironori, Nakashima, Shogo, Shiroshima, Tomoko, Maeda, Asami, Iwasawa-Okamoto, Shiho, Azechi, Kenji, Osaka, Fumina, Saitoh, Takashi, Maenaka, Katsumi, Shimada, Takashi, Fukata, Yuko, Fukata, Masaki, Matsumoto, Jumpei, Nishijo, Hisao, Takao, Keizo, Tanaka, Shinji, Okabe, Shigeo, Tabuchi, Katsuhiko, Uemura, Takeshi, Mishina, Masayoshi, Mori, Hisashi, Fukai, Shuya

“…Neuroligin 3 (NLGN3) and neurexins (NRXNs) constitute a canonical transsynaptic cell-adhesion pair, which has been implicated in autism. In autism spectrum…”
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Identification of a Novel Protein Kinase A Inhibitor by Bioluminescence-Based Screening by Ishimoto, Tetsuya, Azechi, Kenji, Mori, Hisashi

“…We screened inhibitors in the adenylyl cyclase/protein kinase A/cAMP response element binding protein pathway (AC/PKA/CREB pathway) from a 2400 chemical…”
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Reusable and Durable Immobilized-Cationic Gold(I) Catalysts for Environmentally Benign Bond-Forming Reactions by Egi, Masahiro, Azechi, Kenji, Akai, Shuji

“…Polystyrene‐immobilized cationic gold catalysts 2a and 2b were synthesized for the first time and found to be highly effective catalysts for the bond‐forming…”
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Preparation and Regioselective Diels-Alder Reactions of Borylbenzynes: Synthesis of Functionalized Arylboronates by Ikawa, Takashi, Takagi, Akira, Kurita, Yurio, Saito, Kozumo, Azechi, Kenji, Egi, Masahiro, Kakiguchi, Keisuke, Kita, Yasuyuki, Akai, Shuji

“…B+[4+2]: 3‐Borylbenzynes undergo Diels–Alder reactions with substituted furans and pyrroles to give highly functionalized arylboronic acid derivatives with…”
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Efficacy of immune checkpoint inhibitor therapy in patients with pulmonary sarcomatoid carcinoma in clinical practice by Inomata, Minehiko, Tsuda, Takeshi, Ichikawa, Tomomi, Matsumoto, Masahiro, Mizushima, Isami, Azechi, Kenji, Takata, Naoki, Murayama, Nozomu, Hayashi, Kana, Hirai, Takahiro, Seto, Zenta, Tokui, Kotaro, Masaki, Yasuaki, Taka, Chihiro, Okazawa, Seisuke, Kambara, Kenta, Imanishi, Shingo, Taniguchi, Hirokazu, Miwa, Toshiro, Hayashi, Ryuji, Matsui, Shoko, Tobe, Kazuyuki

“…Objective Studies have suggested the potential efficacy of immune checkpoint inhibitors (ICIs) for pulmonary sarcomatoid carcinoma. This multicenter…”
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An observational study on the efficacy of targeted therapy for pulmonary sarcomatoid carcinoma by Tsuda, Takeshi, Ichikawa, Tomomi, Matsumoto, Masahiro, Mizusihima, Isami, Azechi, Kenji, Takata, Naoki, Murayama, Nozomu, Hayashi, Kana, Hirai, Takahiro, Seto, Zenta, Tokui, Kotaro, Masaki, Yasuaki, Taka, Chihiro, Okazawa, Seisuke, Kambara, Kenta, Imanishi, Shingo, Taniguchi, Hirokazu, Miwa, Toshiro, Hayashi, Ryuji, Matsui, Shoko, Inomata, Minehiko

“…Background Pulmonary sarcomatoid carcinoma is a rare tumor that is resistant to cytotoxic agents. This observational study aimed to evaluate the detection rate…”
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Association of Tumor PD-L1 Expression with the T790M Mutation and Progression-Free Survival in Patients with EGFR-Mutant Non-Small Cell Lung Cancer Receiving EGFR-TKI Therapy by Inomata, Minehiko, Azechi, Kenji, Takata, Naoki, Hayashi, Kana, Tokui, Kotaro, Taka, Chihiro, Okazawa, Seisuke, Kambara, Kenta, Imanishi, Shingo, Miwa, Toshiro, Hayashi, Ryuji, Matsui, Shoko, Tobe, Kazuyuki

“…Among patients with non-small cell lung cancer (NSCLC), we compared the progression-free survival (PFS) and proportion of acquisition of T790M mutation of the…”
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Cationic Gold(I)-Catalyzed Intramolecular Cyclization of γ-Hydroxyalkynones into 3(2H)-Furanones by Egi, Masahiro, Azechi, Kenji, Saneto, Moriaki, Shimizu, Kaori, Akai, Shuji

“…The combination of (p-CF3C6H4)3PAuCl and AgOTf generates a powerful catalyst for the intramolecular cyclizations of readily available γ-hydroxyalkynones under…”
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Preparation and Regioselective Diels-Alder Reactions of Borylbenzynes: Synthesis of Functionalized Arylboronates by Ikawa, Takashi, Takagi, Akira, Kurita, Yurio, Saito, Kozumo, Azechi, Kenji, Egi, Masahiro, Kakiguchi, Keisuke, Kita, Yasuyuki, Akai, Shuji

“…B+[4+2]: 3‐Borylbenzine reagieren in Diels‐Alder‐Reaktionen mit substituierten Furanen und Pyrrolen in guten bis perfekten Regioselektivitäten zu…”
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Efficient Intramolecular Cyclizations of Phenoxyethynyl Diols into Multisubstituted α,β-Unsaturated Lactones by Egi, Masahiro, Ota, Yuya, Nishimura, Yuka, Shimizu, Kaori, Azechi, Kenji, Akai, Shuji

“…AgOTf-catalyzed intramolecular cyclization of phenoxyethynyl diols proceeded under mild conditions to afford the multisubstituted α,β-unsaturated-γ-lactones in…”
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Generation of 3-borylbenzynes, their regioselective Diels–Alder reactions, and theoretical analysis by Takagi, Akira, Ikawa, Takashi, Kurita, Yurio, Saito, Kozumo, Azechi, Kenji, Egi, Masahiro, Itoh, Yuji, Tokiwa, Hiroaki, Kita, Yasuyuki, Akai, Shuji

“…3-Borylbenzynes were generated in situ from 6-boryl-2-iodophenyl trifluoromethanesulfonates using i-PrMgCl·LiCl and applied to Diels–Alder reactions with…”
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Case Series of Pleomorphic Carcinoma of the Lung Treated With Immune Checkpoint Inhibitors by Hayashi, Kana, Tokui, Kotaro, Inomata, Minehiko, Azechi, Kenji, Mizushima, Isami, Takata, Naoki, Taka, Chihiro, Okazawa, Seisuke, Kambara, Kenta, Imanishi, Shingo, Miwa, Toshiro, Hayashi, Ryuji, Matsui, Shoko, Nomura, Satoshi, Tobe, Kazuyuki

“…We report, herein, three cases of pleomorphic carcinoma of the lung treated with immune checkpoint inhibitors. Case 1: A 73-year-old man was diagnosed as…”
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Generation of 3-borylbenzynes, their regioselective DielsaAlder reactions, and theoretical analysis by Takagi, Akira, Ikawa, Takashi, Kurita, Yurio, Saito, Kozumo, Azechi, Kenji, Egi, Masahiro, Itoh, Yuji, Tokiwa, Hiroaki, Kita, Yasuyuki, Akai, Shuji

“…3-Borylbenzynes were generated in situ from 6-boryl-2-iodophenyl trifluoromethanesulfonates using i-PrMgClADTLiCl and applied to DielsaAlder reactions with…”
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Immune Checkpoint Inhibitor for Non-small Cell Lung Cancer With Negative or Low Tumor PD-L1 Expression by Inomata, Minehiko, Takata, Naoki, Mizushima, Isami, Azechi, Kenji, Hayashi, Kana, Tokui, Kotaro, Taka, Chihiro, Okazawa, Seisuke, Kambara, Kenta, Imanishi, Shingo, Miwa, Toshiro, Hayashi, Ryuji, Matsui, Shoko, Tobe, Kazuyuki

“…We conducted a retrospective analysis of the survival durations of 25 patients diagnosed as having non-squamous cell non-small cell lung cancer with negative…”
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Preparation and Regioselective Diels–Alder Reactions of Borylbenzynes: Synthesis of Functionalized Arylboronates by Ikawa, Takashi, Takagi, Akira, Kurita, Yurio, Saito, Kozumo, Azechi, Kenji, Egi, Masahiro, Kakiguchi, Keisuke, Kita, Yasuyuki, Akai, Shuji

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