Search Results - "Azarkan, Serap Yalcın"
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Investigation of the Therapeutic Effects of Palbociclib Conjugated Magnetic Nanoparticles on Different Types of Breast Cancer Cell Lines
Published in Cellular and molecular bioengineering (01-04-2023)“…Introduction Drug targeting and controlled drug release systems in cancer treatment have many advantages over conventional chemotherapy in terms of limiting…”
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First In Vitro–In Silico Analysis for the Determination of Antimicrobial and Antioxidant Properties of 2‑(4-Methoxyphenylamino)-2-oxoethyl Methacrylate and p‑Acetamide
Published in ACS omega (20-02-2024)“…The antibacterial, antifungal, and antioxidant activities of 2-chloro-N-(4-methoxyphenyl)acetamide (p-acetamide) and 2-(4-methoxyphenylamino)-2-oxoethyl…”
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In silico detection of Cucurbitacin-E on antioxidant enzymes of model organism Galleria mellonella L. (Lepidoptera: Pyralidae) and variation of antioxidant enzyme activities and lipid peroxidation in treated larvae
Published in Beni-Suef University journal of basic and applied sciences (01-12-2022)“…Background In silico studies further provided predictive binding properties of selected ligands for inhibition of target protein. In the study, molecular…”
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Determination of the relationship between doxorubicin resistance and Wnt signaling pathway in HeLa and K562 cell lines
Published in EXCLI journal (01-01-2018)“…Activation of the Wnt signaling in some types of cancer and its relation with chemotherapy resistance is a very interesting issue that has been emphasized in…”
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Evaluation of the effect of cannabidiol on the THLE-2 liver cell line exposed to lead
Published in The Science of the total environment (01-05-2024)“…Environmental and soil pollution increase the likelihood of human exposure to toxic metals. Therefore, there is a need for new methods and substances to…”
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New oxomethacrylate and acetamide: synthesis, characterization, and their computational approaches: molecular docking, molecular dynamics, and ADME analyses
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-11-2024)“…The compounds 2-chloro-N-(3-methoxyphenyl)acetamide (m-acetamide) and 2-(3-methoxyphenylamino)-2-oxoethyl methacrylate (3MPAEMA) were synthesized in this study…”
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Determination of the effect of L. plantarum AB6-25, L. plantarum MK55 and S. boulardii T8-3C microorganisms on colon, cervix, and breast cancer cell lines: Molecular docking, and molecular dynamics study
Published in Journal of molecular structure (05-08-2022)“…Cancer constitutes an important part of the diseases that are caused all over the world. Due to the side effects of commonly used treatment options such as…”
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The molecular interaction of human anti-apoptotic proteins and in silico ADMET, drug-likeness and toxicity computation of N-cyclohexylmethacrylamide
Published in Drug and chemical toxicology (New York, N.Y. 1978) (03-09-2022)“…Cancer is an uncontrolled growth of normal cells and apoptosis has an important role in cancer progression and cancer treatment. Antiapoptotic proteins are…”
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Synthesis, Characterization, Biological Evaluation and Molecular Docking Studies of New Oxoacrylate and Acetamide on HeLa Cancer Cell Lines
Published in Current computer-aided drug design (01-01-2021)“…In recent years, the discovery and development of new drugs play a critical role in cancer therapy. In this study, the effect of MPAEA and p-acetamide on…”
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The Determination of Molecular and Toxicological Mechanisms of Cucurbitacin E in Model Organism Drosophila melanogaster and Various Cancer Cell Lines: Molecular Modelling, Docking and Dynamic Simulation Studies
Published in Current computer-aided drug design (01-01-2023)“…Cucurbitacins are one of the most important components of Ecballium elaterium. Among the cucurbitacins, Cucurbitacin E was the first to be isolated. This study…”
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Antiproliferative effect of Lactobacillus plantarum l4 strain isolated from cervicovaginal microflora on hela cancer cell line
Published in İstanbul Tıp Fakültesi Dergisi (01-01-2022)“…Objective: Lactobacillus has been shown to inhibit proliferation of various cancer cells, but the effects of vaginal Lactobacillus on cervical cancer cells…”
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Sequence variants of CYP345a1 and CYP6a14 gene regions in Tribolium castaneum (Coleoptera: Tenebrionidae) adults treated with the novel characterızed Bolanthus turcicus (Caryophyllaceae) extract
Published in Molecular biology research communications (01-09-2020)“…In this study, various doses of plant extracts that obtained from was applied to an important storage pest adults. is an endemic species and spreads on the…”
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Determination of Antioxidant Activities of Viscum album L.: First Report on Interaction of Phenolics with Survivin Protein using in silico Analysis
Published in ChemistrySelect (Weinheim) (28-03-2023)“…Mistletoe, Viscum album L., (VA) known as “Ökse Otu” in Turkey, is a hemiparasitic shrub that grows especially on the trunks and crowns of broadleaf trees…”
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ANTIPROLIFERATIVE EFFECT OF LACTOBACILLUS PLANTARUM L4 STRAIN ISOLATED FROM CERVICOVAGINAL MICROFLORA ON HELA CANCER CELL LINE/SERVIKOVAJINAL MIKRO FLORADAN IZOLE EDILEN LACTOBACILLUS PLANTARUM L4 SUSUNUN HELA KANSER HUCRE HATTI UZERINDEKI ANTIPROLIFERATIF ETKISI
Published in İstanbul Tıp Fakültesi dergisi = Journal of the Istanbul Faculty of Medicine (01-03-2022)“…Objective: Lactobacillus has been shown to inhibit proliferation of various cancer cells, but the effects of vaginal Lactobacillus on cervical cancer cells…”
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Identification of Mitochondrial DNA Gene Mutations in a Turkish Head and Neck Squamous Cancer Patient Group
Published in Uluslararası hematologi-onkoloji dergisi (30-04-2022)Get full text
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Bazı probiyotik mikroorganizmaların farklı kanser hücre hatlarına sitotoksik etkisinin belirlenmesi: Determination of the cytotoxic effects of some probıotıc microorganisms on different cancer cell lines / Seda Yalçınkaya ; tez danışmanları, Prof. Dr. Aynur Gül Karahan Çakmakçı., Prof. Dr. Serap Yalçın Azarkan
Published 2022“…Bu çalışmada, potansiyel probiyotikler Lactiplantibacillus plantarum AB6-25, L. plantarum MK55 ve Saccharomyces boulardii T8-3C'nin HCT-116 kolon kanseri, HeLa…”
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Dissertation