Search Results - "Azarbarzin, Ali"
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Relationship between arousal intensity and heart rate response to arousal
Published in Sleep (New York, N.Y.) (01-04-2014)“…The visual appearance of cortical arousals varies considerably, from barely meeting scoring criteria to very intense arousals. Arousal from sleep is associated…”
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2
The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study
Published in European heart journal (07-04-2019)“…Abstract Aims Apnoea–hypopnoea index (AHI), the universal clinical metric of sleep apnoea severity, poorly predicts the adverse outcomes of sleep apnoea,…”
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3
The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity. A Randomized, Placebo-controlled, Double-Blind Crossover Trial
Published in American journal of respiratory and critical care medicine (15-05-2019)“…There is currently no effective pharmacological treatment for obstructive sleep apnea (OSA). Recent investigations indicate that drugs with noradrenergic and…”
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4
The Sleep Apnea-Specific Hypoxic Burden Predicts Incident Heart Failure
Published in Chest (01-08-2020)“…Heart failure (HF) is a leading cause of morbidity and mortality and although it is linked to sleep apnea, which physiological stressors most strongly…”
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Effects of the Combination of Atomoxetine and Oxybutynin on OSA Endotypic Traits
Published in Chest (01-06-2020)“…We recently showed that administration of the combination of the noradrenergic drug atomoxetine plus the antimuscarinic oxybutynin (ato-oxy) prior to sleep…”
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Sex differences in obstructive sleep apnea phenotypes, the multi-ethnic study of atherosclerosis
Published in Sleep (New York, N.Y.) (01-05-2020)“…Abstract Study Objectives The bases for sex disparities in obstructive sleep apnea (OSA), is poorly understood. We quantified the influences of event…”
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Arousal Intensity is a Distinct Pathophysiological Trait in Obstructive Sleep Apnea
Published in Sleep (New York, N.Y.) (01-12-2016)“…Abstract Study Objectives: Arousals from sleep vary in duration and intensity. Accordingly, the physiological consequences of different types of arousals may…”
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Quantifying the Arousal Threshold Using Polysomnography in Obstructive Sleep Apnea
Published in Sleep (New York, N.Y.) (01-01-2018)“…Abstract Study Objectives Precision medicine for obstructive sleep apnea (OSA) requires noninvasive estimates of each patient’s pathophysiological “traits.”…”
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Palatal prolapse as a signature of expiratory flow limitation and inspiratory palatal collapse in patients with obstructive sleep apnoea
Published in The European respiratory journal (01-02-2018)“…In some individuals with obstructive sleep apnoea (OSA), the palate prolapses into the velopharynx during expiration, limiting airflow through the nose or…”
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Predicting epiglottic collapse in patients with obstructive sleep apnoea
Published in The European respiratory journal (01-09-2017)“…Obstructive sleep apnoea (OSA) is characterised by pharyngeal obstruction occurring at different sites. Endoscopic studies reveal that epiglottic collapse…”
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Metabolomic profiles of sleep-disordered breathing are associated with hypertension and diabetes mellitus development
Published in Nature communications (28-02-2024)“…Sleep-disordered breathing (SDB) is a prevalent disorder characterized by recurrent episodic upper airway obstruction. Using data from the Hispanic Community…”
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12
Impact of reboxetine plus oxybutynin treatment for obstructive sleep apnea on cardiovascular autonomic modulation
Published in Scientific reports (23-02-2023)“…The combination of noradrenergic (reboxetine) plus antimuscarinic (oxybutynin) drugs (reb-oxy) reduced obstructive sleep apnea (OSA) severity but no data are…”
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Acetazolamide as an Add-on Therapy Following Barbed Reposition Pharyngoplasty in Obstructive Sleep Apnea: A Randomized Controlled Trial
Published in Life (Basel, Switzerland) (31-07-2024)“…Surgical interventions, like barbed reposition pharyngoplasty (BRP), are a valuable alternative for patients with obstructive sleep apnea (OSA) who are unable…”
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Effect of Dupilumab on Sleep Apnea Severity in Patients With Chronic Rhinosinusitis
Published in Sleep medicine research (01-06-2023)“…Patients with chronic rhinosinusitis (CRS) report improved sleep quality after dupilumab, an anti IL4/13 therapy. Concurrent CRS and obstructive sleep apnea…”
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Sleep Apnea-Specific Hypoxic Burden and Not the Sleepy Phenotype as a Novel Measure of Cardiovascular and Mortality Risk in a Clinical Cohort
Published in American journal of respiratory and critical care medicine (01-01-2022)“…Mehra and Azarbarzin discuss the paper by Trzepizur et al. which reports the associations of sleep apnea--specific hypoxic burden (HB) and risk of…”
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Snoring sounds variability as a signature of obstructive sleep apnea
Published in Medical engineering & physics (01-04-2013)“…Abstract Snoring sounds vary significantly within and between snorers. In this study, the variation of snoring sounds and its association with obstructive…”
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Obstructive sleep apnoea heterogeneity and cardiovascular disease
Published in Nature reviews cardiology (01-08-2023)“…Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway obstruction and intermittent hypoxaemia, is prevalent in patients with…”
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Physiologic Consequences of Upper Airway Obstruction in Sleep Apnea
Published in Chest (01-11-2024)“…OSA is diagnosed and managed by a metric called the apnea-hypopnea index (AHI). The AHI quantifies the number of respiratory events (apnea or hypopnea),…”
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Characteristics and reproducibility of novel sleep EEG biomarkers and their variation with sleep apnea and insomnia in a large community-based cohort
Published in Sleep (New York, N.Y.) (01-10-2021)“…Abstract Study Objectives New electroencephalogram (EEG) features became available for use in polysomnography and have shown promise in early studies. They…”
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IDENTIFICATION AND MONITORING OF MODERATE-TO-SEVERE OBSTRUCTIVE SLEEP APNEA USING RING-WORN PULSE OXIMETRY
Published in Chest (01-10-2024)Get full text
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