Search Results - "Azar, J."

Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation by Liu, David S., Duong, Cuong P., Haupt, Sue, Montgomery, Karen G., House, Colin M., Azar, Walid J., Pearson, Helen B., Fisher, Oliver M., Read, Matthew, Guerra, Glen R., Haupt, Ygal, Cullinane, Carleen, Wiman, Klas G., Abrahmsen, Lars, Phillips, Wayne A., Clemons, Nicholas J.

“…TP53 , a critical tumour suppressor gene, is mutated in over half of all cancers resulting in mutant-p53 protein accumulation and poor patient survival…”
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Selective Targeting of Cyclin E1-Amplified High-Grade Serous Ovarian Cancer by Cyclin-Dependent Kinase 2 and AKT Inhibition by Au-Yeung, George, Lang, Franziska, Azar, Walid J, Mitchell, Chris, Jarman, Kate E, Lackovic, Kurt, Aziz, Diar, Cullinane, Carleen, Pearson, Richard B, Mileshkin, Linda, Rischin, Danny, Karst, Alison M, Drapkin, Ronny, Etemadmoghadam, Dariush, Bowtell, David D L

“…Cyclin E1 ( ) amplification is associated with primary treatment resistance and poor outcome in high-grade serous ovarian cancer (HGSC). Here, we explore…”
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IGFBP-2 nuclear translocation is mediated by a functional NLS sequence and is essential for its pro-tumorigenic actions in cancer cells by Azar, W J, Zivkovic, S, Werther, G A, Russo, V C

“…IGFBP-2 is highly expressed in both the serum and tumor tissues of most cancers, and is considered one of the most significant genes in the signature of major…”
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Noncanonical IL6 Signaling-Mediated Activation of YAP Regulates Cell Migration and Invasion in Ovarian Clear Cell Cancer by Azar, Walid J, Christie, Elizabeth L, Mitchell, Chris, Liu, David S, Au-Yeung, George, Bowtell, David D L

“…Ovarian clear cell adenocarcinoma (OCCA) is characterized by a particularly poor response to conventional chemotherapy and a short overall survival time in…”
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Transcriptomic profiling of trophoblast fusion using BeWo and JEG-3 cell lines by Msheik, H, El Hayek, S, Bari, M Furqan, Azar, J, Abou-Kheir, W, Kobeissy, F, Vatish, M, Daoud, G

“…In human placenta, alteration in trophoblast differentiation has a major impact on placental maintenance and integrity. However, little is known about the…”
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EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas by Etemadmoghadam, Dariush, Azar, Walid J, Lei, Ying, Moujaber, Tania, Garsed, Dale W, Kennedy, Catherine J, Fereday, Sian, Mitchell, Chris, Chiew, Yoke-Eng, Hendley, Joy, Sharma, Raghwa, Harnett, Paul R, Li, Jason, Christie, Elizabeth L, Patch, Ann-Marie, George, Joshy, Au-Yeung, George, Mir Arnau, Gisela, Holloway, Timothy P, Semple, Timothy, Pearson, John V, Waddell, Nicola, Grimmond, Sean M, Köbel, Martin, Rizos, Helen, Lomakin, Ivan B, Bowtell, David D L, deFazio, Anna

“…Low-grade serous ovarian carcinomas (LGSC) are associated with a poor response to chemotherapy and are molecularly characterized by RAS pathway activation…”
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Racial/Ethnic Differences in Dyslipidemia Patterns by Frank, Ariel T.H, Zhao, Beinan, Jose, Powell O, Azar, Kristen M.J, Fortmann, Stephen P, Palaniappan, Latha P

“…BACKGROUND—No studies have comprehensively examined the prevalence of dyslipidemia, a major risk factor for cardiovascular disease, among diverse racial/ethnic…”
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The U.S. COVID-19 County Policy Database: a novel resource to support pandemic-related research by Hamad, Rita, Lyman, Kristin A, Lin, Feng, Modrow, Madelaine F, Ozluk, Pelin, Azar, Kristen M J, Goodin, Amie, Isasi, Carmen R, Kitzman, Heather E, Knight, Sara J, Marcus, Gregory M, McMahill-Walraven, Cheryl N, Meissner, Paul, Nair, Vinit, O'Brien, Emily C, Olgin, Jeffrey E, Peyser, Noah D, Sylwestrzak, Gosia, Williams, Natasha, Pletcher, Mark J, Carton, Thomas

“…It is increasingly recognized that policies have played a role in both alleviating and exacerbating the health and economic consequences of the COVID-19…”
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IGFBP-2 Enhances VEGF Gene Promoter Activity and Consequent Promotion of Angiogenesis by Neuroblastoma Cells by Azar, Walid J, Azar, Sheena H. X, Higgins, Sandra, Hu, Ji-Fan, Hoffman, Andrew R, Newgreen, Donald F, Werther, George A, Russo, Vincenzo C

“…IGF binding protein (IGFBP)-2 is one of the most significant genes in the signature of major aggressive cancers. Previously, we have shown that IGFBP-2…”
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Variability in engagement and progress in efficacious integrated collaborative care for primary care patients with obesity and depression: Within-treatment analysis in the RAINBOW trial by Lv, Nan, Xiao, Lan, Majd, Marzieh, Lavori, Philip W, Smyth, Joshua M, Rosas, Lisa G, Venditti, Elizabeth M, Snowden, Mark B, Lewis, Megan A, Ward, Elizabeth, Lesser, Lenard, Williams, Leanne M, Azar, Kristen M J, Ma, Jun

“…The RAINBOW randomized clinical trial validated the efficacy of an integrated collaborative care intervention for obesity and depression in primary care,…”
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Implementation of a group-based diabetes prevention program within a healthcare delivery system by Azar, Kristen M J, Nasrallah, Catherine, Szwerinski, Nina K, Petersen, John J, Halley, Meghan C, Greenwood, Deborah, Romanelli, Robert J

“…Group-based Diabetes Prevention Programs (DPP), aligned with recommendations from the Centers for Disease Control and Prevention, promote clinically…”
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Differing views regarding diet and physical activity: adolescents versus parents' perspectives by Azar, Kristen M J, Halley, Meghan, Lv, Nan, Wulfovich, Sharon, Gillespie, Katie, Liang, Lily, Goldman Rosas, Lisa

“…Today, approximately one in five United States adolescents age 12 to 19 years is obese and just over a third are either overweight or obese. This study…”
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A novel 6D-approach to radically transform undergraduate medical education: preliminary reflections from MBRU by Banerjee, Yajnavalka, Azar, Aida J, Tuffnell, Christopher, Lansberg, Peter J, Bayoumi, Riad, Davis, David

“…Designers of undergraduate medical education (UME) need to address the exponentially expanding volume and variability of scientific knowledge, where by…”
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Correction: Variability in engagement and progress in efficacious integrated collaborative care for primary care patients with obesity and depression: Within-treatment analysis in the RAINBOW trial by Lv, Nan, Xiao, Lan, Majd, Marzieh, Lavori, Philip W, Smyth, Joshua M, Rosas, Lisa G, Venditti, Elizabeth M, Snowden, Mark B, Lewis, Megan A, Ward, Elizabeth, Lesser, Lenard I, Williams, Leanne M, Azar, Kristen M. J, Ma, Jun

“…[This corrects the article DOI: 10.1371/journal.pone.0231743.]…”
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Flipped learning as an educational model in a cardiology residency program by Sierra-Fernández, Carlos R, Alejandra, Huipe-Dimas, Trevethan-Cravioto, Sergio A, Azar-Manzur, Francisco J, Mauricio, López-Meneses, Garnica-Geronimo, Luis R

“…Flipped learning (FL) is a model which allows students to adjust their study rhythm by taking advantage of class time to apply their knowledge. Although FL…”
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APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma by Liu, David S H, Read, Matthew, Cullinane, Carleen, Azar, Walid J, Fennell, Christina M, Montgomery, Karen G, Haupt, Sue, Haupt, Ygal, Wiman, Klas G, Duong, Cuong P, Clemons, Nicholas J, Phillips, Wayne A

“…p53 is a critical tumour suppressor and is mutated in 70% of oesophageal adenocarcinomas (OACs), resulting in chemoresistance and poor survival. APR-246 is a…”
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Design, Implementation, and Evaluation of a Distance Learning Framework to Adapt to the Changing Landscape of Anatomy Instruction in Medical Education During COVID-19 Pandemic: A Proof-of-Concept Study by Naidoo, Nerissa, Azar, Aida J., Khamis, Amar Hassan, Gholami, Mandana, Lindsbro, Marjam, Alsheikh-Ali, Alawi, Banerjee, Yajnavalka

“…This study presents the design of a DL-framework to deliver anatomy teaching that provides a microfiche of the onsite anatomy learning experience during the…”
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Study protocol for a pilot randomized, double-blind, placebo-controlled trial to investigate the anti-inflammatory effects of Frondanol in adults with inflammatory bowel disease by Ghelani, Hardik, Adrian, Thomas Edward, Ho, Samuel B., Akhras, Jamil, Azar, Aida J., Jan, Reem Kais

“…Inflammatory bowel disease (IBD), consisting of Crohn's disease and ulcerative colitis, is a debilitating condition with a rising incidence globally over…”
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IGFBP-2 - taking the lead in growth, metabolism and cancer by Yau, Steven W., Azar, Walid J., Sabin, Matthew A., Werther, George A., Russo, Vincenzo C.

“…The activity of the Insulin-like Growth Factors (IGFs) ligands elicited via their receptors and transduced by various intracellular signal pathways is…”
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Examining paradoxical session attendance and weight loss relationships in a clinic based lifestyle modification intervention by Azar, Kristen M. J., Sudat, Sylvia, Huang, Qiwen, Pressman, Alice P., Szwerinski, Nina K., Nasrallah, Catherine, Venditti, Elizabeth M., Romanelli, Robert J.

“…Objective Evaluations of lifestyle modification interventions (LMIs), modeled after the Diabetes Prevention Program, have repeatedly shown a dose‐response…”
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