Search Results - "Ayon, J."
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Robust empirical relationships for estimating the carbonate system in the southern California Current System and application to CalCOFI hydrographic cruise data (2005-2011)
Published in Journal of Geophysical Research: Oceans (01-05-2012)“…The California Current System (CCS) is expected to experience the ecological impacts of ocean acidification (OA) earlier than most other ocean regions because…”
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High-Throughput Screening of Natural Product and Synthetic Molecule Libraries for Antibacterial Drug Discovery
Published in Metabolites (02-05-2023)“…Due to the continued emergence of resistance and a lack of new and promising antibiotics, bacterial infection has become a major public threat. High-throughput…”
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Evidence for Upwelling of Corrosive "Acidified" Water onto the Continental Shelf
Published in Science (American Association for the Advancement of Science) (13-06-2008)“…The absorption of atmospheric carbon dioxide (CO₂) into the ocean lowers the pH of the waters. This so-called ocean acidification could have important…”
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LC-MS/MS-Based Separation and Quantification of Marfey’s Reagent Derivatized Proteinogenic Amino Acid dl-Stereoisomers
Published in Journal of the American Society for Mass Spectrometry (01-03-2019)“…d -Amino acids are important biological molecules. Improved analytical methods for their resolution and quantification remain of keen interest. In this study,…”
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PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension
Published in Proceedings of the National Academy of Sciences - PNAS (02-07-2019)“…Increased glycolysis in the lung vasculature has been connected to the development of pulmonary hypertension (PH). We therefore investigated whether glycolytic…”
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Features, roles and chiral analyses of proteinogenic amino acids
Published in AIMS molecular science (01-01-2020)“…Amino acids (AAs) are important biomolecules responsible for plethora of functions in both prokaryotic and eukaryotic systems. There are 22 naturally occurring…”
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Physical and biogeochemical controls of the carbonate system of the Yucatan Shelf
Published in Continental shelf research (15-07-2022)Get full text
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STIM2 (Stromal Interaction Molecule 2)–Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-03-2018)“…An increase in cytosolic free Ca concentration ([Ca]cyt) in pulmonary artery smooth muscle cells (PASMCs) triggers pulmonary vasoconstriction and stimulates…”
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Ocean acidification in the Gulf of Mexico: Drivers, impacts, and unknowns
Published in Progress in oceanography (01-12-2022)“…•We synthesize the current peer-reviewed literature on Gulf of Mexico (GOM) acidification across the ocean-estuarine continuum and identify critical knowledge,…”
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Correlative metabologenomics of 110 fungi reveals metabolite–gene cluster pairs
Published in Nature chemical biology (01-07-2023)“…Natural products research increasingly applies -omics technologies to guide molecular discovery. While the combined analysis of genomic and metabolomic…”
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Gaussian and linear deconvolution of LC-MS/MS chromatograms of the eight aminobutyric acid isomers
Published in Analytical biochemistry (01-01-2017)“…Isomeric molecules present a challenge for analytical resolution and quantification, even with MS-based detection. The eight aminobutyric acid (ABA) isomers…”
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Modulation of the vertical particle transfer efficiency in the oxygen minimum zone off Peru
Published in Biogeosciences (27-08-2018)“…The fate of the organic matter (OM) produced by marine life controls the major biogeochemical cycles of the Earth's system. The OM produced through…”
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Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension
Published in American journal of physiology. Lung cellular and molecular physiology (01-01-2019)“…The tumor-suppressive role of p53, a transcription factor that regulates the expression of many genes, has been linked to cell cycle arrest, apoptosis, and…”
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Extended vector fitting for subharmonics, harmonics, interharmonics, and supraharmonics estimation in electrical systems
Published in Electric power systems research (01-11-2023)“…The growth and integration of renewable energy and control systems in the utility grid represents a challenge for the electric power industry. Power quality…”
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Screening the NCI diversity set V for anti-MRSA activity: cefoxitin synergy and LC-MS/MS confirmation of folate/thymidine biosynthesis inhibition
Published in Microbiology spectrum (12-12-2023)“…New antibacterial agents are urgently needed to counter increasingly resistant bacteria. One approach to this problem is library screening for new…”
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MicroRNA-mediated downregulation of K + channels in pulmonary arterial hypertension
Published in American journal of physiology. Lung cellular and molecular physiology (01-01-2020)“…Downregulated expression of K channels and decreased K currents in pulmonary artery smooth muscle cells (PASMC) have been implicated in the development of…”
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Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension
Published in American journal of physiology. Lung cellular and molecular physiology (01-05-2016)“…An increase in cytosolic free Ca(2+) concentration ([Ca(2+)]cyt) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary…”
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Spider prey-wrapping silk is an α-helical coiled-coil/β-sheet hybrid nanofiber
Published in Chemical communications (Cambridge, England) (2018)“…Solid-State NMR results on 13C-Ala/Ser and 13C-Val enriched Argiope argentata prey-wrapping silk show that native, freshly spun aciniform silk nanofibers are…”
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Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
Published in JACC. Basic to translational science (01-12-2018)“…Visual Abstract…”
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