Search Results - "Ayodeji, Aturamu"
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Short chain fatty acid, acetate restores ovarian function in experimentally induced PCOS rat model
Published in PloS one (26-07-2022)“…Background Polycystic ovarian syndrome (PCOS) is pathogenically characterized with hyperandrogenism and metabolic alterations, which often result in ovarian…”
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2
Protective role of melatonin against adipose-hepatic metabolic comorbidities in experimentally induced obese rat model
Published in PloS one (08-12-2021)“…Adipose and hepatic metabolic dysfunctions are critical comorbidities that also aggravate insulin resistance in obese individuals. Melatonin is a low-cost…”
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3
Modulation of GABA by sodium butyrate ameliorates hypothalamic inflammation in experimental model of PCOS
Published in BMC neuroscience (23-11-2023)“…Polycystic ovarian syndrome (PCOS) is a known endocrine disorder that has affected many women of childbearing age, and is accompanied by various…”
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4
Heavy Metal Content of a Polyherbal Drug: Any Exposure-associated Public Health Risks?
Published in Journal of health sciences and surveillance system (01-04-2022)“…Background: Heavy metal contaminations of herbal formulations have constituted a public health challenge in the sub-Saharan Africa region and even in some…”
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5
Polyphenol-rich extract of Ocimum gratissimum leaves prevented toxic effects of cyclophosphamide on the kidney function of Wistar rats
Published in BMC complementary and alternative medicine (02-11-2021)“…Cyclophosphamide (CP) is one of the potent and low cost chemotherapy used in clinical setting against a variety of tumors. However, its association with…”
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6
Blockade of mineralocorticoid receptor by low-dose spironolactone rescues hypothalamic-ovarian dysfunction in PCOS experimental rat model
Published in Endocrine and metabolic science (01-12-2022)“…Studies have shown that women with polycystic ovarian syndrome (PCOS) undergo perturbations of the hypothalamic-pituitary ovarian axis, and frequently suffer…”
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7
Melatonin supplementation preserves testicular function by attenuating lactate production and oxidative stress in high fat diet-induced obese rat model
Published in Theriogenology (15-07-2022)“…Metabolic syndrome, including obesity has been documented as a critical factor in male reproductive dysfunction with subsequent reduction in male fertility…”
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8
Polyphenol-rich extract of Ocimum gratissimum leaves ameliorates colitis via attenuating colonic mucosa injury and regulating pro-inflammatory cytokines production and oxidative stress
Published in Biomedicine & pharmacotherapy (01-07-2018)“…[Display omitted] •Dextran sodium sulfate caused functional and structural impairments in the colonic tissues.•Ocimum gratissimum extract (PREOG) ameliorated…”
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9
Toxicological Evaluation of a Polyherbal Formulation on Testicular Function and Gonadal Histomorphology in Exposed Wistar Rats
Published in Biomedicine (Taipei) (01-01-2023)“…IntroductionDr Iguedo Goko Cleanser® is a herbal formulation (HF) widely marketed in southern Nigeria and purported to be very efficacious for the management…”
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10
Hepatic dysmetabolism in polycystic ovarian syndrome: impact of paraoxonase-1 modulation by butyrate
Published in Comparative clinical pathology (01-08-2024)“…The complications of endocrine-metabolic disorders among women of reproductive age, inclusively polycystic ovarian syndrome (PCOS), are cascade of events…”
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11
Barium chloride dose‐dependently induced heart and lung injury in Wistar rats
Published in Environmental toxicology (01-12-2019)“…Barium (Ba) is one of the environmental pollutant metals that incite deleterious effects on human health. The present study investigated the effects of…”
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12
Polycyclic aromatic hydrocarbons in a polyherbal drug: human health exposure-associated risk assessment study
Published in International journal of environmental health research (08-05-2024)“…PAHs are pervasive pollutants known to bioaccumulate in environmental matrices, plants, and humans. Dr. Iguedo Goko Cleanser® is a polyherbal drug with…”
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13
Mineralocorticoid receptor blockade attenuates hyperandrogenic metabolic dysregulation in letrozole-induced PCOS rat model
Published in Journal of diabetes and metabolic disorders (15-07-2022)“…Purpose Polycystic ovarian syndrome (PCOS) is a metabolic syndrome associated with mineralocorticoid receptor (MR) activation, which causes infertility in…”
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14
Panax ginseng supplementation protects against testicular damage induced by radiofrequency electromagnetic radiation from cell phone
Published in Nutrire : revista de Sociedade Brasileira de Alimentação e Nutrição = journal of the Brazilian Society of Food and Nutrition (18-09-2023)“…Purpose It is well-documented that radiofrequency electromagnetic radiation (RF-EMR) from the cell phone contributes to testicular dysfunction and subsequently…”
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15
Protective role of melatonin against adipose-hepatic metabolic comorbidities in experimentally induced obese rat model
Published in PloS one (01-01-2021)“…BackgroundAdipose and hepatic metabolic dysfunctions are critical comorbidities that also aggravate insulin resistance in obese individuals. Melatonin is a…”
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Journal Article -
16
Toxicity assessment of a polyherbal drug on haematological parameters, brain and spleen histoarchitecture in exposed Wistar rats
Published in Physiology and pharmacology (01-09-2023)Get full text
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