Search Results - "Aylott, J W"

Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds by Morris, G E, Bridge, J C, Eltboli, O M I, Lewis, M P, Knox, A J, Aylott, J W, Brightling, C E, Ghaemmaghami, A M, Rose, F R A J

“…Human airway smooth muscle (HASM) contraction plays a central role in regulating airway resistance in both healthy and asthmatic bronchioles. In vitro studies…”
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Conjugatable water-soluble Pt(II) and Pd(II) porphyrin complexes: novel nano- and molecular probes for optical oxygen tension measurement in tissue engineering by Giuntini, F, Chauhan, V M, Aylott, J W, Rosser, G A, Athanasiadis, A, Beeby, A, MacRobert, A J, Brown, R A, Boyle, R W

“…Measurement of oxygen tension in compressed collagen sheets was performed using matrix-embedded optical oxygen sensors based on platinum(II) and palladium(II)…”
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A Real-Time Ratiometric Method for the Determination of Molecular Oxygen Inside Living Cells Using Sol−Gel-Based Spherical Optical Nanosensors with Applications to Rat C6 Glioma by Xu, Hao, Aylott, Jonathan W, Kopelman, Raoul, Miller, Terry J, Philbert, Martin A

“…The first sol−gel-based, ratiometric, optical nanosensors, or sol−gel probes encapsulated by biologically localized embedding (PEBBLEs), are made and…”
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Real-time bacterial detection with an intracellular ROS sensing platform by Hicks, J.M., Halkerston, R., Silman, N., Jackson, S.K., Aylott, J.W., Rawson, F.J.

“…Reactive oxygen species are highly reactive molecules that as well as being ubiquitously expressed throughout the body, are also known to be involved in many…”
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Mass transport of lipopolysaccharide induced H2O2 detected by an intracellular carbon nanoelectrode sensor by Hicks, J.M., Silman, N.J., Jackson, S.K., Aylott, J.W., Rawson, F.J.

“…•Electrochemical sensor detected lipopolysaccharides induced H2O2 within cells.•The mass transport behaviour of H2O2 to the sensor was investigated.•Mass…”
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Development of a SERS strategy to overcome the nanoparticle stabilisation effect in serum-containing samples: Application to the quantification of dopamine in the culture medium of PC-12 cells by Dumont, E., De Bleye, C., Cailletaud, J., Sacré, P.-Y., Van Lerberghe, P.-B., Rogister, B., Rance, G.A., Aylott, J.W., Hubert, Ph, Ziemons, E.

“…The analysis of serum samples by surface-enhanced Raman spectroscopy (SERS) has gained ground over the last few years. However, the stabilisation of colloids…”
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Electrochemical communication with the inside of cells using micro-patterned vertical carbon nanofibre electrodes by Rawson, F. J., Cole, M. T., Hicks, J. M., Aylott, J. W., Milne, W. I., Collins, C. M., Jackson, S. K., Silman, N. J., Mendes, P. M.

“…With the rapidly increasing demands for ultrasensitive biodetection, the design and applications of new nano-scale materials for development of sensors based…”
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Orthogonally bifunctionalised polyacrylamide nanoparticles: a support for the assembly of multifunctional nanodevices by Giuntini, F, Dumoulin, F, Daly, R, Ahsen, V, Scanlan, E M, Lavado, A S P, Aylott, J W, Rosser, G A, Beeby, A, Boyle, R W

“…Polyacrylamide nanoparticles bearing two orthogonal reactive functionalities were prepared by reverse microemulsion polymerisation. Water-soluble…”
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A novel electrospun biphasic scaffold provides optimal three-dimensional topography for in vitro co-culture of airway epithelial and fibroblast cells by Morris, G E, Bridge, J C, Brace, L A, Knox, A J, Aylott, J W, Brightling, C E, Ghaemmaghami, A M, Rose, F R A J

“…Conventional airway in vitro models focus upon the function of individual structural cells cultured in a two-dimensional monolayer, with limited…”
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The delivery of PEBBLE nanosensors to measure the intracellular environment by Webster, A, Coupland, P, Houghton, F D, Leese, H J, Aylott, J W

“…Cellular introduction of PEBBLEs (photonic explorers for bioanalysis with biologically localized embedding) has been investigated by a wide variety of methods…”
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Optical biosensing of nitric oxide using the metalloprotein cytochrome c by Blyth, D J, Aylott, J W, Moir, J W, Richardson, D J, Russell, D A

“…The metalloprotein cytochrome c' was extracted and purified from the bacterium Paracoccus denitrificans in order to develop a specific biosensing system for…”
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A fluorescent PEBBLE nanosensor for intracellular free zinc by Sumner, James P, Aylott, Jonathan W, Monson, Eric, Kopelman, Raoul

“…The development and characterisation of a fluorescent optical PEBBLE (Probe Encapsulated By Biologically Localised Embedding) nanosensor for the detection of…”
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Integrated organic light-emitting device/fluorescence-based chemical sensors by Savvate’ev, V., Chen-Esterlit, Z., Aylott, J. W., Choudhury, B., Kim, C.-H., Zou, L., Friedl, J. H., Shinar, R., Shinar, J., Kopelman, R.

“…A fluorescent chemical sensor platform, integrating an organic light-emitting device (OLED) light-source with a fluorescent probe, is demonstrated for a…”
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Mass transport of lipopolysaccharide induced H 2 O 2 detected by an intracellular carbon nanoelectrode sensor by Hicks, J M, Silman, N J, Jackson, S K, Aylott, J W, Rawson, F J

“…Hydrogen peroxide is a key component of the innate immune response, regulating how a cell responds to a bacterial threat; however, being transient in nature…”
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Protease sensing with nanoparticle based platforms by Welser, Katharina, Adsley, Rosemary, Moore, Bernadette M, Chan, Weng C, Aylott, Jonathan W

“…Nanoparticulate systems in various unique configurations are highly effective at detecting protease activity both in vivo and in vitro. In this article, we…”
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Optical nanosensors--an enabling technology for intracellular measurements by Aylott, Jonathan W

“…Optical nanosensors have been designed to utilise the sensitivity of fluorescence for making quantitative measurements in the intracellular environment, using…”
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Fluorescent nano-PEBBLE sensors designed for intracellular glucose imaging by Xu, Hao, Aylott, Jonathan W, Kopelman, Raoul

“…Polyacrylamide-based, ratiometric, spherical, optical nanosensors, or polyacrylamide PEBBLEs (Probes Encapsulated By Biologically Localized Embedding), have…”
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Optical calcium sensors: development of a generic method for their introduction to the cell using conjugated cell penetrating peptides by Webster, Abigail, Compton, Steven J, Aylott, Jonathan W

“…Probes Encapsulated By Biologically Localised Embedding (PEBBLEs) are optical sensors with nanometer dimensions fabricated by microemulsion polymerisation. The…”
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Optical biosensing of gaseous nitric oxide using spin-coated sol-gel thin films: Sol-gel derived materials by AYLOTT, J. W, RICHARDSON, D. J, RUSSELL, D. A

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Optical Biosensing of Gaseous Nitric Oxide Using Spin-Coated Sol−Gel Thin Films by Aylott, Jonathan W, Richardson, David J, Russell, David A

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