Search Results - "Ayieko, Cyrus"
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Profiling genome-wide recombination in Epstein Barr virus reveals type-specific patterns and associations with endemic-Burkitt lymphoma
Published in Virology journal (08-12-2022)“…Endemic Burkitt lymphoma (eBL) is potentiated through the interplay of Epstein Barr virus (EBV) and holoendemic Plasmodium falciparum malaria. To better…”
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2
Nonsynonymous amino acid changes in the α-chain of complement component 5 influence longitudinal susceptibility to Plasmodium falciparum infections and severe malarial anemia in kenyan children
Published in Frontiers in genetics (14-09-2022)“…Severe malarial anemia (SMA; Hb < 5.0 g/dl) is a leading cause of childhood morbidity and mortality in holoendemic transmission regions such as western Kenya…”
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3
Stabilization of RDT target antigens present in dried Plasmodium falciparum-infected samples for validating malaria rapid diagnostic tests at the point of care
Published in Malaria journal (08-01-2018)“…Malaria rapid diagnostic tests (RDTs) are a great achievement in implementation of parasite based diagnosis as recommended by World Health Organization. A…”
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Changes in B Cell Populations and Merozoite Surface Protein-1-Specific Memory B Cell Responses after Prolonged Absence of Detectable P. falciparum Infection
Published in PloS one (27-06-2013)“…Clinical immunity to malaria declines in the absence of repeated parasite exposure. However, little is known about how B cell populations and antigen-specific…”
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5
Comparison of non-magnetic and magnetic beads multiplex assay for assessment of Plasmodium falciparum antibodies
Published in PeerJ (San Francisco, CA) (03-01-2019)“…New reagents have emerged allowing researchers to assess a growing number of vaccine-associated immune parameters. Multiplex immunoassay(s) are emerging as…”
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Interferon- γ responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission
Published in PeerJ (San Francisco, CA) (2017)“…Malaria elimination campaigns are planned or active in many countries. The effects of malaria elimination on immune responses such as antigen-specific IFN-…”
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Meta-analytic review on the impact of factors that affect performance of malaria rapid diagnostic test in Africa
Published in Journal of health sciences and medicine : (Turkey) (25-03-2024)“…Timely, accurate diagnosis and treatment has improved malaria case management. Malaria Rapid Diagnostic Test (mRDT) kits are largely used in malaria diagnosis…”
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Changes in antigen-specific cytokine and chemokine responses to Plasmodium falciparum antigens in a highland area of Kenya after a prolonged absence of malaria exposure
Published in Infection and immunity (01-09-2014)“…Individuals naturally exposed to Plasmodium falciparum lose clinical immunity after a prolonged lack of exposure. P. falciparum antigen-specific cytokine…”
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Interferon-[gamma] responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission
Published in PeerJ (San Francisco, CA) (10-01-2017)“…Background Malaria elimination campaigns are planned or active in many countries. The effects of malaria elimination on immune responses such as…”
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10
Changes in B Cell Populations and Merozoite Surface Protein-1-Specific Memory B Cell Responses after Prolonged Absence of Detectable P. falciparum Infection. e67230
Published in PloS one (01-06-2013)“…Clinical immunity to malaria declines in the absence of repeated parasite exposure. However, little is known about how B cell populations and antigen-specific…”
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