Search Results - "Ayginin, A. A."

Genomic epidemiology of SARS-CoV-2 in Russia reveals recurring cross-border transmission throughout 2020 by Matsvay, Alina, Klink, Galya V, Safina, Ksenia R, Nabieva, Elena, Garushyants, Sofya K, Biba, Dmitry, Bazykin, Georgii A, Mikhaylov, Ivan M, Say, Anna V, Zakamornaya, Anastasiya I, Khakhina, Anastasiya O, Lisitsa, Tatiana S, Ayginin, Andrey A, Abramov, Ivan S, Bogdan, Sergey A, Kolbutova, Kseniya B, Oleynikova, Daria U, Avdeenko, Tatiana F, Shipulin, German A, Yudin, Sergey M, Skvortsova, Veronika I

“…In 2020, SARS-CoV-2 has spread rapidly across the globe, with most nations failing to prevent or substantially delay its introduction. While many countries…”
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Synthesis and Biological Evaluation of Novel Dispiro -Indolinones with Anticancer Activity by Ivanenkov, Yan A, Kukushkin, Maxim E, Beloglazkina, Anastasia A, Shafikov, Radik R, Barashkin, Alexander A, Ayginin, Andrey A, Serebryakova, Marina S, Majouga, Alexander G, Skvortsov, Dmitry A, Tafeenko, Viktor A, Beloglazkina, Elena K

“…Novel variously substituted thiohydantoin-based -indolinones were prepared using a regio- and diastereoselective synthetic route from…”
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SARS-CoV-2 Recombination and Coinfection Events Identified in Clinical Samples in Russia by Chernyaeva, Ekaterina N, Ayginin, Andrey A, Kosenkov, Alexey V, Romanova, Svetlana V, Tsypkina, Anastasia V, Luparev, Andrey R, Stetsenko, Ivan F, Gnusareva, Natalia I, Matsvay, Alina D, Savochkina, Yulia A, Shipulin, German A

“…Recombination is one of the mechanisms of SARS-CoV-2 evolution along with the occurrence of point mutations, insertions, and deletions. Recently, recombinant…”
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Identification of Novel Antibacterials Using Machine Learning Techniques by Ivanenkov, Yan A, Zhavoronkov, Alex, Yamidanov, Renat S, Osterman, Ilya A, Sergiev, Petr V, Aladinskiy, Vladimir A, Aladinskaya, Anastasia V, Terentiev, Victor A, Veselov, Mark S, Ayginin, Andrey A, Kartsev, Victor G, Skvortsov, Dmitry A, Chemeris, Alexey V, Baimiev, Alexey Kh, Sofronova, Alina A, Malyshev, Alexander S, Filkov, Gleb I, Bezrukov, Dmitry S, Zagribelnyy, Bogdan A, Putin, Evgeny O, Puchinina, Maria M, Dontsova, Olga A

“…Many pharmaceutical companies are avoiding the development of novel antibacterials due to a range of rational reasons and the high risk of failure. However,…”
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Genomic Variability of SARS-CoV-2 Omicron Variant Circulating in the Russian Federation during Early December 2021 and Late January 2022 by Chernyaeva, Ekaterina N, Ayginin, Andrey A, Bulusheva, Irina A, Vinogradov, Kirill S, Stetsenko, Ivan F, Romanova, Svetlana V, Tsypkina, Anastasia V, Matsvay, Alina D, Savochkina, Yulia A, Shipulin, German A

“…Analysis of genomic variability of pathogens associated with heightened public health concerns is an opportunity to track transmission routes of the disease…”
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2-Pyrazol-1-yl-thiazole derivatives as novel highly potent antibacterials by Ivanenkov, Yan A., Yamidanov, Renat S., Osterman, Ilya A., Sergiev, Petr V., Aladinskiy, Vladimir A., Aladinskaya, Anastasia V., Terentiev, Victor A., Veselov, Mark S., Ayginin, Andrey A., Skvortsov, Dmitry A., Komarova, Katerina S., Sadovnikov, Sergey V., Matniyazov, Rustam, Sofronova, Alina A., Malyshev, Alexander S., Machulkin, Alexey E., Petrov, Rostislav A., Lukianov, Dmitrii, Iarovenko, Svetlana, Bezrukov, Dmitry S., Baymiev, Andrey Kh, Dontsova, Olga A.

“…The present report describes our efforts to identify new structural classes of compounds having promising antibacterial activity using previously published…”
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Development and Testing of the Method for the Detection of Lassa virus RNA, Based on real-Time Polymerase Chain reaction with reverse Transcription by Dedkov, V. G., Safonova, M. V., Naidenova, E. V., Magassouba, N. F., Ayginin, A. A., Soropogui, B., Kourouma, F., Camara, A. B., Camara, J., Kritsky, A. A., Shchelkanov, M. Yu, Maleev, V. V.

“…Objective of the study was the development of a method for the detection and quantitative analysis (realtime RT-PCR) to identify genetic markers of Lassa virus…”
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The Study of Viral RNA Diversity in Bird Samples Using De Novo Designed Multiplex Genus-Specific Primer Panels by Khafizov, Kamil, Shipulin, German A., Artyushin, Ilya V., Blinova, Ekaterina A., Safonova, Marina V., Speranskaya, Anna S., Matsvay, Alina D., Pimkina, Ekaterina V., Ayginin, Andrey A., Dedkov, Vladimir G.

“…Advances in the next generation sequencing (NGS) technologies have significantly increased our ability to detect new viral pathogens and systematically…”
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Development and Evaluation of a One-Step Quantitative RT-PCR Assay for Detection of Lassa Virus by Dedkov, Vladimir G., Magassouba, N.’Faly, Safonova, Marina V., Naydenova, Ekaterina V., Ayginin, Andrey A., Soropogui, Barre, Kourouma, Fode, Camara, Amara B., Camara, Jacob, Kritzkiy, Andrey A., Tuchkov, Igor V., Shchelkanov, Mikhail Yu, Maleev, Victor V.

“…•LASV RT-qPCR diagnostic sensitivity was 96.4% & specificity 100%.•Limit of detection ranged from 103- 105copies/ml with lineages I-IV.•Assay can be used with…”
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Small-molecule inhibitors of hepatitis C virus (HCV) non-structural protein 5A (NS5A): a patent review (2010-2015) by Ivanenkov, Yan A, Aladinskiy, Vladimir A, Bushkov, Nikolay A, Ayginin, Andrey A, Majouga, Alexander G, Ivachtchenko, Alexandre V

“…Non-structural 5A (NS5A) protein has achieved a considerable attention as an attractive target for the treatment of hepatitis C (HCV). A number of novel NS5A…”
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Improved Protocols of ITS1-Based Metabarcoding and Their Application in the Analysis of Plant-Containing Products by Omelchenko, Denis O, Speranskaya, Anna S, Ayginin, Andrey A, Khafizov, Kamil, Krinitsina, Anastasia A, Fedotova, Anna V, Pozdyshev, Denis V, Shtratnikova, Viktoria Y, Kupriyanova, Evgenia V, Shipulin, German A, Logacheva, Maria D

“…Plants are widely used for food and beverage preparation, most often in the form of complex mixtures of dried and ground parts, such as teas, spices or herbal…”
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Sequencing and genetic characterization of two strains Paramushir virus obtained from the Tyuleniy Island in the Okhotsk Sea (2015) by Safonova, Marina V., Shchelkanov, Mikhail Yu, Khafizov, Kamil, Matsvay, Alina D., Ayginin, Andrey A., Dolgova, Anna S., Shchelkanov, Egor M., Pimkina, Ekaterina V., Speranskaya, Anna S., Galkina, Irina V., Dedkov, Vladimir G.

“…Paramushir virus belongs to Sakhalin virus genogroup within Orthonairovirus genus and is one of the poorly studied viruses with unknown pathogenicity. At the…”
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Identification of pyrrolo-pyridine derivatives as novel class of antibacterials by Veselov, Mark S., Ivanenkov, Yan A., Yamidanov, Renat S., Osterman, Ilya A., Sergiev, Petr V., Aladinskiy, Vladimir A., Aladinskaya, Anastasia V., Terentiev, Victor A., Ayginin, Andrey A., Skvortsov, Dmitry A., Komarova, Katerina S., Chemeris, Alexey V., Baimiev, Alexey Kh, Sofronova, Alina A., Machulkin, Alexey E., Petrov, Rostislav A., Maklakova, Svetlana Yu, Bezrukov, Dmitry S., Filkov, Gleb I., Zainullina, Liana F., Maximova, Marina A., Zileeva, Zulfiya R., Kartsev, Victor G., Vakhitova, Yulia V., Dontsova, Olga A.

“…A series of 5-oxo-4 H -pyrrolo[3,2-b]pyridine derivatives was identified as novel class of highly potent antibacterial agents during an extensive large-scale…”
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NGS sequencing as an efficient instrument of molecular genetic diagnostics in patients with chronic pancreatitis by Khafizov, Kamil F., Litvinova, Mariya M., Ayginin, Andrei A., Matsvay, Alina D., Pimkina, Ekaterina V., Speranskaya, Anna S., Shipulin, German A., Vinokurova, Ludmila V., Nikolskaya, Karine A., Dubtsova, Elena A., Bordin, Dmitry S.

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Comparative analysis of Illumina and Ion Torrent high-throughput sequencing platforms for identification of plant components in herbal teas by Speranskaya, Anna S., Khafizov, Kamil, Ayginin, Andrey A., Krinitsina, Anastasia A., Omelchenko, Denis O., Nilova, Maya V., Severova, Elena E., Samokhina, Evgeniya N., Shipulin, German A., Logacheva, Maria D.

“…The rapid development of high-throughput sequencing (HTS) methods offers new opportunities for food quality control and identification of food components using…”
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Synthesis and Biological Evaluation of Novel IDispiro/I-Indolinones with Anticancer Activity by Ivanenkov, Yan A, Kukushkin, Maxim E, Beloglazkina, Anastasia A, Shafikov, Radik R, Barashkin, Alexander A, Ayginin, Andrey A, Serebryakova, Marina S, Majouga, Alexander G, Skvortsov, Dmitry A, Tafeenko, Viktor A, Beloglazkina, Elena K

“…Novel variously substituted thiohydantoin-based dispiro-indolinones were prepared using a regio- and diastereoselective synthetic route from…”
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