Search Results - "Aye, C"

Effect of economic growth on CO2 emission in developing countries: Evidence from a dynamic panel threshold model by Aye, Goodness C, Edoja, Prosper Ebruvwiyo

“…This study investigated the effect of economic growth on CO2 emission using the dynamic panel threshold framework. The analysis is based on data from a panel…”
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The structure of an Hsp90-immunophilin complex reveals cochaperone recognition of the client maturation state by Lee, Kanghyun, Thwin, Aye C., Nadel, Cory M., Tse, Eric, Gates, Stephanie N., Gestwicki, Jason E., Southworth, Daniel R.

“…The Hsp90 chaperone promotes folding and activation of hundreds of client proteins in the cell through an ATP-dependent conformational cycle guided by distinct…”
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Cryptococcosis—the impact of delay to diagnosis by Aye, C., Henderson, A., Yu, H., Norton, R.

“…Cryptococcosis is a mycotic disease caused by the yeast Cryptococcus sp. It is associated with significant mortality and morbidity, including long-term…”
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Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP by Nadel, Cory M., Pokhrel, Saugat, Wucherer, Kristin, Oehler, Abby, Thwin, Aye C., Basu, Koli, Callahan, Matthew D., Southworth, Daniel R., Mordes, Daniel A., Craik, Charles S., Gestwicki, Jason E.

“…Microtubule-associated protein tau (MAPT/tau) accumulates in a family of neurodegenerative diseases, including Alzheimer’s disease (AD). In disease, tau is…”
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Adverse perinatal outcomes are strongly associated with degree of abnormality in uterine artery Doppler pulsatility index by Dockree, S., Aye, C., Ioannou, C., Cavallaro, A., Black, R., Impey, L.

“…ABSTRACT Objective To investigate the association between varying degrees of abnormality in the Doppler uterine artery pulsatility index (UtA‐PI) and adverse…”
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The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions by Braxton, Julian R., Altobelli, Chad R., Tucker, Maxwell R., Tse, Eric, Thwin, Aye C., Arkin, Michelle R., Southworth, Daniel R.

“…p97, also known as valosin-containing protein, is an essential cytosolic AAA+ (ATPases associated with diverse cellular activities) hexamer that unfolds…”
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Technical efficiency of provincial public healthcare in South Africa by Ngobeni, Victor, Breitenbach, Marthinus C, Aye, Goodness C

“…Forty-nine million people or 83 per cent of the entire population of 59 million rely on the public healthcare system in South Africa. Coupled with a shortage…”
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The E3 Ubiquitin Ligase, CHIP/STUB1, Inhibits Aggregation of Phosphorylated Proteoforms of Microtubule-associated Protein Tau (MAPT) by Nadel, Cory M., Thwin, Aye C., Callahan, Matthew, Lee, Kanghyun, Connelly, Emily, Craik, Charles S., Southworth, Daniel R., Gestwicki, Jason E.

“…[Display omitted] •CHIP binds more tightly to phosphorylated tau (p-tau) than unmodified tau.•CHIP suppresses p-tau aggregation and rapidly ubiquitinates it in…”
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Causality between economic policy uncertainty and real housing returns in emerging economies: A cross-sample validation approach by Aye, Goodness C

“…This paper examines whether economic policy uncertainty (EPU) causes real housing returns in 8 emerging economies for which EPU data are available namely:…”
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Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis by Lopez, Kyle E., Rizo, Alexandrea N., Tse, Eric, Lin, JiaBei, Scull, Nathaniel W., Thwin, Aye C., Lucius, Aaron L., Shorter, James, Southworth, Daniel R.

“…The ClpAP complex is a conserved bacterial protease that unfolds and degrades proteins targeted for destruction. The ClpA double-ring hexamer powers substrate…”
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Chemical Features of Polyanions Modulate Tau Aggregation and Conformational States by Montgomery, Kelly M., Carroll, Emma C., Thwin, Aye C., Quddus, Athena Y., Hodges, Paige, Southworth, Daniel R., Gestwicki, Jason E.

“…The aggregation of tau into insoluble fibrils is a defining feature of neurodegenerative tauopathies. However, tau has a positive overall charge and is highly…”
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Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking by Schuller, Marion, Correy, Galen J, Gahbauer, Stefan, Fearon, Daren, Wu, Taiasean, Díaz, Roberto Efraín, Young, Iris D, Carvalho Martins, Luan, Smith, Dominique H, Schulze-Gahmen, Ursula, Owens, Tristan W, Deshpande, Ishan, Merz, Gregory E, Thwin, Aye C, Biel, Justin T, Peters, Jessica K, Moritz, Michelle, Herrera, Nadia, Kratochvil, Huong T, Aimon, Anthony, Bennett, James M, Brandao Neto, Jose, Cohen, Aina E, Dias, Alexandre, Douangamath, Alice, Dunnett, Louise, Fedorov, Oleg, Ferla, Matteo P, Fuchs, Martin R, Gorrie-Stone, Tyler J, Holton, James M, Johnson, Michael G, Krojer, Tobias, Meigs, George, Powell, Ailsa J, Rack, Johannes Gregor Matthias, Rangel, Victor L, Russi, Silvia, Skyner, Rachael E, Smith, Clyde A, Soares, Alexei S, Wierman, Jennifer L, Zhu, Kang, O'Brien, Peter, Jura, Natalia, Ashworth, Alan, Irwin, John J, Thompson, Michael C, Gestwicki, Jason E, von Delft, Frank, Shoichet, Brian K, Fraser, James S, Ahel, Ivan

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain within the nonstructural protein 3 counteracts host-mediated antiviral adenosine…”
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Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations by Tsutakawa, Susan E., Sarker, Altaf H., Ng, Clifford, Arvai, Andrew S., Shin, David S., Shih, Brian, Jiang, Shuai, Thwin, Aye C., Tsai, Miaw-Sheue, Willcox, Alexandra, Her, Mai Zong, Trego, Kelly S., Raetz, Alan G., Rosenberg, Daniel, Bacolla, Albino, Hammel, Michal, Griffith, Jack D., Cooper, Priscilla K., Tainer, John A.

“…Xeroderma pigmentosum group G (XPG) protein is both a functional partner in multiple DNA damage responses (DDR) and a pathway coordinator and…”
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Global Healthcare Resource Efficiency in the Management of COVID-19 Death and Infection Prevalence Rates by Breitenbach, Marthinus C, Ngobeni, Victor, Aye, Goodness C

“…The scale of impact of the COVID-19 pandemic on society and the economy globally provides a strong incentive to thoroughly analyze the efficiency of healthcare…”
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Dynamic relationship among CO2 emission, agricultural productivity and food security in Nigeria by Edoja, Prosper Ebruvwiyo, Aye, Goodness C, Abu, Orefi

“…The study analyzed the dynamic relationship among CO2 emission (CE), agricultural productivity (AGP), and food security (FS) in Nigeria. The study used annual…”
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Dynamic effect of fiscal policy on wealth inequality: Evidence from middle-income countries by Aye, Goodness C, Odhiambo, Nicholas M

“…The study examined the dynamic effect of fiscal policy on wealth inequality in middle-income countries using panel data from 2010 to 2018 and the system…”
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Impact of free-living pattern of sedentary behaviour on intra-day glucose regulation in type 2 diabetes by Paing, Aye C., McMillan, Kathryn A., Kirk, Alison F., Collier, Andrew, Hewitt, Allan, Chastin, Sebastien F. M.

“…Purpose To investigate how the pattern of sedentary behaviour affects intra-day glucose regulation in type 2 diabetes. Methods This intensive longitudinal…”
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Dose-response between frequency of breaks in sedentary time and glucose control in type 2 diabetes: A proof of concept study by Paing, Aye C., McMillan, Kathryn A., Kirk, Alison F., Collier, Andrew, Hewitt, Allan, Chastin, Sebastien F.M.

“…This study aimed to investigate dose-response between frequency of breaks in sedentary time and glucose control. Randomised three-treatment, two-period…”
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Diurnal patterns of objectively measured sedentary time and interruptions to sedentary time are associated with glycaemic indices in type 2 diabetes by Paing, Aye C., McMillan, Kathryn A., Kirk, Alison F., Collier, Andrew, Hewitt, Allan, Dunstan, David, Owen, Neville, Chastin, Sebastien F.M.

“…To investigate diurnal patterns of sedentary time and interruptions to sedentary time and their associations with achievement of pre-meal glucose, post-meal…”
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Are glucose profiles well-controlled within the targets recommended by the International diabetes Federation in type 2 diabetes? A meta-analysis of results from continuous glucose monitoring based studies by Paing, Aye C., Kirk, Alison F., Collier, Andrew, Kubiak, Thomas, Chastin, Sebastien F.M.

“…To assess continuous glucose monitoring (CGM) derived intra-day glucose profiles using global guideline for type 2 diabetes recommended by the International…”
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