Search Results - "Ayasolla, Kamesh"

Lipid peroxidation products as predictors of oxidant-mediated disease in preterm infants by Katti, Karishma, Ayasolla, Kamesh R., Iurcotta, Toni, Potak, Debra, Codipilly, Champa, Weinberger, Barry

“…Preterm infants are susceptible to "oxygen radical diseases" (ORD). 8-isoprostane (8-IP) is a bioactive eicosanoid generated by reactive oxygen…”
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Galantamine ameliorates hyperoxia-induced brain injury in neonatal mice by Zaghloul, Nahla, Cohen, Naomi S, Ayasolla, Kamesh R, Li, Hsiu-Ling, Kurepa, Dalibor, Ahmed, Mohamed N

“…Prolonged oxygen therapy in preterm infants often leads to cognitive impairment. Hyperoxia leads to excess free radical production with subsequent…”
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Forebrain Cholinergic Dysfunction and Systemic and Brain Inflammation in Murine Sepsis Survivors by Zaghloul, Nahla, Addorisio, Meghan E, Silverman, Harold A, Patel, Hardik L, Valdés-Ferrer, Sergio I, Ayasolla, Kamesh R, Lehner, Kurt R, Olofsson, Peder S, Nasim, Mansoor, Metz, Christine N, Wang, Ping, Ahmed, Mohamed, Chavan, Sangeeta S, Diamond, Betty, Tracey, Kevin J, Pavlov, Valentin A

“…Sepsis, a complex disorder characterized by immune, metabolic, and neurological dysregulation, is the number one killer in the intensive care unit. Mortality…”
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Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton by Kumar, Vinod, Paliwal, Nitpriya, Ayasolla, Kamesh, Vashistha, Himanshu, Jha, Alok, Chandel, Nirupama, Chowdhary, Sheetal, Saleem, Moin A., Malhotra, Ashwani, Chander, Praveen N., Skorecki, Karl, Singhal, Pravin C.

“…APOL1-miR193a axis participates in the preservation of molecular phenotype of differentiated podocytes (DPDs). We examined the hypothesis that APOL1 (G0)…”
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MIF inhibition enhances pulmonary angiogenesis and lung development in congenital diaphragmatic hernia by Perveen, Shahana, Ayasolla, Kamesh, Zagloul, Nahla, Patel, Hardik, Ochani, Kanta, Orner, David, Benveniste, Helene, Salerno, Michael, Vaska, Paul, Zuo, Zhang, Alabed, Yousef, Nasim, Mansoor, Miller, Edmund J., Ahmed, Mohamed

“…Background Congenital diaphragmatic hernia (CDH) is a complex birth anomaly with significant mortality and morbidity. Lung hypoplasia and persistent pulmonary…”
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Correction: MIF inhibition enhances pulmonary angiogenesis and lung development in congenital diaphragmatic hernia by Perveen, Shahana, Ayasolla, Kamesh, Zagloul, Nahla, Patel, Hardik, Ochani, Kanta, Orner, David, Benveniste, Helene, Salerno, Michael, Vaska, Paul, Zuo, Zhang, Alabed, Yousef, Nasim, Mansoor, Miller, Edmund J., Ahmed, Mohamed

“…In the original version of this article, the name of the author “Kamesh Ayasolla” was incorrectly given as “Kamesh Ayyasola”. This has now been corrected to…”
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MiR193a Modulation and Podocyte Phenotype by Jha, Alok, Saha, Shourav, Ayasolla, Kamesh, Vashistha, Himanshu, Malhotra, Ashwani, Skorecki, Karl, Singhal, Pravin C

“…Apolipoprotein L1 (APOL1)-miR193a axis has been reported to play a role in the maintenance of podocyte homeostasis. In the present study, we analyzed…”
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Multifunctional Cyclic d,l‑α-Peptide Architectures Stimulate Non-Insulin Dependent Glucose Uptake in Skeletal Muscle Cells and Protect Them Against Oxidative Stress by Shapira, Renana, Rudnick, Safra, Daniel, Bareket, Viskind, Olga, Aisha, Vered, Richman, Michal, Ayasolla, Kamesh R, Perelman, Alex, Chill, Jordan H, Gruzman, Arie, Rahimipour, Shai

“…Oxidative stress directly correlates with the early onset of vascular complications and the progression of peripheral insulin resistance in diabetes…”
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mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN by Rai, Partab, Plagov, Andrei, Lan, Xiqian, Chandel, Nirupama, Singh, Tejinder, Lederman, Rivka, Ayasolla, Kamesh R, Mathieson, Peter W, Saleem, Moin A, Husain, Mohammad, Malhotra, Ashwani, Chander, Praveen N, Singhal, Pravin C

“…Oxidative stress has been implicated to contribute to HIV-induced kidney cell injury; however, the role of p53, a modulator of oxidative stress, has not been…”
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Tubular cell phenotype in HIV-associated nephropathy: Role of phospholipid lysophosphatidic acid by Ayasolla, Kamesh R., Rai, Partab, Rahimipour, Shai, Hussain, Mohammad, Malhotra, Ashwani, Singhal, Pravin C.

“…Collapsing glomerulopathy and microcysts are characteristic histological features of HIV-associated nephropathy (HIVAN). We have previously reported the role…”
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AT1R blockade in adverse milieus: role of SMRT and corepressor complexes by Singh, Tejinder, Ayasolla, Kamesh, Rai, Partab, Chandel, Nirupama, Haque, Shabirul, Lederman, Rivka, Husain, Mohammad, Vethantham, Vasupradha, Chawla, Amrita, Vashistha, Himanshu, Saleem, Moin A, Ding, Guohua, Chander, Praveen N, Malhotra, Ashwani, Meggs, Leonard G, Singhal, Pravin C

“…ANG II type 1 receptor blockade (AT1R-BLK) is used extensively to slow down the progression of proteinuric kidney diseases. We hypothesized that AT1R-BLK…”
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5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia by Ayasolla, Kamesh R, Giri, Shailendra, Singh, Avtar K, Singh, Inderjit

“…BACKGROUND: Alzheimer's disease (AD) pathology shows characteristic 'plaques' rich in amyloid beta (Aβ) peptide deposits. Inflammatory process-related proteins…”
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Rapamycin-induced modulation of HIV gene transcription attenuates progression of HIVAN by Rai, Partab, Plagov, Andrei, Kumar, Dileep, Pathak, Shresh, Ayasolla, Kamesh R., Chawla, Amrita K., Mathieson, Peter W., Saleem, Moin A., Husain, Mohammad, Malhotra, Ashwani, Singhal, Pravin C.

“…HIV-associated nephropathy (HIVAN) is the manifestation of HIV gene expression by kidney cells in the presence of specific host factors. Recently, rapamycin…”
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KLVFF-surface-modified Protein Microspheres For Potential Diagnostics And Therapeutics In Alzheimer's Disease (AD) by Richman, Michal, Ayasolla, Kamesh R, Rahimipour, Shai

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Alterations in plasma membrane ion channel structures stimulate NLRP3 inflammasome activation in APOL1 risk milieu by Jha, Alok, Kumar, Vinod, Haque, Shabirul, Ayasolla, Kamesh, Saha, Shourav, Lan, Xiqian, Malhotra, Ashwani, Saleem, Moin A., Skorecki, Karl, Singhal, Pravin C.

“…We evaluated alterations in the structural configurations of channels and activation of nucleotide‐binding domain, leucine‐rich‐containing family, pyrin…”
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Disrupted apolipoprotein L1-miR193a axis dedifferentiates podocytes through autophagy blockade in an APOL1 risk milieu by Kumar, Vinod, Ayasolla, Kamesh, Jha, Alok, Mishra, Abheepsa, Vashistha, Himanshu, Lan, Xiqian, Qayyum, Maleeha, Chinnapaka, Sushma, Purohit, Richa, Mikulak, Joanna, Saleem, Moin A, Malhotra, Ashwani, Skorecki, Karl, Singhal, Pravin C

“…We hypothesized that a functional apolipoprotein LI (APOL1)-miR193a axis (inverse relationship) preserves, but disruption alters, the podocyte molecular…”
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Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition by Kumar, Vinod, Vashistha, Himanshu, Lan, Xiqian, Chandel, Nirupama, Ayasolla, Kamesh, Shoshtari, Seyedeh Shadafarin Marashi, Aslam, Rukhsana, Paliwal, Nitpriya, Abbruscato, Frank, Mikulak, Joanna, Popik, Waldemar, Atta, Mohamed G., Chander, Praveen N., Malhotra, Ashwani, Meyer-Schwesinger, Catherine, Skorecki, Karl, Singhal, Pravin C.

“…Human parietal epithelial cells (PECs) are progenitor cells that sustain podocyte homeostasis. We hypothesized that the lack of apolipoprotein (APO) L1 ensures…”
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Alterations in Plasma Membrane Ion Channel Structures Stimulate NLRP3 Inflammasomes Activation in APOL1 Risk Milieu by Jha, Alok, Kumar, Vinod, Haque, Shabirul, Ayasolla, Kamesh, Saha, Shourav, Lan, Xiqian, Malhotra, Ashwani, Saleem, Moin A., Skorecki, Karl, Singhal, Pravin C.

“…We evaluated alterations in the structural configurations of channels and activation of NLRP3 inflammasomes formation in APOL1 risk and non-risk milieus…”
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Vitamin D receptor deficit induces activation of renin angiotensin system via SIRT1 modulation in podocytes by Chandel, Nirupama, Ayasolla, Kamesh, Wen, Hongxiu, Lan, Xiqian, Haque, Shabirul, Saleem, Moin A., Malhotra, Ashwani, Singhal, Pravin C.

“…Vitamin D receptor (VDR) deficient status has been shown to be associated with the activation of renin angiotensin system (RAS). We hypothesized that lack of…”
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Renin modulates HIV replication in T cells by Chandel, Nirupama, Ayasolla, Kamesh, Lan, Xiqian, Rai, Partab, Mikulak, Joanna, Husain, Mohammad, Malhotra, Ashwani, McGowan, Joseph, Singhal, Pravin C.

“…Renin contributes to HIV replication in T cells via (P) RRPLZF signaling cascade and cleavage of Gag polyproteins. HIV is known to subvert cellular machinery…”
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