Search Results - "Ayas, Najib"
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Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis
Published in The lancet respiratory medicine (01-08-2019)“…There is a scarcity of published data on the global prevalence of obstructive sleep apnoea, a disorder associated with major neurocognitive and cardiovascular…”
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Intermittent hypoxia causes histological kidney damage and increases growth factor expression in a mouse model of obstructive sleep apnea
Published in PloS one (01-02-2018)“…Epidemiological studies demonstrate an association between obstructive sleep apnea (OSA) and accelerated loss of kidney function. It is unclear whether the…”
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Will This Hemodynamically Unstable Patient Respond to a Bolus of Intravenous Fluids?
Published in JAMA : the journal of the American Medical Association (27-09-2016)“…IMPORTANCE: Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable…”
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New-Onset Hypertension and Sodium Oxybate—Something to Think About
Published in Mayo Clinic proceedings (01-11-2024)Get full text
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Revolutionising obstructive sleep apnoea therapy: polysomnography unveils hidden clues to help provide precision care
Published in The European respiratory journal (01-06-2024)Get more information
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Cardiovascular Events in Obstructive Sleep Apnea — Can CPAP Therapy SAVE Lives?
Published in The New England journal of medicine (08-09-2016)“…Obstructive sleep apnea is a common disorder that has been associated with an increased risk of cardiovascular disease. 1 Continuous positive airway pressure…”
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Diagnosis and treatment of obstructive sleep apnea in adults
Published in Canadian Medical Association journal (CMAJ) (04-12-2017)“…Obstructive sleep apnea (OSA) is characterized by recurring episodes of cessation (apnea) or reduction (hypopnea) in airflow during sleep caused by obstruction…”
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Metrics of sleep apnea severity: beyond the apnea-hypopnea index
Published in Sleep (New York, N.Y.) (01-07-2021)“…Abstract Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA has well established cardiovascular and neurocognitive…”
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The Baby, the Bathwater, and the Polysomnogram
Published in American journal of respiratory and critical care medicine (01-08-2020)“…Malhotra and Ayas discuss the article by Donovan and Patel on the utility of the polysomnogram (PSG). They state that they are also strong believers in…”
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An Official American Thoracic Society Statement: The Importance of Healthy Sleep. Recommendations and Future Priorities
Published in American journal of respiratory and critical care medicine (15-06-2015)“…Despite substantial public interest, few recommendations on the promotion of good sleep health exist to educate health care providers and the general public on…”
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Obstructive Sleep Apnea and Kidney Disease: A Potential Bidirectional Relationship?
Published in Journal of clinical sleep medicine (15-08-2015)“…Chronic kidney disease (CKD) is associated with high mortality rates and heavy economic and social burdens. Nearly 10% of the United States population suffer…”
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Restricting resident work hours: The good, the bad, and the ugly
Published in Critical care medicine (01-03-2012)“…OBJECTIVES:Inadequate sleep and long work hours are long-standing traditions in the medical profession, and work schedules are especially intense in resident…”
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Sleep Study and Oximetry Parameters for Predicting Postoperative Complications in Patients With OSA
Published in Chest (01-04-2019)“…In the surgical setting, OSA is associated with an increased risk of postoperative complications. At present, risk stratification using OSA-associated…”
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The antioxidant α-lipoic acid attenuates intermittent hypoxia-related renal injury in a mouse model of sleep apnea
Published in Sleep (New York, N.Y.) (11-06-2019)“…Oxidative stress and inflammation are proposed to mediate kidney diseases that occur in patients with obstructive sleep apnea (OSA). We examined the hypothesis…”
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Circulating levels of cell adhesion molecules and risk of cardiovascular events in obstructive sleep apnea
Published in PloS one (30-07-2021)“…Background Obstructive sleep apnea (OSA) patients are at increased risk of cardiovascular disease (CVD). Cell adhesion molecules (CAM) are increased in OSA and…”
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Impact of extended-duration shifts on medical errors, adverse events, and attentional failures
Published in PLoS medicine (01-12-2006)“…A recent randomized controlled trial in critical-care units revealed that the elimination of extended-duration work shifts (> or =24 h) reduces the rates of…”
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A portrait of obstructive sleep apnea risk factors in 27,210 middle-aged and older adults in the Canadian Longitudinal Study on Aging
Published in Scientific reports (24-03-2022)“…Determining the prevalence and characteristics of individuals susceptible to present with obstructive sleep apnea (OSA) is essential for developing targeted…”
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One-Year Outcomes in Caregivers of Critically Ill Patients
Published in The New England journal of medicine (12-05-2016)“…Investigators evaluated the caregivers of patients who had received mechanical ventilation for at least 7 days in an ICU. Although there was a large burden of…”
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Could Adjunctive Pharmacology Mitigate Cardiovascular Consequences of Obstructive Sleep Apnea?
Published in American journal of respiratory and critical care medicine (01-09-2019)“…[...]no randomized controlled trial to date has documented a significant reduction in cardiovascular events when OSA is treated by continuous positive airway…”
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Diagnosis and initial management of obstructive sleep apnea without polysomnography: a randomized validation study
Published in Annals of internal medicine (06-02-2007)“…Polysomnography (PSG), despite limited availability and high cost, is currently recommended for diagnosis of obstructive sleep apnea and titration of effective…”
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