Search Results - "Ayari, Sameh"
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Prognostic impact of immune status and hematopoietic recovery before and after fludarabine, IV busulfan, and antithymocyte globulins (FB2 regimen) reduced-intensity conditioning regimen (RIC) allogeneic stem cell transplantation (allo-SCT)
Published in European journal of haematology (01-03-2013)“…This retrospective analysis aimed to assess hematopoietic and immune recovery in a cohort of 53 patients [males: n = 33; median age: 59 yr (range: 22–70)] who…”
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Long-Lasting HHV-6 Reactivation in Long-Term Adult Survivors After Double Umbilical Cord Blood Allogeneic Stem Cell Transplantation
Published in The Journal of infectious diseases (15-08-2014)“…Higher incidence of human herpesvirus 6 (HHV-6) infection has been documented after umbilical cord blood allotransplant in adults. Here we demonstrate that…”
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Human herpesvirus 6 reactivation before engraftment is strongly predictive of graft failure after double umbilical cord blood allogeneic stem cell transplantation in adults
Published in Experimental hematology (01-11-2014)“…Our main objective was to determine new factors associated with engraftment and single-unit predominance after double umbilical cord blood (UCB) allogeneic…”
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Prolonged Fluconazole Prophylaxis Is Not Required In Patients With Acute Leukemias Or Myelodysplastic/Myeloproliferative Disorders After Reduced-Intensity Conditioning (RIC) Allogeneic Stem Cell Transplantation (allo-SCT): A Pair-Matched Analysis
Published in Blood (15-11-2013)“…Invasive fungal infections (IFI) due to Candida and Aspergillus species remain a major complication of allo-SCT. In the myeloablative setting, previous studies…”
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Immunomodulation by Lymphodepletion and Donor Lymphocyte Infusion to Treat Post Allogeneic Transplantation Relapse
Published in Blood (19-11-2010)“…Abstract 2084 Relapse of hematologic malignancies following allogeneic hematopoietic stem cell transplantation (HSCT) remains a major cause of treatment…”
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Initial fluconazole prophylaxis may not be required in adults with acute leukemia or myelodysplastic/myeloproliferative disorders after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation
Published in Annals of hematology (01-04-2015)“…In the myeloablative transplant setting, the early use of fluconazole prophylaxis provides a benefit in overall survival. Recent changes in transplantation…”
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Is ASCT With TBI Superior to ASCT Without TBI in Mantle Cell Lymphoma Patients?
Published in Transplantation (15-08-2012)“…Impact of total-body irradiation (TBI) in conditioning regimen on outcome for patients with mantle cell lymphoma (MCL) remains unknown. Patients with MCL who…”
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Rituximab for the treatment of adult relapsed/refractory CD20 positive B-ALL patients: A pilot series
Published in Leukemia research (01-03-2012)“…Abstract No series have reported the results of the use of the therapeutic anti-CD20 monoclonal antibody (Rituximab) in the setting of adult…”
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Escalated lymphodepletion Followed by Donor Lymphocyte Infusion (DLI) can Induce a Graft-Versus-Host Response without Overwhelming Toxicity
Published in Blood (20-11-2009)“…Abstract 3033 Poster Board II-1009▪▪This icon denotes an abstract that is clinically relevant. Donor lymphocyte infusion (DLI) approach alone for treatment of…”
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Allogeneic Stem Cell Transplantation (allo-SCT) for Secondary Acute Myeloid Leukemia (AML) Following Breast Carcinoma
Published in Blood (20-11-2009)“…Abstract 3305 Poster Board III-193▪▪This icon denotes an abstract that is clinically relevant. Patients with breast carcinoma who received Radio and/or…”
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Long-Term Complications (LTC) and Quality of Life (QOL) After Reduced-Intensity Conditioning (RIC) Allogeneic Stem Cell Transplantation (allo-SCT)
Published in Blood (18-11-2011)“…Abstract 4100 RIC allo-SCT is increasingly used in elderly or frail patients not eligible for myeloablative conditioning. While the natural history of LTC and…”
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5-Azacytidine (AZA) Compared to Intensive Chemotherapy in Elderly Acute Myeloid Leukemia (AML) Patients: Results of a Retrospective Single Centre Matched Analysis
Published in Blood (18-11-2011)“…Abstract 3620 AML in elderly patients is characterized by a poor prognosis, especially in those patients aged >70, and/or in frail patients with comorbidities…”
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Prognostic Impact of Hematopoietic Recovery After Fludarabine, IV Busulfan and Antithymocyte Globulins (FB2 regimen) Reduced-Intensity Conditioning Regimen (RIC) Allogeneic Stem Cell Transplantation (allo-SCT)
Published in Blood (16-11-2012)“…Abstract 4483 RIC regimens are increasingly used prior to allo-SCT. The FB2 regimen (Fludarabine 120–150 mg/m2 + IV Busulfan 6.4 mg/Kg + ATG Thymoglobuline…”
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Comparison of PBSC Vs Cord Blood (CB) As Stem Cells Source for Reduced-Intensity Conditioning Regimen (RIC) Allogeneic Stem Cell Transplantation (allo-SCT) in Adult Patients with Haematological Diseases: A Single Centre Analysis
Published in Blood (16-11-2012)“…Abstract 3108 RIC regimens are increasingly used for allo-SCT in older patients or patients with co-morbidities. The FB2 regimen (Fludarabine 120–150 mg/m2 +…”
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Fludarabine, Low Dose Busulfan and Antithymocyte Globulin (ATG) Compared to Fludarabine and Low Dose Total Body Irradiation (TBI) for Reduced-Intensity Conditioning (RIC) Prior to Allogeneic Stem Cell Transplantation (allo-SCT) In Patients with Lymphoid Malignancies
Published in Blood (19-11-2010)“…Abstract 3472 Allo-SCT procedures are currently undergoing a profound evolution. The spectra of patients and diseases for which this approach is now considered…”
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Autologous Stem Cell Transplantation In Mantle Cell Lymphoma: Total Body Irradiation (TBI) Plus Cyclophosphamide (or Melphalan) Is Not Superior to BEAM, A Single Institution Experience
Published in Blood (19-11-2010)“…Abstract 3563 Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin's lymphoma (NHL) characterized by overexpression of cyclin D1 as a result of the…”
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A Scoring System Predictive of Extensive Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Stem Cell Transplantation (allo-SCT)
Published in Blood (18-11-2011)“…Abstract 1980 Chronic GVHD is one of the most serious consequences of allo-SCT associated with high morbidity and mortality. Therefore, identification of…”
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5-Azacytidine (5-AZA) Salvage Therapy for Very High Risk Acute Myeloid Leukemia (AML): Response After 3 Cycles Is the Major Determinant for Outcome
Published in Blood (20-11-2009)“…Abstract 2044 Poster Board II-21 Very high risk AML can be categorized into three groups: i) group I: AML in second relapse or refractory after 2 induction…”
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Reduced-intensity conditioning allogeneic stem cell transplant for relapsed or transformed aggressive B-cell non-Hodgkin lymphoma
Published in Leukemia & lymphoma (01-08-2010)“…The role of reduced-intensity conditioning allogeneic stem cell transplant (RIC allo-SCT) in aggressive B-cell non-Hodgkin lymphoma (NHL) remains a matter of…”
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