Search Results - "Ayappa, Indu"
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Treatment of Adult Obstructive Sleep Apnea With Positive Airway Pressure: An American Academy of Sleep Medicine Systematic Review, Meta-Analysis, and GRADE Assessment
Published in Journal of clinical sleep medicine (15-02-2019)“…The purpose of this systematic review is to provide supporting evidence for the clinical practice guideline for the treatment of obstructive sleep apnea (OSA)…”
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Treatment of Adult Obstructive Sleep Apnea with Positive Airway Pressure: An American Academy of Sleep Medicine Clinical Practice Guideline
Published in Journal of clinical sleep medicine (15-02-2019)“…This guideline establishes clinical practice recommendations for positive airway pressure (PAP) treatment of obstructive sleep apnea (OSA) in adults and is…”
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Metrics of sleep apnea severity: beyond the apnea-hypopnea index
Published in Sleep (New York, N.Y.) (01-07-2021)“…Abstract Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA has well established cardiovascular and neurocognitive…”
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Obstructive sleep apnea, cognition and Alzheimer's disease: A systematic review integrating three decades of multidisciplinary research
Published in Sleep medicine reviews (01-04-2020)“…Increasing evidence links cognitive-decline and Alzheimer's disease (AD) to various sleep disorders, including obstructive sleep apnea (OSA). With increasing…”
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Scoring accuracy of automated sleep staging from a bipolar electroocular recording compared to manual scoring by multiple raters
Published in Sleep medicine (01-11-2013)“…Abstract Objectives Electroencephalography (EEG) assessment in research and clinical studies is limited by the patient burden of multiple electrodes and the…”
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Obstructive sleep apnea and longitudinal Alzheimer's disease biomarker changes
Published in Sleep (New York, N.Y.) (11-06-2019)“…To determine the effect of self-reported clinical diagnosis of obstructive sleep apnea (OSA) on longitudinal changes in brain amyloid PET and CSF biomarkers…”
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An Official American Thoracic Society Research Statement: Impact of Mild Obstructive Sleep Apnea in Adults
Published in American journal of respiratory and critical care medicine (01-05-2016)“…Mild obstructive sleep apnea (OSA) is a highly prevalent disorder in adults; however, whether mild OSA has significant neurocognitive and cardiovascular…”
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The interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals
Published in Neurobiology of aging (01-06-2014)“…Abstract Previous studies have suggested a link between sleep disordered breathing (SDB) and dementia risk. In the present study, we analyzed the relationship…”
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Obstructive Sleep Apnea, Platelet Aggregation, and Cardiovascular Risk
Published in Journal of the American Heart Association (06-08-2024)“…Although related, the precise mechanisms linking obstructive sleep apnea (OSA) and cardiovascular disease (CVD) are unclear. Platelets are mediators of CVD…”
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Effects of Aging on Slow Wave Sleep Dynamics and Human Spatial Navigational Memory Consolidation
Published in Neurobiology of aging (01-06-2016)“…Abstract The consolidation of spatial navigational memory during sleep is supported by electrophysiological and behavioral evidence. The features of sleep that…”
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Inspiratory flow limitation in a normal population of adults in São Paulo, Brazil
Published in Sleep (New York, N.Y.) (01-11-2013)“…Inspiratory flow limitation (IFL) during sleep occurs when airflow remains constant despite an increase in respiratory effort. This respiratory event has been…”
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Association between lower body temperature and increased tau pathology in cognitively normal older adults
Published in Neurobiology of disease (01-09-2022)“…Preclinical studies suggest body temperature (Tb) and consequently brain temperature has the potential to bidirectionally interact with tau pathology in…”
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Apnea-induced rapid eye movement sleep disruption impairs human spatial navigational memory
Published in The Journal of neuroscience (29-10-2014)“…Hippocampal electrophysiology and behavioral evidence support a role for sleep in spatial navigational memory, but the role of particular sleep stages is less…”
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Selective Continuous Positive Airway Pressure Withdrawal With Supplemental Oxygen During Slow-Wave Sleep as a Method of Dissociating Sleep Fragmentation and Intermittent Hypoxemia-Related Sleep Disruption in Obstructive Sleep Apnea
Published in Frontiers in physiology (22-11-2021)“…Obstructive sleep apnea (OSA) is considered to impair memory processing and increase the expression of amyloid-β (Aβ) and risk for Alzheimer's disease (AD)…”
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The upper airway in sleep: physiology of the pharynx
Published in Sleep Medicine Reviews (01-02-2003)“…The upper airway is the primary conduit for passage of air into the lungs. Its physiology has been the subject of intensive study: both passive mechanical and…”
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Sleep continuity is positively correlated with sleep duration in laboratory nighttime sleep recordings
Published in PloS one (10-04-2017)“…Sleep duration varies widely across individuals and appears to be trait-like. Differences in the stability of underlying sleep processes may underlie this…”
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Interactive Associations of Neuropsychiatry Inventory-Questionnaire Assessed Sleep Disturbance and Vascular Risk on Alzheimer's Disease Stage Progression in Clinically Normal Older Adults
Published in Frontiers in aging neuroscience (10-12-2021)“…To determine whether sleep disturbance (SD) and vascular-risk interact to promote Alzheimer's disease (AD) stage-progression in normal, community-dwelling…”
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Sleep quality, short-term and long-term CPAP adherence
Published in Journal of clinical sleep medicine (15-10-2012)“…Adherence to CPAP therapy is low in patients with obstructive sleep apnea/hypopnea syndrome (OSAHS). The purpose of the present study was to evaluate the…”
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