Cross-sectional study of the clinical characteristics and outcomes of children hospitalized with COVID-19 in Lima, Peru

Coronavirus 2019 (SARS-CoV-2) infection in children occurred in Peru as of March 2020, leading to pediatric patients' hospitalization in areas adapted for this purpose at the Edgardo Rebagliati Martins National Hospital. In the beginning, the demand for hospitalization was low, but it increased...

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Bibliographic Details
Published in:	Medwave Vol. 21; no. 1; p. e8107
Main Authors:	Domínguez Rojas, Jesús, Estupiñan Vigil, Matilde, Garcés-Ghilardi, Raquel, Alvarado-Gamarra, Giancarlo, Del Águila, Olguita, Lope Tenorio, Adanida Flor, Ayón Dejo, Carmen Cecilia, Chonlon Murillo, Kenny, Boluarte Baca, Sebastián, Stapleton Herbozo, Angie, Seminario Aliaga, Ricardo, Reyes Florian, Giuliana, Dávila Riega, Diana, Fernández Suárez, Sarah, Coronado Muñoz, Álvaro
Format:	Journal Article
Language:	English Spanish
Published:	Chile Medwave Estudios Limitada 20-01-2021
Subjects:	Child Child, Preschool coronavirus covid-19 COVID-19 - complications COVID-19 - diagnosis COVID-19 - therapy covid-19 related Cross-Sectional Studies Female Hospitalization Humans Male pediatric multisystem inflammatory disease pediatrics Peru Treatment Outcome Peru COVID-19 coronavirus pediatric multisystem inflammatory disease COVID-19 related pediatrics
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Summary:	Coronavirus 2019 (SARS-CoV-2) infection in children occurred in Peru as of March 2020, leading to pediatric patients' hospitalization in areas adapted for this purpose at the Edgardo Rebagliati Martins National Hospital. In the beginning, the demand for hospitalization was low, but it increased gradually. Consistent with international reports, the majority of patients presented mild or moderate symptoms. Nonetheless, there were also severe cases, even fatal ones. To describe the characteristics and clinical outcome of pediatric patients with COVID-19 hospitalized in a referral hospital in Lima, Peru, between March and August 2020. A descriptive and inferential cross-sectional study was carried out. The population includes all hospitalized patients in the Department of Pediatrics, with clinical and surgical diagnoses associated with COVID-19. We included 100 patients, with an average age of 83.4 ± 54 months, with a predominance of male patients (55%). Hospitalized patients were grouped into five categories: respiratory failure (17%), multisystemic inflammatory syndrome (MIS-C) (31%), neurological presentation (19%), acute abdomen (20%), and patients with oncological problems (13%). Most of the patients (74%) had comorbidities. Regarding the presenting symptoms, intestinal pain predominated in the appendicitis group (90%, p < 0.001), fever was present in most patients with respiratory failure (64.7%); multisystemic inflammatory syndrome (90.3%), neurological manifestations (15.8%), acute abdomen (50%) and oncological conditions (61.5%) were also present in these patients. Kawasaki symptoms were found in 38.7% of the patients with multisystemic inflammatory syndrome. Mortality was 4%. Respiratory problems (29.4%) and multisystemic inflammatory syndrome (22.6%) required admission to intensive care, more frequently than the other presentations (p = 0.008). We conclude that the vulnerability in the pediatric population is the one that has preexisting conditions. We divided our patients according to presentation, diagnosis, and complications, which were predominantly respiratory. We also had oncological patients with COVID-19.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0717-6384 0717-6384
DOI:	10.5867/medwave.2021.01.8107