Search Results - "Ay, Birol"

The long-range interaction between two GNAS imprinting control regions delineates pseudohypoparathyroidism type 1B pathogenesis by Iwasaki, Yorihiro, Aksu, Cagri, Reyes, Monica, Ay, Birol, He, Qing, Bastepe, Murat

“…Genetic defects of GNAS, the imprinted gene encoding the stimulatory G protein α-subunit, are responsible for multiple diseases. Abnormal GNAS imprinting…”
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Maternal GNAS Contributes to the Extra-Large G Protein α-Subunit (XLαs) Expression in a Cell Type-Specific Manner by Cui, Qiuxia, Aksu, Cagri, Ay, Birol, Remillard, Claire E, Plagge, Antonius, Gardezi, Mina, Dunlap, Margaret, Gerstenfeld, Louis C, He, Qing, Bastepe, Murat

“…encodes the stimulatory G protein alpha-subunit (Gsα) and its large variant XLαs. Studies have suggested that XLαs is expressed exclusively paternally. Thus,…”
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Amyloid-β neuropathology induces bone loss in male mice by suppressing bone formation and enhancing bone resorption by Jung, Younghun, Ay, Birol, Cyr, Sajin M., Tognoni, Christina M., Klovdahl, Kaitlin, Matthias, Julia, Cui, Qiuxia, Brooks, Daniel J., Bouxsein, Mary L., Carreras, Isabel, Dedeoglu, Alpaslan, Bastepe, Murat

“…Alzheimer's disease (AD) and osteoporosis often coexist in the elderly. Although observational studies suggest an association between these two diseases, the…”
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1,25-Dihydroxyvitamin D3 regulates furin-mediated FGF23 cleavage by Xie, Han, Bastepe, Isinsu, Zhou, Wen, Ay, Birol, Ceraj, Zara, Portales-Castillo, Ignacio A, Liu, Eva S, Burnett-Bowie, Sherri-Ann M, Jüppner, Harald, Rhee, Eugene P, Bastepe, Murat, Simic, Petra

“…Intact fibroblast growth factor 23 (iFGF23) is a phosphaturic hormone that is cleaved by furin into N-terminal and C-terminal fragments. Several studies have…”
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Hyperglycemia compromises Rat Cortical Bone by Increasing Osteocyte Lacunar Density and Decreasing Vascular Canal Volume by Ay, Birol, Parolia, Kushagra, Liddell, Robert S., Qiu, Yusheng, Grasselli, Giovanni, Cooper, David M. L., Davies, John E.

“…Uncontrolled diabetes is associated with increased risk of bony fractures. However, the mechanisms have yet to be understood. Using high-resolution synchrotron…”
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Vitamin D Receptor Regulates Furin-Mediated FGF23 Cleavage: FR-OR03 by Simic, Petra, Bastepe, Isinsu, Zhou, Wen, Ay, Birol, Rhee, Eugene P., Bastepe, Murat

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Exploring the mechanism behind improved osteointegration of phosphorylated titanium implants with hierarchically structured topography by Jiang, Nan, Guo, Zhijun, Sun, Dan, Ay, Birol, Li, Yubao, Yang, Yutao, Tan, Peijie, Zhang, Li, Zhu, Songsong

“…[Display omitted] •Phosphorylated titanium (TiP-Ti) implants own a hierarchically topography surface.•TiP-Ti modification contributed to a higher bone-implant…”
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Nanoscale implant anchorage aided by cement line deposition into titanium dioxide nanotubes by Grandfield, Kathryn, Binkley, Dakota Marie, Ay, Birol, Liu, Zhen Mei, Wang, Xiaoyue, Davies, John E

“…The success of titanium dental implants relies on osseointegration, the load-bearing connection between bone tissue and the device that, in contact…”
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Bioinspired Fabrication of Calcium-Doped TiP Coating with Nanofibrous Microstructure to Accelerate Osseointegration by Cai, Bianyun, Tan, Peijie, Jiang, Nan, Guo, Zhijun, Ay, Birol, Li, Shujun, Hou, Yi, Li, Yubao, You, Yanjun, Zhang, Li, Zhu, Songsong

“…Bioinspired by the morphology of osteoclast-resorbed bone surfaces, we prepared a calcium-doped titanium phosphate (Ca-TiP) coating, which consists of a…”
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A “best fit” approach for synergistic surface parameters to guide the design of candidate implant surfaces by Ay, Birol, Mendes, Vanessa C., Zhang, Li, Davies, John E.

“…Human bone resorption surfaces can provide a template for endosseous implant surface design. We characterized the topography of such sites using four…”
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Impact of Hyperglycemia on Rat Cortical Bone Microstructure and Osteoprogenitor Cell Exhaustion by Ay, Birol

“…Uncontrolled diabetes has been associated with an increased risk of bone fracture and implant failure. However, the underlying reasons have yet to be entirely…”
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Skeletal muscle patch engineering on synthetic and acellular human skeletal muscle originated scaffolds by Ay, Birol, Karaoz, Erdal, Kesemenli, Cumhur C., Kenar, Halime

“…The reconstruction of skeletal muscle tissue is currently performed by transplanting a muscle tissue graft from local or distant sites of the patient's body,…”
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Gα11 deficiency increases fibroblast growth factor 23 levels in a mouse model of familial hypocalciuric hypercalcemia by Ay, Birol, Cyr, Sajin Marcus, Klovdahl, Kaitlin, Zhou, Wen, Tognoni, Christina M, Iwasaki, Yorihiro, Rhee, Eugene P, Dedeoglu, Alpaslan, Simic, Petra, Bastepe, Murat

“…Fibroblast growth factor 23 (FGF23) production has recently been shown to increase downstream of Gαq/11-PKC signaling in osteocytes. Inactivating mutations in…”
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Reduction of lesion in injured rat spinal cord and partial functional recovery of motility after bone marrow derived mesenchymal stem cell transplantation by Karaoz, Erdal, Kabatas, Serdar, Duruksu, Gokhan, Okcu, Alparslan, Subasi, Cansu, Ay, Birol, Musluman, Murat, Civelek, Erdinc

“…This study aimed to analyze the effect of rat bone marrow-mesenchymal stem cells (rBM-MSCs) delivery on lesion site after spinal cord injury, and to observe…”
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