Search Results - "Axelsen, T. M."

Rationale and study design of a randomized, placebo-controlled, double-blind phase 2b trial to evaluate efficacy, safety, and tolerability of an oral glutaminyl cyclase inhibitor varoglutamstat (PQ912) in study participants with MCI and mild AD—VIVIAD by Vijverberg, E. G. B., Axelsen, T. M., Bihlet, A. R., Henriksen, K., Weber, F., Fuchs, K., Harrison, J. E., Kühn-Wache, K., Alexandersen, P., Prins, N. D., Scheltens, Philip

“…Abstract Background Varoglutamstat (formerly PQ912) is a small molecule that inhibits the activity of the glutaminyl cyclase to reduce the level of…”
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A Genetic Validation of the Neurodegeneration Biomarkers Tau-A and Tau-C - A Mendelian Randomization Study by Axelsen, T. M., Bager, C., Bihlet, A., Karsdal, M. A., Henriksen, K., Tang, M. H. E.

“…Background Disease modifying treatments for dementia are only just surfacing, and their development is still significantly hindered by the lack of validated…”
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Serum Tau-A and Tau-C Levels and Their Association with Cognitive Impairment and Dementia Progression in a Memory Clinic Derived Cohort by Axelsen, Tobias Melton, Høgh, P., Bihlet, A. R., Karsdal, M. A., Henriksen, K., Hasselbalch, S. G., Simonsen, A. H.

“…Background Serum-measured fragments of Tau cleaved by ADAM-10 (Tau-A) and Caspase-3 (Tau-C) have been found linked to change in cognitive function and risk of…”
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Gene Therapy for Parkinson's Disease, An Update by Axelsen, Tobias M, Woldbye, David P D

“…The current mainstay treatment of Parkinson's disease (PD) consists of dopamine replacement therapy which, in addition to causing several side effects, does…”
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Influence of Fermented Milk on Clinical State, Fecal Bacterial Counts and Biochemical Characteristics in Patients with Ileal- Pouch- Anal-Anastomosis by Laake, K. O., Bjørneklett, A., Bakka, A., Midtvedt, T., Norin, K. E., Eide, T. J., Jacobsen, M. B., Lingaas, E., Axelsen, A. K., Løtveit, T., Vatn, M. H.

“…Pouchitis is a condition with acute or chronic inflammation in the ileal pouch of colectomized patients. A disturbed microecology in the pouch has been…”
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