Search Results - "Axelrod, J D"
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Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation
Published in Nature cell biology (01-02-2012)“…Multiciliate cells function prominently in the respiratory system, brain ependyma and female reproductive tract to produce vigorous fluid flow along epithelial…”
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Interaction Between Wingless and Notch Signaling Pathways Mediated by Dishevelled
Published in Science (American Association for the Advancement of Science) (29-03-1996)“…In Drosophila, the Wingless and Notch signaling pathways function in many of the same developmental patterning events. Genetic analysis demonstrates that the…”
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Planar cell polarity signaling: the developing cell's compass
Published in Cold Spring Harbor perspectives in biology (01-09-2009)“…Cells of many tissues acquire cellular asymmetry to execute their physiologic functions. The planar cell polarity system, first characterized in Drosophila, is…”
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Frizzled signaling and the developmental control of cell polarity
Published in Trends in Genetics (01-11-1998)“…Within the last three years, Frizzled receptors have risen from obscurity to celebrity status owing to their functional identification as receptors for the…”
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Book Review Journal Article -
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Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling
Published in Genes & development (15-05-2001)“…Drosophila epithelia acquire a planar cell polarity (PCP) orthogonal to their apical-basal axes. Frizzled (Fz) is the receptor for the PCP signal, and…”
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wingless refines its own expression domain on the Drosophila wing margin. [Erratum: Dec 12, 1996, v. 384 (6609), p. 597.]
Published in Nature (London) (07-11-1996)“…The imaginal discs of Drosophila, which give rise to the adult appendages, are patterned during a period of intense cell proliferation. The specification of…”
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Drosophila Rho-Associated Kinase (Drok) Links Frizzled-Mediated Planar Cell Polarity Signaling to the Actin Cytoskeleton
Published in Cell (06-04-2001)“…Frizzled (Fz) and Dishevelled (Dsh) are components of an evolutionarily conserved signaling pathway that regulates planar cell polarity. How this signaling…”
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Fidelity in planar cell polarity signalling
Published in Nature (London) (30-01-2003)“…The polarity of Drosophila wing hairs displays remarkable fidelity. Each of the approximately 30,000 wing epithelial cells constructs an actin-rich prehair…”
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Prickle Mediates Feedback Amplification to Generate Asymmetric Planar Cell Polarity Signaling
Published in Cell (03-05-2002)“…Planar cell polarity signaling in Drosophila requires the receptor Frizzled and the cytoplasmic proteins Dishevelled and Prickle. From initial, symmetric…”
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Regulation of Frizzled by Fat-like Cadherins during Planar Polarity Signaling in the Drosophila Compound Eye
Published in Cell (08-03-2002)“…Planar polarity is evident in the coordinated orientation of ommatidia in the Drosophila eye. This process requires that the R3 photoreceptor precursor of each…”
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Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
Published in Genes & development (15-08-1998)“…In Drosophila, planar cell polarity (PCP) signaling is mediated by the receptor Frizzled (Fz) and transduced by Dishevelled (Dsh). Wingless (Wg) signaling also…”
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Proline-independent binding of PUT3 transcriptional activator protein detected by footprinting in vivo
Published in Molecular and Cellular Biology (01-01-1991)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Naked cuticle targets dishevelled to antagonize Wnt signal transduction
Published in Genes & development (15-03-2001)“…In Drosophila embryos the protein Naked cuticle (Nkd) limits the effects of the Wnt signal Wingless (Wg) during early segmentation. nkd loss of function…”
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wingless signaling pathway is directly involved in Drosophila heart development
Published in Developmental biology (10-07-1996)“…Heart development in both vertebrates and Drosophila is initiated by bilaterally symmetrical primordia that may be of equivalent embryological origin: the…”
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The collection and evaluation of peripheral blood progenitor cells sufficient for repetitive cycles of high-dose chemotherapy support
Published in Transfusion (Philadelphia, Pa.) (01-10-1995)“…The development of an optimized peripheral blood progenitor cell (PBPC) harvest protocol to provide support for repetitive chemotherapy cycles is described…”
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Regulation of PCP by the Fat signaling pathway
Published in Genes & development (15-10-2013)“…Planar cell polarity (PCP) in epithelia, orthogonal to the apical-basal axis, is essential for numerous developmental events and physiological functions…”
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GAL4 disrupts a repressing nucleosome during activation of GAL1 transcription in vivo
Published in Genes & development (01-05-1993)“…Photofootprinting in vivo of GAL1 reveals an activation-dependent pattern between the UASG and the TATA box, in a sequence not required for transcriptional…”
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Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2
Published in Mechanisms of development (01-08-1996)“…The segment polarity gene dishevelled (dsh) of Drosophila is required for pattern formation of the embryonic segments and the adult imaginal discs.dsh encodes…”
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Unimpaired signal transduction by the adipocyte insulin receptor following its partial proteolytic fragmentation
Published in The Journal of biological chemistry (25-02-1981)Get full text
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Using methadone to treat opioid-induced hyperalgesia and refractory pain
Published in Journal of opioid management (01-03-2007)“…A patient was treated for several years with high doses of opioids for malignant pain. During a recent hospitalization, the patient's pain remained…”
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