Search Results - "Axelrad, Daniel A"
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The Navigation Guide - evidence-based medicine meets environmental health: systematic review of human evidence for PFOA effects on fetal growth
Published in Environmental health perspectives (01-10-2014)“…The Navigation Guide methodology was developed to meet the need for a robust method of systematic and transparent research synthesis in environmental health…”
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The relationship between childhood blood lead levels below 5 µg/dL and childhood intelligence quotient (IQ): Protocol for a systematic review and meta-analysis
Published in Environment international (01-11-2022)“…•Childhood blood lead (Pb) is known to reduce intelligence quotient (IQ).•The quantitative relationship of blood Pb to IQ is important to inform policy.•This…”
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The Navigation Guide - evidence-based medicine meets environmental health: systematic review of nonhuman evidence for PFOA effects on fetal growth
Published in Environmental health perspectives (01-10-2014)“…In contrast to current methods of expert-based narrative review, the Navigation Guide is a systematic and transparent method for synthesizing environmental…”
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Current practice and recommendations for advancing how human variability and susceptibility are considered in chemical risk assessment
Published in Environmental health (12-01-2023)“…A key element of risk assessment is accounting for the full range of variability in response to environmental exposures. Default dose-response methods…”
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Addressing systemic problems with exposure assessments to protect the public's health
Published in Environmental health (12-01-2023)“…Understanding, characterizing, and quantifying human exposures to environmental chemicals is critical to protect public health. Exposure assessments are key to…”
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Dose-Response Relationship of Prenatal Mercury Exposure and IQ: An Integrative Analysis of Epidemiologic Data
Published in Environmental health perspectives (01-04-2007)“…Background: Prenatal exposure to mercury has been associated with adverse childhood neurologic outcomes in epidemiologic studies. Dose-response information for…”
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Blood Lead and Other Metal Biomarkers as Risk Factors for Cardiovascular Disease Mortality
Published in Medicine (Baltimore) (01-01-2016)“…Analyses of the Third National Health and Nutrition Examination Survey (NHANES III) in 1988 to 1994 found an association of increasing blood lead levels < 10…”
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Estimated Daily Phthalate Exposures in a Population of Mothers of Male Infants Exhibiting Reduced Anogenital Distance
Published in Environmental health perspectives (01-06-2006)“…Phthalate diesters have been shown to be developmental and reproductive toxicants in animal studies. A recent epidemiologic study showed certain phthalates to…”
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Application of probabilistic methods to address variability and uncertainty in estimating risks for non-cancer health effects
Published in Environmental health (12-01-2023)“…Human health risk assessment currently uses the reference dose or reference concentration (RfD, RfC) approach to describe the level of exposure to chemical…”
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Advancing the science on chemical classes
Published in Environmental health (12-01-2023)“…Hazard identification, risk assessment, regulatory, and policy activity are usually conducted on a chemical-by-chemical basis. Grouping chemicals into…”
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PCB body burdens in US women of childbearing age 2001–2002: An evaluation of alternate summary metrics of NHANES data
Published in Environmental research (01-05-2009)“…An extensive body of epidemiologic data associates prenatal exposure to polychlorinated biphenyls (PCBs) with neurodevelopmental deficits and other childhood…”
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Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis
Published in Environmental health perspectives (01-08-2017)“…In the United States, one in six children are affected by neurodevelopmental disorders, and polybrominated diphenyl ethers (PBDEs) in flame-retardant chemicals…”
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Evaluating Cumulative Organophosphorus Pesticide Body Burden of Children: A National Case Study
Published in Environmental science & technology (15-10-2009)“…Biomonitoring is a valuable tool for identifying exposures to chemicals that pose potential harm to human health. However, to date there has been little…”
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The Navigation Guide - evidence-based medicine meets environmental health: integration of animal and human evidence for PFOA effects on fetal growth
Published in Environmental health perspectives (01-10-2014)“…The Navigation Guide is a novel systematic review method to synthesize scientific evidence and reach strength of evidence conclusions for environmental health…”
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Beyond the RfD: Broad Application of a Probabilistic Approach to Improve Chemical Dose-Response Assessments for Noncancer Effects
Published in Environmental health perspectives (01-06-2018)“…The National Academies recommended risk assessments redefine the traditional noncancer Reference Dose (RfD) as a probabilistically derived risk-specific dose,…”
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Toxic Substances Control Act (TSCA) Implementation: How the Amended Law Has Failed to Protect Vulnerable Populations from Toxic Chemicals in the United States
Published in Environmental science & technology (06-09-2022)“…Exposures to industrial chemicals are widespread and can increase the risk of adverse health effects such as cancer, developmental disorders, respiratory…”
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Estimating the health benefits of environmental regulations
Published in Science (American Association for the Advancement of Science) (04-08-2017)“…Changes needed for complete benefits assessment Assessing health benefits of policies addressing environmental contaminants is important for decision-making…”
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Preterm birth and economic benefits of reduced maternal exposure to fine particulate matter
Published in Environmental research (01-03-2019)“…Preterm birth (PTB) is a predictor of infant mortality and later-life morbidity. Despite recent declines, PTB rates remain high in the United States. Growing…”
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Dietary Exposures to Food Contaminants across the United States
Published in Environmental research (01-10-2000)“…Food consumption is an important route of human exposure to pesticides and industrial pollutants. Average dietary exposures to 37 pollutants were calculated…”
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