Search Results - "Awatramani, Rajeshwar B"
-
1
Defining Midbrain Dopaminergic Neuron Diversity by Single-Cell Gene Expression Profiling
Published in Cell reports (Cambridge) (06-11-2014)“…Effective approaches to neuropsychiatric disorders require detailed understanding of the cellular composition and circuitry of the complex mammalian brain…”
Get full text
Journal Article -
2
Assembly of the Brainstem Cochlear Nuclear Complex Is Revealed by Intersectional and Subtractive Genetic Fate Maps
Published in Neuron (Cambridge, Mass.) (20-04-2006)“…The cochlear nuclear complex (CN) is the entry point for central auditory processing. Although constituent neurons have been studied physiologically, their…”
Get full text
Journal Article -
3
The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age
Published in PLoS biology (01-12-2007)“…Parkinson disease affects more than 1% of the population over 60 y old. The dominant models for Parkinson disease are based on the use of chemical toxins to…”
Get full text
Journal Article -
4
Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis
Published in Nature neuroscience (01-02-2009)“…The floor plate is not usually a neurogenic structure, but in the embryonic midbrain, dopaminergic neurons do develop from floor plate. This study shows that…”
Get full text
Journal Article -
5
Dysregulation of Local Stem/Progenitor Cells as a Common Cellular Mechanism for Heterotopic Ossification
Published in Stem cells (Dayton, Ohio) (01-01-2009)“…Heterotopic ossification (HO), the abnormal formation of true marrow‐containing bone within extraskeletal soft tissues, is a serious bony disorder that may be…”
Get full text
Journal Article -
6
Hindbrain Rhombic Lip Is Comprised of Discrete Progenitor Cell Populations Allocated by Pax6
Published in Neuron (Cambridge, Mass.) (22-12-2005)“…The lower rhombic lip (LRL) is a germinal zone in the dorsal hindbrain productive of tangentially migrating neurons, streaming extramurally (mossy fiber…”
Get full text
Journal Article -
7
Ligand-activated Flpe for temporally regulated gene modifications
Published in Genesis (New York, N.Y. : 2000) (01-03-2005)“…The selectivity by which site‐specific recombinase‐mediated genetic changes can be targeted to specific cells in the mouse has been limited by the fact that…”
Get full text
Journal Article -
8
Redefining the serotonergic system by genetic lineage
Published in Nature neuroscience (01-04-2008)“…Central serotonin-producing neurons are heterogeneous-differing in location, morphology, neurotoxin sensitivity and associated clinical disorders-but the…”
Get full text
Journal Article -
9
The floor plate gene, foxa2, is required for the generation and maintenance of midbrain dopamine neurons
Published in Developmental biology (15-07-2008)Get full text
Journal Article -
10
Defining midbrain dopaminergic neuron diversity by single-cell gene profiling
Published in Cell reports (Cambridge) (30-10-2014)“…Effective approaches to neuropsychiatric disorders require detailed understanding of the cellular composition and circuitry of the complex mammalian brain…”
Get full text
Journal Article -
11
Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis
Published in Developmental biology (15-07-2009)Get full text
Journal Article -
12
Redefining the central serotonergic system based on genetic lineage
Published in Nature neuroscience (16-03-2008)“…Central serotonin (5-HT, 5-hydroxytryptamine)-producing neurons are heterogeneous, differing in location, morphology, neurotoxin sensitivity and associated…”
Get full text
Journal Article