Search Results - "Awasthi, Yogesh"

Press “A” for Artificial Intelligence in Agriculture: A Review by Yogesh Awasthi

“…Agriculture is the backbone of the developing country. In old era agriculture was based on the experience which was shared by people to people but in this…”
Get full text

Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity by Awasthi, Yogesh C., Ramana, Kota V., Chaudhary, Pankaj, Srivastava, Satish K., Awasthi, Sanjay

“…Glutathione-S-Transferases (GSTs) have primarily been thought to be xenobiotic metabolizing enzymes that protect cells from toxic drugs and environmental…”
Get full text

4-Hydroxynonenal Induces G2/M Phase Cell Cycle Arrest by Activation of the Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR)/Checkpoint Kinase 1 (Chk1) Signaling Pathway by Chaudhary, Pankaj, Sharma, Rajendra, Sahu, Mukesh, Vishwanatha, Jamboor K., Awasthi, Sanjay, Awasthi, Yogesh C.

“…4-Hydroxynonenal (HNE) has been widely implicated in the mechanisms of oxidant-induced toxicity, but the detrimental effects of HNE associated with DNA damage…”
Get full text

Rlip depletion prevents spontaneous neoplasia in TP53 null mice by Awasthi, Sanjay, Tompkins, Joshua, Singhal, Jyotsana, Riggs, Arthur D., Yadav, Sushma, Wu, Xiwei, Singh, Sharda, Warden, Charles, Liu, Zheng, Wang, Jinhui, Slavin, Thomas P., Weitzel, Jeffrey N., Yuan, Yate-Ching, Awasthi, Meenakshi, Srivastava, Satish K., Awasthi, Yogesh C., Singhal, Sharad S.

“…TP53 (p53) is a tumor suppressor whose functions are lost or altered in most malignancies. p53 homozygous knockout (p53−/−) mice uniformly die of spontaneous…”
Get full text

Role of SMC1 in overcoming drug resistance in triple negative breast cancer by Yadav, Sushma, Sehrawat, Archana, Eroglu, Zeynep, Somlo, George, Hickey, Robert, Yadav, Sailee, Liu, Xueli, Awasthi, Yogesh C, Awasthi, Sanjay

“…Triple-negative breast cancer (TNBC) is one of the hardest subtypes of breast cancer to treat due to the heterogeneity of the disease and absence of…”
Get full text

Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling by Chaudhary, Pankaj, Sharma, Rajendra, Sharma, Abha, Vatsyayan, Rit, Yadav, Sushma, Singhal, Sharad S, Rauniyar, Navin, Prokai, Laszlo, Awasthi, Sanjay, Awasthi, Yogesh C

“…In recent years, 4-hydroxy-2-nonenal (4-HNE) has emerged as an important second messenger in cell cycle signaling. Here, we demonstrate that 4-HNE induces…”
Get full text

P300 regulates the human RLIP76 promoter activity and gene expression by Sehrawat, Archana, Yadav, Sushma, Awasthi, Yogesh C., Basu, Alakananda, Warden, Charles, Awasthi, Sanjay

“…A 76-kDa Ral-interacting protein (RLIP76) has been implicated in the pathogenesis of cancer and diabetes. It is often over expressed in human malignant cell…”
Get full text

Contrasting of Various Algorithmic Techniques to Solve Knapsack 0-1 Problem by Awasthi, Yogesh, Sharma, Ashish

“…This paper will point of convergence on a relative assessment and estimation of the dynamic programming, B&B, Greedy and Genetic algorithm including of the…”
Get full text

Enhancing Approach for Information Security in Hadoop by Awasthi, Yogesh, Sharma, Ashish

“…Using the Hadoop package, a proposed secure cloud computing system was designed. Hadoop would use the area to establish and enhance the security for saving and…”
Get full text

Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis by Sharma, Rajendra, Yang, Yusong, Sharma, Abha, Awasthi, Sanjay, Awasthi, Yogesh C

“…It has been known that glutathione S-transferases (GSTs) can reduce lipid hydroperoxides through their Se-independent glutathione peroxidase activity and that…”
Get more information

RLIP76: A Target for Kidney Cancer Therapy by SINGHAL, Sharad S, SINGHAL, Jyotsana, YADAV, Sushma, SAHU, Mukesh, AWASTHI, Yogesh C, AWASTHI, Sanjay

“…RLIP76 is a multifunctional transporter protein that serves as an energy-dependent efflux mechanism for endogenously generated toxic metabolites as well as…”
Get full text

4-Hydroxynonenal Self-Limits Fas-Mediated DISC-Independent Apoptosis by Promoting Export of Daxx from the Nucleus to the Cytosol and Its Binding to Fas by Sharma, Rajendra, Sharma, Abha, Dwivedi, Seema, Zimniak, Piotr, Awasthi, Sanjay, Awasthi, Yogesh C

“…Previously, we have shown that 4-hydroxynonenal (4-HNE) induces Fas-mediated apoptosis in HLE B-3 cells through a pathway which is independent of FasL, FADD,…”
Get full text

Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death by Awasthi, Yogesh C., Sharma, Rajendra, Sharma, Abha, Yadav, Sushma, Singhal, Sharad S., Chaudhary, Pankaj, Awasthi, Sanjay

“…Within the last two decades, 4-hydroxynonenal has emerged as an important second messenger involved in the regulation of various cellular processes. Our recent…”
Get full text

The expression and function of vascular endothelial growth factor in retinal pigment epithelial (RPE) cells is regulated by 4-hydroxynonenal (HNE) and glutathione S-transferaseA4-4 by Vatsyayan, Rit, Lelsani, Poorna Chandra Rao, Chaudhary, Pankaj, Kumar, Sushil, Awasthi, Sanjay, Awasthi, Yogesh C.

“…► Low concentration of HNE (0.1–1.0μM) induced secretion of VEGF in RPE cells. ► VEGF secreted medium of RPE cells promoted proliferation of endothelial cells…”
Get full text

Role of the Electrophilic Lipid Peroxidation Product 4-Hydroxynonenal in the Development and Maintenance of Obesity in Mice by Singh, Sharda P, Niemczyk, Maciej, Saini, Deepti, Awasthi, Yogesh C, Zimniak, Ludwika, Zimniak, Piotr

“…The lipid peroxidation product 4-hydroxynonenal (4-HNE) is a signaling mediator with wide-ranging biological effects. In this paper, we report that disruption…”
Get full text

The Framingham Study on Cardiovascular Disease Risk and Stress-Defenses: A Historical Review by Abohelwa, Mostafa, Kopel, Jonathan, Shurmur, Scott, Ansari, Mohammad M., Awasthi, Yogesh, Awasthi, Sanjay

“…The Framingham Heart Study (FHS) began in 1949 with the goal of defining the epidemiology of hypertensive or arteriosclerotic heart disease in the population…”
Get full text

Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth by Ramana, Kota V, Bhatnagar, Aruni, Srivastava, Sanjay, Yadav, Umesh C, Awasthi, Sanjay, Awasthi, Yogesh C, Srivastava, Satish K

“…Products of lipid peroxidation such as 4-hydroxy-trans-2-nonenal (HNE) trigger multiple signaling cascades that variably affect cell growth, differentiation,…”
Get full text

Anticancer activity of 2'-hydroxyflavanone towards lung cancer by Awasthi, Sanjay, Singhal, Sharad S, Singhal, Jyotsana, Nagaprashantha, Lokesh, Li, Hongzhi, Yuan, Yate-Ching, Liu, Zheng, Berz, David, Igid, Henry, Green, William C, Tijani, Lukman, Tonk, Vijay, Rajan, Aditya, Awasthi, Yogesh, Singh, Sharda P

“…In previous studies, we found that 2'-hydroxyflavonone (2HF), a citrus flavonoid, inhibits the growth of renal cell carcinoma in a VHL-dependent manner. This…”
Get full text

4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells by Sharma, Abha, Sharma, Rajendra, Chaudhary, Pankaj, Vatsyayan, Rit, Pearce, Virginia, Jeyabal, Prince V.S., Zimniak, Piotr, Awasthi, Sanjay, Awasthi, Yogesh C.

“…4-Hydroxynonenal (4-HNE) has been suggested to be involved in stress-induced signaling for apoptosis. In present studies, we have examined the effects of 4-HNE…”
Get full text

Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-Binding Protein 1) by SINGHAL, Sharad S, SINGHAL, Jyotsana, YADAV, Sushma, DWIVEDI, Seema, BOOR, Paul J, AWASTHI, Yogesh C, AWASTHI, Sanjay

“…Ral-binding protein 1 (RALBP1) is a stress-responsive and stress-protective multispecific transporter of glutathione conjugates (GS-E) and xenobiotic toxins…”
Get full text