Search Results - "Awasthi, Anshumali"

Oral Bioavailability Enhancement of Exemestane from Self-Microemulsifying Drug Delivery System (SMEDDS) by Singh, Ajeet K., Chaurasiya, Akash, Awasthi, Anshumali, Mishra, Gautam, Asati, Dinesh, Khar, Roop K., Mukherjee, Rama

“…Limited aqueous solubility of exemestane leads to high variability in absorption after oral administration. To improve the solubility and bioavailability of…”
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Development and validation of reversed phase liquid chromatographic method utilizing ultraviolet detection for quantification of irinotecan (CPT-11) and its active metabolite, SN-38, in rat plasma and bile samples: Application to pharmacokinetic studies by Bansal, Tripta, Awasthi, Anshumali, Jaggi, Manu, Khar, Roop K., Talegaonkar, Sushama

“…A new, simple, sensitive and specific reversed-phase high performance liquid chromatographic (HPLC) method using ultraviolet detection was developed and…”
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Evaluation of herb-drug interaction of a polyherbal Ayurvedic formulation through high throughput cytochrome P450 enzyme inhibition assay by Pandit, Subrata, Kanjilal, Satyajyoti, Awasthi, Anshumali, Chaudhary, Anika, Banerjee, Dipankar, Bhatt, B.N., Narwaria, Avinash, Singh, Rahul, Dutta, Kakoli, Jaggi, Manu, Singh, Anu T., Sharma, Neena, Katiyar, Chandra Kant

“…Arishtas are Ayurvedic formulation made with decoction of herbs. Arjunarishta formulation is being used in Ayurveda for cardio-protective activity…”
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Antidiabetic potential of polyherbal formulation DB14201: Preclinical development, safety and efficacy studies by Gopalakrishna Pillai, Geetha Krishnan, Bharate, Sonali S., Awasthi, Anshumali, Verma, Ritu, Mishra, Gautam, Singh, Anu T., Jaggi, Manu, Mithal, Ambrish, Vishwakarma, Ram A.

“…The poly-herbal formulation DB14201 is a new combination of ayurvedic ingredients for treatment of diabetes. The aim of present study was to investigate safety…”
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Pre-clinical evidence for altered absorption and biliary excretion of irinotecan (CPT-11) in combination with quercetin: Possible contribution of P-glycoprotein by Bansal, Tripta, Awasthi, Anshumali, Jaggi, Manu, Khar, Roop K., Talegaonkar, Sushama

“…P-glycoprotein (P-gp) is found to play a very significant role in intestinal and biliary transport of irinotecan and its active metabolite, SN-38. This makes…”
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Preclinical pharmacokinetics and bioavailability of noscapine, a tubulin-binding anticancer agent by ANEJA, Ritu, DHIMAN, Neerupma, IDNANI, Jyoti, AWASTHI, Anshumali, ARORA, Sudershan K, CHANDRA, Ramesh, JOSHI, Harish C

“…Noscapine, a naturally occurring antitussive phthalideisoquinoline alkaloid, is a tubulin-binding agent currently in Phase I/II clinical trials for anticancer…”
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Pharmacokinetic evaluation of C-3 modified 1,8-naphthyridine-3-carboxamide derivatives with potent anticancer activity: lead finding by Awasthi, Anshumali, Lohani, Mohtashim, Singh, Manoj K, Singh, Anu T, Jaggi, Manu

“…To develop naphthyridine derivatives as anticancer candidates, pharmacokinetic (PK) evaluations of 10 novel derivatives of…”
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Cellular mechanisms mediating the anticancer activity of a novel polyherbal formulation by Shraibom, Nadav Menahem, Jaggi, Manu, Singh, Anu T, Verma, Ritu, Madaan, Alka, Singh, Pratibha, Awasthi, Anshumali, Joshi, Vidushi, Kishore, Amitesh, Dobhal, Sheetal, Kar, Ronodip, Meena, Kalpana

“…Abstract only…”
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Efficiency and mechanism of intracellular paclitaxel delivery by novel nanopolymer-based tumor-targeted delivery system, Nanoxel(TM) by Madaan, Alka, Singh, Pratibha, Awasthi, Anshumali, Verma, Ritu, Singh, Anu T, Jaggi, Manu, Mishra, Shiva Kant, Kulkarni, Sadanand, Kulkarni, Hrishikesh

“…An increasing research interest has been directed toward nanoparticle-based drug delivery systems for their advantages. The appropriate amalgamation of pH…”
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High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats by Singh, Ajeet Kumar, Chaurasiya, Akash, Jain, Gaurav K., Awasthi, Anshumali, Asati, Dinesh, Mishra, Gautam, Khar, Roop K., Mukherjee, Rama

“…Bicalutamide is a non-steroidal antiandrogen and is an oral medication that is used for treating prostate cancer. To evaluate the bioavailability of…”
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Non‐toxic melanoma therapy by a novel tubulin‐binding agent by Aneja, Ritu, Asress, Seneshaw, Dhiman, Neerupma, Awasthi, Anshumali, Rida, Padmashree C.G., Arora, Sudarshan K., Zhou, Jun, Glass, Jonathan D., Joshi, Harish C.

“…(S)‐3‐((R)‐9‐bromo‐4‐methoxy‐6‐methyl‐5,6,7,8‐tetrahydro‐[1,3]dioxolo[4,5‐g]isoquino‐lin‐5‐yl)‐6,7‐dimethoxyisobenzofuran‐1(3H)‐one (EM011) is a…”
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Application of a liquid chromatography-electrospray mass spectrometry (LC/MS) method to the biodistribution and excretion studies of novel 5′-chloro-2, 3-didehydroindolo (2′, 3′: 2, 3) betulinic acid (DRF-4012) in tumour-bearing mice by Mishra, Gautam, Singh, Manoj Kumar, Awasthi, Anshumali, Singh, Anu T., Jaggi, Manu, Ahmad, Farhan J.

“…Novel betulinic acid derivative 5′-chloro-2, 3-didehydroindolo [2′, 3′: 2, 3] betulinic acid (DRF-4012) is a new effective lupane type triterpenes with greater…”
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Efficiency and mechanism of intracellular paclitaxel delivery by novel nanopolymer-based tumor-targeted delivery system, NanoxelTM by Madaan, Alka, Singh, Pratibha, Awasthi, Anshumali, Verma, Ritu, Singh, Anu T., Jaggi, Manu, Mishra, Shiva Kant, Kulkarni, Sadanand, Kulkarni, Hrishikesh

“…Introduction An increasing research interest has been directed toward nanoparticle-based drug delivery systems for their advantages. The appropriate…”
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LC-UV Detection of 5′-Chloro-2,3-didehydroindolo[2′,3′:2,3]betulinic Acid in Rat Plasma and Its Application to a Pharmacokinetic Study by Mishra, Gautam, Singh, Manoj Kumar, Awasthi, Anshumali, Jaggi, Manu, Ahmad, Farhan J

“…A simple, rapid and sensitive high-performance liquid chromatography LC (HPLC) method of determining the concentration of the novel betulinic acid derivative…”
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Evaluation of in vitro Anti-psoriatic Activity of a Novel Polyherbal Formulation by Multiparametric Analysis by Shraibom, Nadav, Madaan, Alka, Joshi, Vidushi, Verma, Ritu, Chaudhary, Anika, Mishra, Gautam, Awasthi, Anshumali, Singh, Anu Taneja, Jaggi, Manu

“…We have developed a novel aqueous polyherbal formulation (SIRB-001) consisting of 3 herbs; Rheum palmatum L., Lonicera Japonica and Rehmannia glutinosa Libosch…”
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