Search Results - "Awan, Ahmed Zuhier"
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Assessment of Knowledge of Monkeypox Viral Infection among the General Population in Saudi Arabia
Published in Pathogens (Basel) (01-08-2022)“…Monkeypox is re-emerging and spreading over the world, posing a serious threat to human life, especially in non-endemic countries, including Saudi Arabia. Due…”
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Molecular insights into the coding region mutations of low‐density lipoprotein receptor adaptor protein 1 (LDLRAP1) linked to familial hypercholesterolemia
Published in The journal of gene medicine (01-06-2020)“…Background Familial hypercholesterolemia (FH) is a lipid disorder caused by pathogenic mutations in LDLRAP1 gene. The present study has aimed to deepen our…”
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A Comparison between Eight Formulas for the Estimation of Plasma Low-Density Lipoprotein Cholesterol in the Saudi Arabian Population
Published in Journal of Applied Hematology (01-10-2022)“…CONTEXT: Low-density lipoprotein cholesterol (LDL-C) is the classical target in cardiovascular (CV) disease management and is usually estimated by Friedewald's…”
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Etodolac Fortified Sodium Deoxycholate Stabilized Zein Nanoplatforms for Augmented Repositioning Profile in Human Hepatocellular Carcinoma: Assessment of Bioaccessibility, Anti-Proliferation, Pro-Apoptosis and Oxidant Potentials in HepG2 Cells
Published in Pharmaceuticals (Basel, Switzerland) (24-07-2022)“…This work aimed to enhance the purposing profile of Etodolac (ETD) in Human Hepatocellular Carcinoma (HCC) HepG2 cells using sodium deoxycholate stabilized…”
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Saudi Familial Hypercholesterolemia Patients With Rare LDLR Stop Gain Variant Showed Variable Clinical Phenotype and Resistance to Multiple Drug Regimen
Published in Frontiers in medicine (25-06-2021)“…Familial hypercholesterolemia (FH), a well-known lipid disease caused by inherited genetic defects in cholesterol uptake and metabolism is underdiagnosed in…”
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Structural characterization and conformational dynamics of alpha-1 antitrypsin pathogenic variants causing alpha-1-antitrypsin deficiency
Published in Frontiers in molecular biosciences (24-11-2022)“…Alpha-1 antitrypsin deficiency (A1ATD) is a progressive lung disease caused by inherited pathogenic variants in the gene. However, their actual role in…”
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Low resolution protein mapping and KB-R7943 drug-protein molecular interaction analysis of long-QT syndrome linked KCNH2 mutations
Published in All life (Online) (01-01-2020)Get full text
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Multilevel systems biology analysis of lung transcriptomics data identifies key miRNAs and potential miRNA target genes for SARS-CoV-2 infection
Published in Computers in biology and medicine (01-08-2021)“…The spread of a novel severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) has affected both the public health and the global economy. The current…”
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Spectral signal processing approaches for selective quantification of the recently FDA approved brand-new combination of Vaborbactam and Meropenem; for conformity assessment of bulk and batch release
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-04-2020)“…Vaborbactam (VBR) and Meropenem (MRP) is a recently approved combination for treatment of complicated urinary tract infection (cUTI). Three different signal…”
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Structural and Molecular Interaction Studies on Familial Hypercholesterolemia Causative PCSK9 Functional Domain Mutations Reveals Binding Affinity Alterations with LDLR
Published in International journal of peptide research and therapeutics (01-03-2021)“…Familial hypercholesterolemia (FH) is a metabolic disease caused by the inherited pathogenic mutations in PCSK9 gene. This study has evaluated the potential of…”
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Interpreting the Mechanism of APOE (p.Leu167del) Mutation in the Incidence of Familial Hypercholesterolemia; An In-silico Approach
Published in The open cardiovascular medicine journal (01-01-2017)“…Apolipoprotein E (APOE) gene is a ligand protein in humans which mediates the metabolism of cholesterol by binding to the low-density lipoprotein receptor…”
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