Search Results - "Awadh, Ahmed Abdullah Al"
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Biomedical applications of selective metal complexes of indole, benzimidazole, benzothiazole and benzoxazole: A review (From 2015 to 2022)
Published in Saudi pharmaceutical journal (01-09-2023)“…Indole, benzoxazole benzothiazole and benzimidazole are excellent classes of organic heterocyclic compounds. These compounds show significant application in…”
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Pectin: A Bioactive Food Polysaccharide with Cancer Preventive Potential
Published in Molecules (Basel, Switzerland) (31-10-2022)“…Pectin is an acidic heteropolysaccharide found in the cell walls and the primary and middle lamella of land plants. To be authorized as a food additive,…”
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Influence of the Extraction Method on the Quality and Chemical Composition of Walnut ( Juglans regia L.) Oil
Published in Molecules (Basel, Switzerland) (01-11-2022)“…The present study investigated and compared the quality and chemical composition of Moroccan walnut (Juglans regia L.) oil. This study used three extraction…”
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4
Natural Small Molecules in Gastrointestinal Tract and Associated Cancers: Molecular Insights and Targeted Therapies
Published in Molecules (Basel, Switzerland) (01-09-2022)“…Gastric cancer is one of the most common cancers of the gastrointestinal tract. Although surgery is the primary treatment, serious maladies that dissipate to…”
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Determination of Chemical Compounds and Investigation of Biological Properties of Matricaria chamomilla Essential Oils, Honey, and Their Mixture
Published in Molecules (Basel, Switzerland) (09-09-2022)“…This exploratory investigation aimed to determine the chemical composition and evaluate some biological properties, such as antioxidant, anti-inflammatory,…”
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Determination of Chemical Composition and Investigation of Biological Activities of Ocimum basilicum L
Published in Molecules (Basel, Switzerland) (06-01-2023)“…This study aimed to determine the chemical composition of the essential oils (EOs) of L., as well as to evaluate the antibacterial, antidiabetic,…”
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Integrated Machine Learning and Chemoinformatics-Based Screening of Mycotic Compounds against Kinesin Spindle ProteinEg5 for Lung Cancer Therapy
Published in Molecules (Basel, Switzerland) (02-03-2022)“…Among the various types of cancer, lung cancer is the second most-diagnosed cancer worldwide. The kinesin spindle protein, Eg5, is a vital protein behind…”
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Acute and Subacute Toxicity Studies of Erodium guttatum Extracts by Oral Administration in Rodents
Published in Toxins (27-10-2022)“…The present study aimed to evaluate the acute and subacute toxicity profiles of extracts in mice using the methods described in the guidelines of the OECD. In…”
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9
Hepatitis B among University Population: Prevalence, Associated Risk Factors, Knowledge Assessment, and Treatment Management
Published in Viruses (31-08-2022)“…Background: Very few studies have been reported on hepatitis B in the State of Azad Jammu and Kashmir, Pakistan, and none of them are specific to the…”
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Design, synthesis and preclinical evaluations of (s)-2-((s)-1-benzyl-2,5-dioxopyrrolidin-3-yl)-3-(4-isopropylphenyl)-2-methylpropanal (succ-5) as cardioprotective, hepatoprotective and lipid lowering molecule. in-vivo and in-silico approaches
Published in Arabian journal of chemistry (01-02-2023)“…In this study, the newly synthesized compound (Succ-5) was analyzed through spectral methods, seen for potential receptor targets via molecular docking, and…”
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Chemical Composition, Antioxidant, Anti-Diabetic, Anti-Acetylcholinesterase, Anti-Inflammatory, and Antimicrobial Properties of Arbutus unedo L. and Laurus nobilis L. Essential Oils
Published in Life (Basel, Switzerland) (14-11-2022)“…The objectives of this work were to determine the phytochemical composition and antioxidant, anti-diabetic, antibacterial, anti-inflammatory, and…”
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Nutritional, Antioxidant, Antimicrobial, and Anticholinesterase Properties of Phyllanthus emblica: A Study Supported by Spectroscopic and Computational Investigations
Published in Metabolites (14-09-2023)“…Dietary fruits and vegetables play a vital role as food and drugs and are the main sources of antioxidant defences against degenerative diseases, such as brain…”
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13
New Megastigmane and Polyphenolic Components of Henna Leaves and Their Tumor-Specific Cytotoxicity on Human Oral Squamous Carcinoma Cell Lines
Published in Antioxidants (01-11-2023)“…Polyphenols have a variety of phenolic hydroxyl and carbonyl functionalities that enable them to scavenge many oxidants, thereby preserving the human redox…”
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Phytochemical Variability, In Vitro and In Vivo Biological Investigations, and In Silico Antibacterial Mechanisms of Mentha piperita Essential Oils Collected from Two Different Regions in Morocco
Published in Foods (01-11-2022)“…The objective of this work is to explore the phytochemical profile of Mentha piperita essential oils (MPEO) collected from two different Moroccan regions using…”
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Alternative non-drug treatment options of the most neglected parasitic disease cutaneous leishmaniasis: A narrative review
Published in Tropical medicine and infectious disease (14-05-2023)“…With more than 12 million cases worldwide, leishmaniasis is one of the top 10 neglected tropical diseases. According to the WHO, there are approximately 2…”
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Nucleotide and nucleoside-based drugs: past, present, and future
Published in Saudi journal of biological sciences (01-12-2022)“…[Display omitted] Nucleotide and nucleoside-based analogue drugs are widely used for the treatment of both acute and chronic viral infections. These drugs…”
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Sodium alginate-based smart gastro-retentive drug delivery system of revaprazan loaded SLNs; Formulation and characterization
Published in International journal of biological macromolecules (31-12-2023)“…Revaprazan (REV), a novel reversible Proton Pump Inhibitor (PPI) used to treat peptic ulcers, faces challenges in therapeutic efficacy due to its poor…”
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Mathematical optimization and prediction of Febuxostat xanthine oxidase inhibitor solubility through supercritical CO2 system using machine-learning approach
Published in Journal of molecular liquids (01-10-2023)“…•Computational simulation framework for drug solubility.•Artificial intelligence for correlation of Febuxostat solubility in solvent.•Validation of the models…”
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Meta-Analysis and Systematic Review of HLA DQ2/DQ8 in Adults with Celiac Disease
Published in International journal of molecular sciences (07-01-2023)“…Although people with human leukocyte antigens (HLA) DQ2 and/or DQ8 are more likely to develop celiac disease (CD), the condition cannot be fully explained by…”
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Effects of Extraction Methods on the Bioactivities and Nutritional Value of Virginia and Valencia-Type Peanut Oil
Published in Molecules (Basel, Switzerland) (01-11-2022)“…This study aimed to evaluate the effects of peanut varieties cultivated in Morocco ( and ) and extraction methods (cold press, CP; Soxhlet, Sox and maceration,…”
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