Search Results - "Awadalla, P"

Depression and risk of type 2 diabetes: the potential role of metabolic factors by Schmitz, N, Deschênes, S S, Burns, R J, Smith, K J, Lesage, A, Strychar, I, Rabasa-Lhoret, R, Freitas, C, Graham, E, Awadalla, P, Wang, J L

“…The aim of the present study was to evaluate the interaction between depressive symptoms and metabolic dysregulations as risk factors for type 2 diabetes. The…”
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URINARY UROMODULIN IN A PATHWAY BETWEEN DECREASED URINARY URIC ACID EXCRETION AND ALBUMINURIA by Krajcoviechova, A, Marois-Blanchet, F, Troyanov, S, Harvey, F, Dumas, P, Tremblay, J, Cifkova, R, Awadalla, P, Madore, F, Hamet, P

“…OBJECTIVE:The mechanism explaining the inverse relationship between urinary uric acid and albumin excretion remains unclear. First, we evaluated the impact of…”
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Plasmodium falciparum Genetic Diversity Maintained and Amplified Over 5 Years of a Low Transmission Endemic in the Peruvian Amazon by Branch, OraLee H., Sutton, Patrick L., Barnes, Carmen, Castro, Juan Carlos, Hussin, Julie, Awadalla, Philip, Hijar, Gisely

“…Plasmodium falciparum entered into the Peruvian Amazon in 1994, sparking an epidemic between 1995 and 1998. Since 2000, there has been sustained low P…”
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Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome by Zilversmit, Martine M, Volkman, Sarah K, DePristo, Mark A, Wirth, Dyann F, Awadalla, Philip, Hartl, Daniel L

“…Over the past decade, attempts to explain the unusual size and prevalence of low-complexity regions (LCRs) in the proteins of the human malaria parasite…”
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Composite Effects of Rare Variants in a Novel X-Linked Form of Congenital Heart Disease in the Québec Founder Population by Preuss, C, Yang, S, Capredon, M, Samuels, M, Awadalla, P, Chetaille, P, Andelfinger, G

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Linkage Mapping and Whole-Exome Sequencing in a Family With Left Ventricular Outflow Tract Obstruction by Preuss, C, Capredon, M, Asselin, G, Dubé, M, Samuels, M, Awadalla, P, Chetaille, P, Andelfinger, G

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Impact of Rare Genetic Variations on Left Ventricular Outflow Tract Obstruction: Lessons From Whole Exome Sequencing by Capredon, M, Preuss, C, Grenier, J, Bruat, V, de Malliard, T, Leclerc, S, Privé, C, Thibeault, M, Chetaille, P, Samuel, M.E, Awadalla, P, Andelfinger, G

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Microsatellite variation and evolution in the Mimulus guttatus species complex with contrasting mating systems by Awadalla, P, Ritland, K

“…Mutational variability at microsatellite loci is shaped by both population history and the mating system. In turn, alternate mating systems in flowering plants…”
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Population-level Studies of Multiallelic Self-incompatibility Loci, with Particular Reference to Brassicaceae by Charlesworth, D., Awadalla, P., Mable, B.K., Schierup, M.H.

“…Here we review some of the unsolved problems in understanding plant self-incompatibility and attempt to show how a population genetics approach is integral to…”
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Local differentiation in Plasmodium falciparum drug resistance genes in Sudan by Abdel-Muhsin, A A, Mackinnon, M J, Awadalla, P, Ali, E, Suleiman, S, Ahmed, S, Walliker, D, Babiker, H A

“…Studies of population genetic structure of parasites can be used to infer which parasite genes are under selection. Here, the population structure of 4 genes…”
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P35 Évidence de risque accru d’ostéoporose dans le diabète et l’hypertension : importance de la masse musculaire by El Bikai, R, Dumas, P, Awadalla, P, Temblay, J, Laberge, C, Ste-Marie, L.G, Hamet, P

“…Introduction Le projet Cartagène porte sur la santé publique et la génomique de la la population Québécoise. Le but du projet est de mettre à la disposition…”
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The evolutionary genomics of pathogen recombination by Awadalla, Philip

“…A pressing problem in studying the evolution of microbial pathogens is to determine the extent to which these genomes recombine. This information is essential…”
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The relationship between reproductive lifespan and coronary artery disease by Trochet, H., Pelletier, J., Grenier, J.C., Favé, M.J., Awadalla, P., Hussin, J.

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A Coalescent-Based Method for Detecting and Estimating Recombination From Gene Sequences by McVean, Gil, Awadalla, Philip, Fearnhead, Paul

“…Determining the amount of recombination in the genealogical history of a sample of genes is important to both evolutionary biology and medical population…”
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Rare allelic forms of PRDM9 associated with childhood leukemogenesis by Hussin, Julie, Sinnett, Daniel, Casals, Ferran, Idaghdour, Youssef, Bruat, Vanessa, Saillour, Virginie, Healy, Jasmine, Grenier, Jean-Christophe, de Malliard, Thibault, Busche, Stephan, Spinella, Jean-François, Larivière, Mathieu, Gibson, Greg, Andersson, Anna, Holmfeldt, Linda, Ma, Jing, Wei, Lei, Zhang, Jinghui, Andelfinger, Gregor, Downing, James R, Mullighan, Charles G, Awadalla, Philip

“…One of the most rapidly evolving genes in humans, PRDM9, is a key determinant of the distribution of meiotic recombination events. Mutations in this…”
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Recombination hotspots and population structure in Plasmodium falciparum by Mu, Jianbing, Awadalla, Philip, Duan, Junhui, McGee, Kate M, Joy, Deirdre A, McVean, Gilean A T, Su, Xin-zhuan

“…Understanding the influences of population structure, selection, and recombination on polymorphism and linkage disequilibrium (LD) is integral to mapping genes…”
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The impact of reporting magnetic resonance imaging incidental findings in the Canadian alliance for healthy hearts and minds cohort by Luu, Judy M, Sergeant, Anand K, Anand, Sonia S, Desai, Dipika, Schulze, Karleen, Knoppers, Bartha M, Zawati, Ma'n H, Smith, Eric E, Moody, Alan R, Black, Sandra E, Larose, Eric, Marcotte, Francois, Kleiderman, Erika, Tardif, Jean-Claude, Lee, Douglas S, Friedrich, Matthias G, Anand, S, Friedrich, M, Tu, J, Awadalla, P, Dummer, T, Vena, J, Broet, P, Hicks, J, Tardif, J.-C, Teo, K, Knoppers, B.-M, Desai, D, Nandakumar, S, Thomas, M, Zafar, S, Schulze, K, Dyal, L, Casanova, A, Bangdiwala, S, Ramasundarahettige, C, Ramakrishnana, K, Ibrahim, Q, Truchon, H, Tusevljak, N, McDonald, K, Noisel, N, Chu, J, Whelan, H, Rangarajan, S, Busseuil, D, Leipsic, J, Lear, S, de Jong, V, Noseworthy, M, Ramezani, E, Konyer, N, Poirier, P, Bourlaud, A.-S, Larose, E, Bibeau, K, Smith, E, Frayne, R, Charlton, A, Sekhon, R, Moody, A, Thayalasuthan, V, Kripalani, A, Leung, G, de Souza, R, Paraga, G, Reid, L, Dick, A, Ahmad, F, Kelton, D, Shah, H, Marcotte, F, Poiffaut, H, Lebel, J, Miller, R, Parker, L, Thompson, D, Chan, K, McCreary, C, Black, S. E, Scott, C, Batool, S, Gao, F, Henriques, F, Rouleau, Jean, Boyle, Pierre, Wong, Caroline, Smith, Eldon, Reid, Bob, Janssen, Ian, Subar, Amy, Touyz, Rhian

“…Abstract Background In the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain,…”
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Linkage Disequilibrium and Recombination in Hominid Mitochondrial DNA by Awadalla, Philip, Eyre-Walker, Adam, Smith, John Maynard

“…The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable. Linkage disequilibrium in human…”
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Phenotypic Variation and Natural Selection at Catsup, a Pleiotropic Quantitative Trait Gene in Drosophila by Carbone, Mary Anna, Jordan, Katherine W., Lyman, Richard F., Harbison, Susan T., Leips, Jeff, Morgan, Theodore J., DeLuca, Maria, Awadalla, Philip, Mackay, Trudy F.C.

“…Quantitative traits are shaped by networks of pleiotropic genes [1]. To understand the mechanisms that maintain genetic variation for quantitative traits in…”
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Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus by Barbash, Daniel A, Awadalla, Philip, Tarone, Aaron M

“…Interspecific hybrid lethality and sterility are a consequence of divergent evolution between species and serve to maintain the discrete identities of species…”
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