Search Results - "Awad, Eman M."

Dihydromyricetin alleviates methotrexate-induced hepatotoxicity via suppressing the ‎TLR4/NF-κB pathway and NLRP3 inflammasome/caspase 1 axis by Matouk, Asmaa I., Awad, Eman M., El-Tahawy, Nashwa F.G., El-Sheikh, Azza A.K., Waz, Shaimaa

“…The anticancer drug methotrexate (MTX) is known to cause hepatotoxicity as a possibly fatal adverse effect that hinders its clinical application. Although the…”
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Dihydromyricetin protects against high glucose-induced endothelial dysfunction: Role of HIF-1α/ROR2/NF-κB by Awad, Eman M., Ahmed, Al-Shaimaa F., El-Daly, Mahmoud, Amin, Ali H., El-Tahawy, Nashwa F.G., Wagdy, AlShimaa, Hollenberg, Morley D., Taye, Ashraf

“…Dihydromyricetin (DHM), a natural flavonoid isolated from vine tea with anti-inflammatory activity was evaluated for its ability to prevent vascular…”
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Dihydromyricetin Modulates Nrf2 and NF-κB Crosstalk to Alleviate Methotrexate-Induced Lung Toxicity by Matouk, Asmaa I, Awad, Eman M, El-Tahawy, Nashwa F G, El-Sheikh, Azza A K, Anter, Aliaa

“…Methotrexate (MTX) is an effective anticancer, anti-inflammatory, and immunomodulatory agent. However, it induces a serious pneumonitis that leads to…”
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Dihydromyricetin protects against gentamicin-induced nephrotoxicity via upregulation of renal SIRT3 and PAX2 by Matouk, Asmaa I, Awad, Eman M, Mousa, Amr A K, Abdelhafez, Sara M N, Fahmy, Usama A, El-Moselhy, Mohamed A, Abdel-Naim, Ashraf B, Anter, Aliaa

“…Gentamicin-induced nephrotoxicity limits its widespread use as an effective antibacterial agent. Oxidative stress, inflammatory cytokines and apoptotic cell…”
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Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity by Ragab, Mahmoud A., Elagawany, Mohamed, Daabees, Hoda, Ahmed, Al-Shaimaa F., Awad, Eman M., Billon, Cyrielle, Elgendy, Bahaa, Abouzid, Khaled A.M., Kassab, Shaymaa E.

“…[Display omitted] •A new chemotype of full estrogen receptor antagonist activity is identified.•The adopted drug development strategy transformed MPP drug from…”
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Vanillin-Based Indolin-2-one Derivative Bearing a Pyridyl Moiety as a Promising Anti-Breast Cancer Agent via Anti-Estrogenic Activity by Bender, Onur, Celik, Ismail, Dogan, Rumeysa, Atalay, Arzu, Shoman, Mai E., Ali, Taha F. S., Beshr, Eman A. M., Mohamed, Mahmoud, Alaaeldin, Eman, Shawky, Ahmed M., Awad, Eman M., Ahmed, Al-Shaimaa F., Younes, Kareem M., Ansari, Mukhtar, Anwar, Sirajudheen

“…The structure-based design introduced indoles as an essential motif in designing new selective estrogen receptor modulators employed for treating breast…”
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