Search Results - "Avraam, Joanne"
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0450 Genioglossus Motor Control During Mandibular Advancement and Inspiratory Resistive Loading
Published in Sleep (New York, N.Y.) (20-04-2024)“…Abstract Introduction High activity of the genioglossus muscle is thought to prevent/resolve upper airway collapse. The individual motor units that make up the…”
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Perinatal Nicotine Reduces Chemosensitivity of Medullary 5-HT Neurons after Maturation in Culture
Published in Neuroscience (15-10-2020)“…•Prenatal nicotine alters development of acidosis response in medullary 5-HT neurons.•Prenatal nicotine blunts the acidosis response of cultured medullary 5-HT…”
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3
Breathlessness, but not breathing instability varies with posttraumatic stress symptoms in University students
Published in Journal of applied physiology (1985) (01-11-2024)“…Obstructive sleep apnoea (OSA) is a chronic sleep-related breathing disorder that is highly prevalent in individuals with posttraumatic stress disorder (PTSD)…”
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4
Mechanisms underlying the prolonged activation of the genioglossus following arousal from sleep
Published in Sleep (New York, N.Y.) (11-01-2024)“…Abstract Study Objectives Transient arousal from sleep has been shown to elicit a prolonged increase in genioglossus muscle activity that persists following…”
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The effect of sex and body weight on lung volumes during sleep
Published in Sleep (New York, N.Y.) (01-10-2019)“…Low lung volumes are thought to contribute to obstructive sleep apnea (OSA). OSA is worse in the supine versus lateral body position, men versus women, obese…”
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6
The influence of alcohol on genioglossus single motor units in men and women during wakefulness
Published in Experimental physiology (01-03-2023)“…New Findings What is the central question of this study? How does alcohol intake, which worsens obstructive sleep apnoea, alter motor control of the…”
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7
After-discharge in the upper airway muscle genioglossus following brief hypoxia
Published in Sleep (New York, N.Y.) (01-09-2021)“…Abstract Study Objectives Genioglossus (GG) after-discharge is thought to protect against pharyngeal collapse by minimizing periods of low upper airway muscle…”
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α4-Containing nicotinic receptors contribute to the effects of perinatal nicotine on ventilatory and metabolic responses of neonatal mice to ambient cooling
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-10-2016)“…Among numerous studies, perinatal nicotine exposure (PN) has had variable effects on respiratory control in the neonatal period. The effects of acute nicotine…”
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The effects of chronic nicotine exposure on chemosensitivity of medullary 5‐HT neurons
Published in The FASEB journal (01-04-2012)“…Abstract only 5‐HT neurons are chemoreceptive and involved in respiratory control. SIDS has been linked to brainstem 5‐HT abnormalities, fetal nicotine…”
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The effect of body mass and sex on the accuracy of respiratory magnetometers for measurement of end-expiratory lung volumes
Published in Journal of applied physiology (1985) (01-11-2016)“…Respiratory magnetometers are increasingly being used in sleep studies to measure changes in end-expiratory lung volume (EELV), including in obese obstructive…”
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The Effects of Experimental Sleep Fragmentation and Sleep Deprivation on the Response of the Genioglossus Muscle to Inspiratory Resistive Loads
Published in Journal of clinical sleep medicine (15-05-2018)“…Poor upper airway dilator muscle function may contribute to obstructive sleep apnea (OSA). Sleep deprivation reduces dilator muscle responsiveness, but sleep…”
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Maintenance of convective requirement during recovery from moderate heat stress in newborn mice
Published in The FASEB journal (2007)“…Hypothermia often provides a regulated protective mechanism that improves survival. In contrast, overheating may result in disruption of cerebral function,…”
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Prenatal nicotine exposure increases hyperventilation in α4-knock-out mice during mild asphyxia
Published in Respiratory physiology & neurobiology (01-03-2015)“…Highlights • The role of α4-containing nAChRs in neonatal respiratory control in vivo has never been explored. • At P1-2, nicotine reduces V ˙ E and V ˙ O 2…”
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Prenatal nicotine exposure causes differential impairment of thermogenesis and ventilation in neonatal WT and α4 KO mice
Published in FASEB JOURNAL (01-04-2011)“…Prenatal nicotine exposure impairs functions necessary for neonatal survival. A mechanism may involve disruption of nicotine acetylcholine receptor‐mediated…”
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Does Nasal Obstruction Induce Obstructive Sleep Apnea in Healthy Women?
Published in Nature and science of sleep (30-06-2020)“…Obstructive sleep apnea (OSA) is less prevalent among women and is associated with different symptoms and consequences to OSA in men. The reasons for these…”
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