Search Results - "Avorn, J."

Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs: population based cohort study by Huybrechts, K F, Gerhard, T, Crystal, S, Olfson, M, Avorn, J, Levin, R, Lucas, J A, Schneeweiss, S

“…Objective To assess risks of mortality associated with use of individual antipsychotic drugs in elderly residents in nursing homes.Design Population based…”
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Statins and congenital malformations: cohort study by Bateman, Brian T, Hernandez-Diaz, Sonia, Fischer, Michael A, Seely, Ellen W, Ecker, Jeffrey L, Franklin, Jessica M, Desai, Rishi J, Allen-Coleman, Cora, Mogun, Helen, Avorn, Jerry, Huybrechts, Krista F

“…Objective To examine the teratogenic potential of statins.Design Cohort study.Setting United States.Participants A cohort of 886 996 completed pregnancies…”
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Defining the epidemiology of bisphosphonate-associated osteonecrosis of the jaw: prior work and current challenges by Solomon, D. H., Mercer, E., Woo, S. B., Avorn, J., Schneeweiss, S., Treister, N.

“…Summary Bisphosphonate-related osteonecrosis of the jaw (BONJ) is an adverse effect of bisphosphonate use with a poorly described epidemiology in osteoporosis…”
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Patterns of cardiovascular risk in rheumatoid arthritis by Solomon, D H, Goodson, N J, Katz, J N, Weinblatt, M E, Avorn, J, Setoguchi, S, Canning, C, Schneeweiss, S

“…Background: Although it is known that rheumatoid arthritis is associated with an increased risk of cardiovascular disease (CVD), the pattern of this risk is…”
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Defining "Innovativeness" in Drug Development: A Systematic Review by Kesselheim, A S, Wang, B, Avorn, J

“…Some observers of drug development argue that the pace of pharmaceutical innovation is declining, but others deny that contention. This controversy may be due…”
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Uric acid lowering therapy: prescribing patterns in a large cohort of older adults by Solomon, D H, Avorn, J, Levin, R, Brookhart, M A

“…Uric acid lowering therapy (UALT) is considered a chronic treatment for gout. Relatively little is known about adherence to UALT. We assessed adherence with…”
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Adherence to Lipid-lowering Therapy and the Use of Preventive Health Services: An Investigation of the Healthy User Effect by Brookhart, M. Alan, Patrick, Amanda R., Dormuth, Colin, Avorn, Jerry, Shrank, William, Cadarette, Suzanne M., Solomon, Daniel H.

“…Patients who adhere to preventive therapies may be more likely to engage in a broad spectrum of behaviors consistent with a healthy lifestyle. Because many of…”
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Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults by SOLOMON, Daniel H, SCHNEEWEISS, Sebastian, GLYNN, Robert J, KIYOTA, Yuka, LEVIN, Raisa, MOGUN, Helen, AVORN, Jerry

“…Although cyclooxygenase-2 inhibitors (coxibs) were developed to cause less gastrointestinal hemorrhage than nonselective nonsteroidal antiinflammatory drugs…”
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Refilling and Switching of Antiepileptic Drugs and Seizure-Related Events by Gagne, J J, Avorn, J, Shrank, W H, Schneeweiss, S

“…We sought to estimate the risk of seizure‐related events associated with refilling prescriptions for antiepileptic drugs (AEDs) and to estimate the effect of…”
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Drug Labels: A Flawed Source of Data for Studying Orphan Drug Approvals by Kesselheim, A S, Avorn, J

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Clinical and Regulatory Features of Drugs Not Initially Approved by the FDA by Wang, B, Avorn, J, Kesselheim, A S

“…US Food and Drug Administration (FDA) denials of New Drug Applications (NDAs) are often controversial, yet little is known about the basis and characteristics…”
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Trends in direct-to-consumer advertising for prescription contraceptives by Wu, M, Seeger, J, Bartz, D, Avorn, J

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FDA Standards — Good Enough for Government Work? by Avorn, Jerry

“…Dr. Jerry Avorn explains that there is one area of biomedicine in which the government allows — even defends — a minimal standard that would be unacceptable…”
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Interventions to improve adherence and persistence with osteoporosis medications: a systematic literature review by Gleeson, T, Iversen, M. D, Avorn, J, Brookhart, A. M, Katz, J. N, Losina, E, May, F, Patrick, A. R, Shrank, W. H, Solomon, D. H

“…Summary Adherence and persistence with osteoporosis medications are poor. We conducted a systematic literature review of interventions to improve adherence and…”
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Improving Drug Use in Elderly Patients: Getting to the Next Level by Avorn, Jerry

“…The use of modern data management approaches to assess and improve drug use in elderly patients will soon move beyond cutting-edge settings to office practices…”
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Cultural and economic factors that (mis)shape antibiotic use : The nonpharmacologic basis of therapeutics by AVORN, J, SOLOMON, D. H

“…The use of antibiotics in both ambulatory and inpatient settings is heavily shaped by cultural and economic factors as well as by microbiological…”
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Are Risk Evaluation and Mitigation Strategies Associated With Less Off-Label Use of Medications? The Case of Immune Thrombocytopenia by Sarpatwari, A, Franklin, JM, Avorn, J, Seeger, JD, Landon, JE, Kesselheim, AS

“…Using data from a large commercial health insurer, we studied prescribing of romiplostim (Nplate) and eltrombopag (Promacta), two drugs for primary immune…”
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Medicaid Prior-Authorization Programs and the Use of Cyclooxygenase-2 Inhibitors by Fischer, Michael A, Schneeweiss, Sebastian, Avorn, Jerry, Solomon, Daniel H

“…To control costs, some state Medicaid programs have implemented policies requiring prior approval before a selective cyclooxygenase-2 inhibitor (coxib) can be…”
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Hazardous Benzodiazepine Regimens in the Elderly: Effects of Half-Life, Dosage, and Duration on Risk of Hip Fracture by Wang, Philip S., Bohn, Rhonda L., Glynn, Robert J., Mogun, Helen, Avorn, Jerry

“…OBJECTIVE: While benzodiazepine treatment is known to increase the risk of hip fracture in older populations, controversy persists over which characteristics…”
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Quality indicators for appropriate medication use in vulnerable elders by Knight, E L, Avorn, J

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