Search Results - "Avoort, Irene A. M."

Long‐term consequences of juvenile vulvar lichen sclerosus: A cohort study of adults with a histologically confirmed diagnosis in childhood or adolescence by Morrel, Beth, Avoort, Irene A. M., Ewing‐Graham, Patricia C., Damman, Jeffrey, Schappin, Renske, Zeijl, Kelly N., Voorham, Quirinus J. M., Esajas, Martha D., Oom, Daniella M. J., Vleeschouwer, Marloes L. H. M., Mous, Marieke, Salvatore, Concetta M., Leeuwen, Jeanette, Bais, Joke M. J., Bassie‐Minderhoud, Willy, Dijkstra, Jeroen R., Geukes, Marije, Grinsven‐Dmitrieva, Nadja N., Janssen, Ineke C. A. H., Joostens, Mieke A. M., Kagie, Marjolein J., Klompmaker, Esther R., Lammerink, Ellen A. G., Lardenoije, Celine M. J. G., Lenselink, Charlotte H., Louwers, Jacqueline A., Maassen, Marloes S., Mierlo, Kim M. C., Nelissen, Ewka C. M., Piscaer‐van Eijsden, Claire J. A., Polderman, Marloes C. A., Salm, Paulien C. M., Santegoets, Lindy A. M., Traas‐Hofmans, Maaike A. F., Wassen, Martine M. L. H., Wijk, Heidy F. H., Kate‐Booij, Marianne J., Burger, Curt W., Pasmans, Suzanne G. M. A.

“…Introduction Vulvar lichen sclerosus (VLS) occurs in at least one in 900 girls. There is limited knowledge as to what extent the disease persists in adulthood…”
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Tread carefully when considering vulvar melanoma in a child or adolescent by Morrel, Beth, Pasmans, Suzanne G. M. A., Mooyaart, Antien L., Avoort, Irene A. M.

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Vulvar squamous cell carcinoma development after diagnosis of VIN increases with age by van de Nieuwenhof, Hedwig P, Massuger, Leon F.A.G, van der Avoort, Irene A.M, Bekkers, Ruud L.M, Casparie, Mariel, Abma, Wim, van Kempen, Léon C.L.T, de Hullu, Joanne A

“…Abstract Objective The purpose of the present study is to investigate the trends in incidence of both usual (u) and differentiated (d) vulvar intraepithelial…”
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High levels of p53 expression correlate with DNA aneuploidy in (pre)malignancies of the vulva by van der Avoort, Irene A.M., MD, MSc, van de Nieuwenhof, Hedwig P., MD, Otte-Höller, Irene, MSc, Nirmala, Ella, BSc, Bulten, Johan, MD, PhD, Massuger, Leon F.A.G., MD, PhD, van der Laak, Jeroen A.W.M., PhD, Slootweg, Piet J., MD, PhD, de Hullu, Joanne A., MD, PhD, van Kempen, Léon C.L.T., PhD

“…Summary The molecular pathogenesis of human papilloma virus–unrelated vulvar squamous cell carcinoma is not well known. Whether malignant progression of lichen…”
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Structured analysis of histopathological characteristics of vulvar lichen sclerosus in a juvenile population by Morrel, Beth, Ewing-Graham, Patricia C., van der Avoort, Irene A.M., Pasmans, Suzanne G.M.A., Damman, Jeffrey

“…Genital lichen sclerosus (LS), a chronic noninfectious dermatosis, is not rare in pediatric dermatology. The histopathological diagnosis in children and adults…”
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HPV and DNA Methylation Testing in Urine for Cervical Intraepithelial Neoplasia and Cervical Cancer Detection by van den Helder, Rianne, Steenbergen, Renske D M, van Splunter, Annina P, Mom, Constantijne H, Tjiong, Ming Y, Martin, Ivonne, Rosier-van Dunné, Fleur M F, van der Avoort, Irene A M, Bleeker, Maaike C G, van Trommel, Nienke E

“…Biomarker detection in urine offers a potential solution to increase effectiveness of cervical cancer screening programs by attracting nonresponders. In this…”
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The long-term clinical consequences of juvenile vulvar lichen sclerosus: A systematic review by Morrel, Beth, van Eersel, Rachel, Burger, Curt W., Bramer, Wichor M., ten Kate-Booij, Marianne J., van der Avoort, Irene A.M., Pasmans, Suzanne G.M.A.

“…Vulvar lichen sclerosus (VLS) occurring in children and adolescents may have repercussions throughout life. We sought to assess the evidence available on the…”
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Growing up with juvenile vulvar lichen sclerosus: the experiences and care needs of adult women with lichen sclerosus since childhood - a qualitative exploration by Morrel, Beth, Kampherbeek, H Janneke, Ten Kate-Booij, Marianne J, van der Avoort, Irene A M, van Hees, Colette L M, Wigny, Kiki M G J, Burger, Curt W, Pasmans, Suzanne G M A, Lugtenberg, Marjolein

“…Vulvar lichen sclerosus (VLS) is a chronic remitting condition that affects the genital skin of females of all ages. Although qualitative studies have been…”
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The prognostic value of blood and lymph vessel parameters in lichen sclerosus for vulvar squamous cell carcinoma development: an immunohistochemical and electron microscopy study by van der Avoort, Irene A.M., MD, MSc, van der Laak, Jeroen A.W.M., PhD, Otte-Höller, Irene, MSc, van de Nieuwenhof, Hedwig P., MD, MSc, Massuger, Leon F.A.G., MD, PhD, de Hullu, Joanne A., MD, PhD, van Kempen, Léon C.L.T., PhD

“…Objective The objective of the study was to quantify vessel type and density in lichen sclerosus (LS) to find a marker for its malignant potential. Study…”
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Outcome Measures in Adult Vulvar Lichen Sclerosus: A Systematic Review by Morrel, Beth, Ten Kate-Booij, Marianne J, van Dijk, Charlotte, Bramer, Wichor M, Burger, Curt W, Pasmans, Suzanne G M A, van der Avoort, Irene A M

“…Core outcome domains (CODs) for treatment of adult vulvar lichen sclerosus (VLS) have recently been established through a Delphi study. A number of measuring…”
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Outcome Measures in Adult Vulvar Lichen Sclerosus: A Case Series of Women Diagnosed as Juveniles by Morrel, Beth, Ten Kate-Booij, Marianne J, van Dijk, Charlotte, van Hees, Colette L M, Wigny, Kiki M G J, Burger, Curt W, Pasmans, Suzanne G M A, van der Avoort, Irene A M

“…Studies on the consequences of juvenile vulvar lichen sclerosus (JVLS) in adulthood are limited. A number of measuring tools are available for analyzing adult…”
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Relationship of human papillomavirus with seborrheic keratosis of the female genital tract - a case-series and literature review by Dasgupta, Shatavisha, van Eersel, Rachel, Morrel, Beth, van den Munckhof, Henk A M, de Geus, Vera A, van der Hoeven, Nick M A, van de Sandt, Miekel M, Piso-Jozwiak, Marta, Quint, Wim G V, van der Avoort, Irene A M, Koljenović, Senada, Ewing-Graham, Patricia C, van Kemenade, Folkert J

“…Seborrheic keratoses (SKs) are benign lesions of uncertain etiology, which can develop in both genital and extra-genital locations. For genital SKs, there has…”
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Phenotypic Characteristics of Male Subfertility and Its Familial Occurrence by van Golde, Ron J. T, van der Avoort, Irene A. M, Tuerlings, Joep H. A. M, Kiemeney, Lambertus A, Meuleman, Eric J. H, Braat, Didi D. M, Kremer, Jan A. M

“…Genetic factors can attribute to male subfertility. A case‐control study was carried out to investigate familial occurrence of male subfertility and the…”
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MIB1 expression in basal cell layer: a diagnostic tool to identify premalignancies of the vulva by van der Avoort, Irene A M, van der Laak, Jeroen A W M, Paffen, Ard, Grefte, Johanna M M, Massuger, Leon F A G, de Wilde, Peter C M, de Hullu, Joanne A, Bulten, Johan

“…Lichen sclerosus, high-grade usual vulvar intraepithelial neoplasia (VIN) and differentiated VIN have a different malignant potential. The objective of this…”
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A panel of p16(INK4A), MIB1 and p53 proteins can distinguish between the 2 pathways leading to vulvar squamous cell carcinoma by Hoevenaars, Brigiet M, van der Avoort, Irene A M, de Wilde, Peter C M, Massuger, Leon F A G, Melchers, Willem J G, de Hullu, Joanne A, Bulten, Johan

“…Two pathways leading to vulvar squamous cell carcinoma (SCC) exist. The expression of proliferation- and cell-cycle-related biomarkers and the presence of…”
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Experiences and preferences towards collecting a urine and cervicovaginal self-sample among women attending a colposcopy clinic by Schaafsma, Mirte, van den Helder, Rianne, Bleeker, Maaike C.G., Rosier-van Dunné, Fleur, van der Avoort, Irene A.M., Steenbergen, Renske D.M., van Trommel, Nienke E.

“…•In a colposcopy referral population, the majority of women consider self-collection of a urine sample and a cervicovaginal self-sample acceptable and easy to…”
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A patient with lichen sclerosus, Langerhans cell histiocytosis, and invasive squamous cell carcinoma of the vulva by Simons, Michiel, MD, Van De Nieuwenhof, Hedwig P., MD, Van Der Avoort, Irene A.M., MD, Bulten, Johan, MD, PhD, De Hullu, Joanne A., MD, PhD

“…We report a patient with vulvar lichen sclerosus, Langerhans cell histiocytosis (LCH), and later vulvar cancer. In LCH, high amounts of non functional…”
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Prevention, identification and treatment of vulvar squamous (pre)malignancies: a review focusing on quality of care by van den Einden, Loes CG, van der Avoort, Irene AM, de Hullu, Joanne A

“…Vulvar squamous cell carcinoma, its precursor lesions (usual and differentiated vulvar intraepithelial neoplasia) and lichen sclerosus are rare diseases that…”
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A panel of p16INK4A, MIB1 and p53 proteins can distinguish between the 2 pathways leading to vulvar squamous cell carcinoma by Hoevenaars, Brigiet M., van der Avoort, Irene A.M., de Wilde, Peter C.M., Massuger, Leon F.A.G., Melchers, Willem J.G., de Hullu, Joanne A., Bulten, Johan

“…Two pathways leading to vulvar squamous cell carcinoma (SCC) exist. The expression of proliferation‐ and cell‐cycle‐related biomarkers and the presence of…”
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Lichen sclerosus: treatment and follow-up at the departments of gynaecology and dermatology by van der Avoort, Irene A M, Tiemes, Demia E M, van Rossum, Michelle M, van der Vleuten, Carine J M, Massuger, Leon F A G, de Hullu, Joanne A

“…To compare the treatment and follow-up of patients with lichen sclerosus (LS) at the departments of Gynaecology and Dermatology at the Radboud University…”
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