Search Results - "Avkiran, M"

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    Blowing off acid: a new tool to study Na + /HCO 3 − co‐transport by Avkiran, M

    Published in British journal of pharmacology (29-01-2009)
    “…Investigation of the physiological functions and possible pathological roles of Na + /HCO 3 − co‐transport in the heart has been hampered by uncertainty over…”
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    Journal Article
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    Blowing off acid: a new tool to study Na+/HCO3− co‐transport by Avkiran, M

    Published in British journal of pharmacology (01-03-2008)
    “…Investigation of the physiological functions and possible pathological roles of Na+/HCO3− co‐transport in the heart has been hampered by uncertainty over the…”
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    Journal Article
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    Legumain and cathepsin-L expression in human unstable carotid plaque by Mattock, K.L, Gough, P.J, Humphries, J, Burnand, K, Patel, L, Suckling, K.E, Cuello, F, Watts, C, Gautel, M, Avkiran, M, Smith, A

    Published in Atherosclerosis (01-01-2010)
    “…Abstract Objective The cysteine protease, legumain, is thought to have a role in the processing and activation of proteases such as cathepsin-L, which have…”
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    Effects of moderate hypothermia on sarcolemmal Na+/H+ exchanger activity and its inhibition by cariporide in cardiac ventricular myocytes by Hoshino, Kimihiko, Avkiran, Metin

    Published in British journal of pharmacology (01-12-2001)
    “…Specific inhibitors of the sarcolemmal Na+/H+ exchanger (NHE) such as cariporide are being evaluated for cardioprotective therapy during cardiac surgery. We…”
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    Na+/H+ exchange and reperfusion arrhythmias: protection by intracoronary infusion of a novel inhibitor by Yasutake, M, Ibuki, C, Hearse, D J, Avkiran, M

    Published in The American journal of physiology (01-12-1994)
    “…Activation of sarcolemmal Na+/H+ exchange has been proposed as a causal factor in reperfusion arrhythmogenesis. To test this hypothesis, we determined the…”
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    Na+/Ca2+ exchange current density in cardiac myocytes from rabbits and guinea pigs during postnatal development by Artman, M, Ichikawa, H, Avkiran, M, Coetzee, W A

    Published in The American journal of physiology (01-04-1995)
    “…It has been proposed that the activity of the cardiac sarcolemmal Na+/Ca2+ exchanger may be greatest in developing animals before the sarcoplasmic reticulum…”
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    Impact of extracellular buffer composition on cardioprotective efficacy of Na+/H+ exchanger inhibitors by Shimada, Y, Hearse, D J, Avkiran, M

    Published in The American journal of physiology (01-02-1996)
    “…There is controversy over whether the cardioprotective effects of Na+/H+ exchanger inhibitors are exerted primarily during ischemia or during subsequent…”
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    Reperfusion-Induced Arrhythmias: A Role for Washout of Extracellular Protons? by Avkiran, Metin, Ibuki, Chikao

    Published in Circulation research (01-12-1992)
    “…Rapid washout of extracellular H accumulated during preceding ischemia (i.e., the abrupt restoration of extracellular pH) has been implicated as an…”
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    Targeting Na+ /H+ exchanger regulation for cardiac protection: a RSKy approach? by Avkiran, Metin, Cook, Alexandra R, Cuello, Friederike

    Published in Current opinion in pharmacology (01-04-2008)
    “…Extensive pre-clinical work indicates that inhibition of the Na+ /H+ exchanger (NHE) affords significant protection to myocardium subjected to ischaemia and…”
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    Effects of acidic reperfusion on arrhythmias and Na(+)-K(+)-ATPase activity in regionally ischemic rat hearts by Avkiran, M, Ibuki, C, Shimada, Y, Haddock, P S

    Published in The American journal of physiology (01-03-1996)
    “…We studied the effects of acidic reperfusion on 1) the incidence of ventricular fibrillation (VF) and 2) sarcolemmal Na(+)-K(+)-adenosinetriphosphatase…”
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