Search Results - "Avilés, P"
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Use of air stacking and abdominal compression for cough assistance in people with complete tetraplegia
Published in Spinal cord (01-05-2014)“…Study design: Cross-sectional. Objective: To assess cough using air stacking (AS) to assist inspiratory volume with abdominal compression (AC) during…”
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2
Development and validation of a liquid chromatography-tandem mass spectrometry assay for the quantification of lurbinectedin in human plasma and urine
Published in Journal of pharmaceutical and biomedical analysis (05-09-2018)“…•A rapid and sensitive LC–MS/MS method developed to quantify lurbinectedin in human plasma and urine.•The assay has successfully been validated in the 0.1–100…”
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3
Liquid chromatography-tandem mass spectrometry assay to quantify plitidepsin in human plasma, whole blood and urine
Published in Journal of pharmaceutical and biomedical analysis (25-10-2017)“…•A bioanalytical assay was developed for plitidepsin in plasma, whole blood and urine using HPLC–MS/MS.•The first reported bioanalytical assay for the…”
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4
Metabolite profiling of the novel anti-cancer agent, plitidepsin, in urine and faeces in cancer patients after administration of 14C-plitidepsin
Published in Cancer chemotherapy and pharmacology (01-09-2018)“…Purpose Plitidepsin absorption, distribution, metabolism and excretion characteristics were investigated in a mass balance study, in which six patients…”
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5
MI130110, a new antibody–drug conjugate combining an anti-CD13 antibody and a payload of marine origin shows remarkable in vivo activity
Published in European journal of cancer (1990) (01-12-2016)“…Background: CD13 is a Zn-dependent ectopeptidase involved in the modulation of several vasoactive peptides and known to influence major biological events such…”
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6
Comparison of pharmacokinetic profiles of PM02734 loaded lipid nanoparticles and cyclodextrins: in vitro and in vivo characterization
Published in Journal of biomedical nanotechnology (01-08-2012)“…PM02734 is a chemically synthesized depsipeptide derived from the marine kahalalides family with a broad spectrum of activity against solid tumors in vitro and…”
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7
Using LiF:Mg,Cu,P TLDs to estimate the absorbed dose to water in liquid water around an 192Ir brachytherapy source
Published in Medical physics (Lancaster) (01-01-2014)“…Purpose: The absorbed dose to water is the fundamental reference quantity for brachytherapy treatment planning systems and thermoluminescence dosimeters (TLDs)…”
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8
A multi-objective evolutionary approach for planning and optimal condition restoration of secondary distribution networks
Published in Applied soft computing (01-05-2020)“…A secondary distribution network (SDN), corresponding to the final user low voltage distribution circuit, is continuously growing due to a persistent increase…”
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Using LiF:Mg,Cu,P TLDs to estimate the absorbed dose to water in liquid water around an $^{192}$Ir brachytherapy source
Published in Medical physics (Lancaster) (2014)“…Purpose:The absorbed dose to water is the fundamental reference quantity for brachytherapy treatment planning systems and thermoluminescence dosimeters (TLDs)…”
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10
PM01183, a new DNA minor groove covalent binder with potent in vitro and in vivo anti‐tumour activity
Published in British journal of pharmacology (01-11-2010)“…BACKGROUND AND PURPOSE PM01183 is a new synthetic tetrahydroisoquinoline alkaloid that is currently in phase I clinical development for the treatment of solid…”
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Review: Placental adaptations to the presence of maternal asthma during pregnancy
Published in Placenta (Eastbourne) (01-06-2017)“…Abstract Asthma is a highly prevalent chronic medical condition affecting an estimated 12% of pregnant, women each year, with prevalence of asthma greatest (up…”
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12
S-p-bromobenzyl-glutathione cyclopentyl diester (BBGC) as novel therapeutic strategy to enhance trabectedin anti-tumor effect in soft tissue sarcoma preclinical models
Published in Oncogene (27-09-2024)“…Trabectedin, approved for the treatment of soft tissue sarcoma (STS), interferes with cell division and genetic transcription processes. Due to its strong…”
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13
Estimation of the peak entrance surface air kerma for patients undergoing computed tomography-guided procedures
Published in Radiation protection dosimetry (01-01-2005)“…The purpose of this work was to develop a method for estimating the patient peak entrance surface air kerma from measurements using a pencil ionisation chamber…”
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14
Monte Carlo simulations in CT for the study of the surface air kerma and energy imparted to phantoms of varying size and position
Published in Physics in medicine & biology (21-04-2004)“…A Monte Carlo computational model of CT has been developed and used to investigate the effect of various physical factors on the surface air kerma length…”
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15
Evaluation of different configurations of hybrid membrane bioreactors for treatment of domestic wastewater
Published in Water science and technology (01-01-2015)“…Four membrane bioreactors (MBRs) with the same dimensions were studied for 180 days: three hybrid growth membrane bioreactors with biofilm attached in…”
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16
Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
Published in Drug metabolism and disposition (01-04-2022)“…Lurbinectedin is a novel and potent selective inhibitor of active transcription of protein-coding genes, triggering apoptosis of cancerous cells. It has been…”
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17
Assessing the visual quality of rural landscapes
Published in Landscape and urban planning (15-07-2004)“…This paper presents a methodology for assessing the visual quality of agricultural landscapes through direct and indirect techniques of landscape valuation…”
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Treatment of experimental endocarditis due to methicillin-susceptible or methicillin-resistant Staphylococcus aureus with trimethoprim-sulfamethoxazole and antibiotics that inhibit cell wall synthesis
Published in Antimicrobial Agents and Chemotherapy (01-04-1995)“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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19
Response of radiochromic dye films to low energy heavy charged particles
Published in Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms (01-12-2002)“…We have studied the possible use of radiochromic dye films (RCF) as heavy charged particle dosemeters. We present the results of irradiating two commercial RCF…”
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20
Development of a new method for the quantitation of metabolites in the absence of chemically synthetized authentic standards
Published in Journal of pharmaceutical and biomedical analysis (30-05-2019)“…•A new method to assess the absolute concentration of metabolites in the absence of chemically synthetized authentic standard was developed.•The method was…”
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