Search Results - "Avijit, Banik"
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Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models
Published in Journal of medicinal chemistry (13-02-2020)“…Activation of prostanoid EP2 receptor exacerbates neuroinflammatory and neurodegenerative pathology in central nervous system diseases such as epilepsy,…”
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A Novel Second-Generation EP2 Receptor Antagonist Reduces Neuroinflammation and Gliosis After Status Epilepticus in Rats
Published in Neurotherapeutics (01-04-2021)“…Prostaglandin-E 2 (PGE 2 ), an important mediator of inflammation, achieves its functions via four different G protein–coupled receptors (EP1, EP2, EP3, and…”
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Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer's disease
Published in Journal of neuroinflammation (20-11-2021)“…Alzheimer's disease (AD) causes substantial medical and societal burden with no therapies ameliorating cognitive deficits. Centralized pathologies involving…”
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Potential for Stem Cells Therapy in Alzheimer's Disease: Do Neurotrophic Factors Play Critical Role?
Published in Current Alzheimer research (01-01-2017)“…Alzheimer's disease (AD) is one of the most common causes of dementia. Despite several decades of research in AD, there is no standard disease- modifying…”
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Pharmacological antagonism of EP2 receptor does not modify basal cardiovascular and respiratory function, blood cell counts, and bone morphology in animal models
Published in Biomedicine & pharmacotherapy (01-03-2022)“…The EP2 receptor has emerged as a therapeutic target with exacerbating role in disease pathology for a variety of peripheral and central nervous system…”
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High glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells in vitro
Published in Scientific reports (24-09-2020)“…Maternal diabetes alters the global epigenetic mechanisms and expression of genes involved in neural tube development in mouse embryos. Since DNA methylation…”
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Characterization of lactic acid bacteria isolated from street pickles of Dhaka, Bangladesh
Published in Heliyon (01-06-2023)“…Traditionally fermented pickles are a popular street food in Bangladesh famous for their unique flavors and health benefits. Pickles are often prepared by…”
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CD34 and CD117 Stemness of Lineage-Negative Cells Reverses Memory Loss Induced by Amyloid Beta in Mouse Model
Published in Frontiers in behavioral neuroscience (01-11-2018)“…A majority of the neurodegenerative disorders including Alzheimer's disease are untreatable and occur primarily due to aging and rapidly changing lifestyles…”
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Comparative Phytochemical and Antibacterial Properties of Piper betle Leave Extracts from Barguna and Moheshkhali, Bangladesh
Published in Majallah-i mīkrub/shināsī-i pizishkī-i Īrān (01-03-2020)“…Objectives: Leaves of Piper betle are frequently used in South and Southeast Asia for traditional treatment and as a mouth freshener. Our purpose is to compare…”
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Loss of learning in mice when exposed to rat odor: A water maze study
Published in Behavioural brain research (2011)“…The study was designed to test the hypothesis if predator stress can affect learning in mice when exposed to rat odor. We investigated the spatial memory…”
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The animal models of dementia and Alzheimer's disease for pre-clinical testing and clinical translation
Published in Current Alzheimer research (01-11-2012)“…Dementia is a clinical syndrome with abnormal degree of memory loss and impaired ability to recall events from the past often characterized by Alzheimer's…”
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An enriched population of CD45, CD34 and CD117 stem cells in human umbilical cord blood for potential therapeutic regenerative strategies
Published in Current neurovascular research (01-01-2014)“…Human umbilical cord blood (hUCB) is a primitive source of stem cells and is being banked worldwide for the purpose of future clinical use. Lineage negative…”
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Neuroimmunometabolism: A New Pathological Nexus Underlying Neurodegenerative Disorders
Published in The Journal of neuroscience (09-03-2022)“…Neuroimmunometabolism is an emerging field that examines the intersection of immunologic and metabolic cascades in the brain. Neuroinflammatory conditions…”
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Peripherally Restricted, Highly Potent, Selective, Aqueous-Soluble EP2 Antagonist with Anti-Inflammatory Properties
Published in Molecular pharmaceutics (03-12-2018)“…The prostaglandin E2 receptor, EP2, plays an important role in physiology and in a variety of pathological conditions. Studies indicate that EP2 is…”
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Alteration of Neurotrophic Factors After Transplantation of Bone Marrow Derived Lin‐ve Stem Cell in NMDA‐Induced Mouse Model of Retinal Degeneration
Published in Journal of cellular biochemistry (01-07-2017)“…ABSTRACT Retinal ganglion cell layer (RGCs) is one of the important layers of retina, depleted in Glaucoma. Loss of RGC neurons is a major cellular mechanism…”
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One day CRIKC workshop on Technical Advances in Retinal Imaging
Published in Annals of Neurosciences (01-10-2015)“…It is heartening to mention here that the Chandigarh Region Innovation & Knowledge Cluster (CRIKC) is accelerating its programs to "promote and sustain…”
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Effect of human umbilical cord blood derived lineage negative stem cells transplanted in amyloid-β induced cognitive impaired mice
Published in Behavioural brain research (15-09-2015)“…•Umbilical cord blood derived Lin −ve stem cells alleviate amyloid-β induced behavioral deficits.•Lin −ve cells showed a time and dose specific spatial memory…”
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Maternal Factors that Induce Epigenetic Changes Contribute to Neurological Disorders in Offspring
Published in Genes (24-05-2017)“…It is well established that the regulation of epigenetic factors, including chromatic reorganization, histone modifications, DNA methylation, and miRNA…”
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Preclinical development of an EP2 antagonist for post-seizure cognitive deficits
Published in Neuropharmacology (15-02-2023)“…Cognitive comorbidities can substantially reduce quality of life in people with epilepsy. Inflammation is a component of all chronic diseases including…”
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Alpha lipoic acid attenuates the long-term effects of lead exposure in retinal ischemic injury mouse model
Published in Environmental science and pollution research international (01-05-2019)“…Lead (Pb) exposure is reported to be unsafe for humans. There have been several studies documenting acute and chronic Pb toxicity on the organ systems. New…”
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