Search Results - "Avgeris, Margaritis"
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1
Jagged Ends of Cell-Free DNA: Rebranding Fragmentomics in Modern Liquid Biopsy Diagnostics
Published in Clinical chemistry (Baltimore, Md.) (31-03-2021)Get full text
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The lysine‐specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer
Published in EMBO reports (01-03-2019)“…Genome‐wide studies in tumor cells have indicated that chromatin‐modifying proteins are commonly mutated in human cancers. The lysine‐specific…”
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3
A new tumor suppressor role for the Notch pathway in bladder cancer
Published in Nature medicine (01-10-2014)“…Rampias et al . report that inactivating mutations in Notch pathway components are frequent in human bladder cancer and drive bladder tumorigenesis in mice…”
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4
Evaluation of PD-L1 Expression and Associated Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma
Published in Clinical cancer research (01-02-2016)“…Programmed death-ligand 1 (PD-L1; also known as CD274 or B7-H1) expression represents a mechanism of immune escape for cancer. Our purpose was to characterize…”
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Loss of GAS5 tumour suppressor lncRNA: an independent molecular cancer biomarker for short-term relapse and progression in bladder cancer patients
Published in British journal of cancer (11-12-2018)“…Background Bladder cancer (BlCa) heterogeneity and the lack of personalised prognosis lead to patients’ highly variable treatment outcomes. Here, we have…”
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6
Circulating miR‐146a and miR‐134 in predicting drug‐resistant epilepsy in patients with focal impaired awareness seizures
Published in Epilepsia (Copenhagen) (01-05-2020)“…Objective Epilepsy is one of the most prevalent neurologic disorders, causing serious psychological problems and reducing quality of life. Although 20…”
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First Trimester Maternal Plasma Aberrant miRNA Expression Associated with Spontaneous Preterm Birth
Published in International journal of molecular sciences (29-11-2022)“…Spontaneous Preterm Delivery (sPTD) is one of the leading causes of perinatal mortality and morbidity worldwide. The present case−control study aims to detect…”
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8
miR‐181a overexpression predicts the poor treatment response and early‐progression of serous ovarian cancer patients
Published in International journal of cancer (15-12-2020)“…Ovarian cancer (OC) remains a leading cause of gynecological cancer‐related death worldwide, characterized by poor 5‐year survival. Molecular markers could…”
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Small RNA‐seq and clinical evaluation of tRNA‐derived fragments in multiple myeloma: Loss of mitochondrial i‐tRFHisGTG results in patients' poor treatment outcome
Published in British journal of haematology (01-05-2024)“…Despite the substantial progress in multiple myeloma (MM) therapy nowadays, treatment resistance and disease relapse remain major clinical hindrances. Herein,…”
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10
tRNAGlyGCC-Derived Internal Fragment (i-tRF-GlyGCC) in Ovarian Cancer Treatment Outcome and Progression
Published in Cancers (22-12-2021)“…Epithelial ovarian cancer (EOC) remains a highly-lethal gynecological malignancy, characterized by frequent recurrence, chemotherapy resistance and poor 5-year…”
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11
miRNA-Based Technologies in Cancer Therapy
Published in Journal of personalized medicine (01-11-2023)“…The discovery of therapeutic miRNAs is one of the most exciting challenges for pharmaceutical companies. Since the first miRNA was discovered in 1993, our…”
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12
Kallikrein-related peptidase genes as promising biomarkers for prognosis and monitoring of human malignancies
Published in Biological chemistry (01-05-2010)“…Tissue kallikrein (KLK1) and the kallikrein-related peptidase (KLK2-15) genes encode for a subgroup of 15 homologous secreted serine proteases possessing…”
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13
Epi‐miRNAs: Modern mediators of methylation status in human cancers
Published in Wiley interdisciplinary reviews. RNA (01-03-2023)“…Methylation of the fundamental macromolecules, DNA/RNA, and proteins, is remarkably abundant, evolutionarily conserved, and functionally significant in…”
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14
HPV16 E6/E7 expression in circulating tumor cells in oropharyngeal squamous cell cancers: A pilot study
Published in PloS one (09-05-2019)“…Human papillomavirus-related oropharyngeal squamous cell carcinoma (HPV+ OPSCC) is increasing in incidence. Although HPV+ OPSCC has favorable prognosis, 10 to…”
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miRNA-seq and clinical evaluation in multiple myeloma: miR-181a overexpression predicts short-term disease progression and poor post-treatment outcome
Published in British journal of cancer (01-01-2022)“…Background Despite significant advances in multiple myeloma (MM) therapy, disease relapse and treatment resistance remain major obstacles in clinical…”
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28S rRNA-Derived Fragments Represent an Independent Molecular Predictor of Short-Term Relapse in Prostate Cancer
Published in International journal of molecular sciences (23-12-2023)“…Prostate cancer (PCa) is a global health concern, being a leading cause of cancer-related mortality among males. Early detection and accurate prognosis are…”
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Deregulated Expression of IL-37 in Patients with Bladder Urothelial Cancer: The Diagnostic Potential of the IL-37e Isoform
Published in International journal of molecular sciences (25-05-2023)“…Cellular and molecular immune components play a crucial role in the development and perpetuation of human malignancies, shaping anti-tumor responses. A novel…”
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Clinical utility of miR-143/miR-182 levels in prognosis and risk stratification specificity of BFM-treated childhood acute lymphoblastic leukemia
Published in Annals of hematology (01-07-2018)“…Although childhood acute lymphoblastic leukemia (ALL) is characterized by high remission rates, there are still patients who experience poor response to…”
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Novel Nested-Seq Approach for SARS-CoV-2 Real-Time Epidemiology and In-Depth Mutational Profiling in Wastewater
Published in International journal of molecular sciences (07-08-2021)“…Considering the lack of effective treatments against COVID-19, wastewater-based epidemiology (WBE) is emerging as a cost-effective approach for real-time…”
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ΔNp63 transcript loss in bladder cancer constitutes an independent molecular predictor of TaT1 patients post-treatment relapse and progression
Published in Journal of cancer research and clinical oncology (01-12-2019)“…Purpose Bladder cancer represents a major cause of malignancy-related morbidity and the most expensive per -patient-to-treat cancer, due to the lifelong…”
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