Search Results - "Averlant‐Petit, Marie‐Christine"
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Consequences of Isostructural Main-Chain Modifications for the Design of Antimicrobial Foldamers: Helical Mimics of Host-Defense Peptides Based on a Heterogeneous Amide/Urea Backbone
Published in Angewandte Chemie (International ed.) (08-01-2010)“…Fraternal twins: Oligoureas and γ‐peptides are isosteric, quasi‐isostructural helical foldamers endowed with distinct biomolecular recognition properties…”
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Rheological investigation of supramolecular physical gels in water/dimethylsulfoxide mixtures by lysine derivatives
Published in Polymer international (01-03-2021)“…Two derivatives of lysine were synthesized by acylating the Nα with dodecanoic acid starting from commercial precursors in which the Nε was already acylated by…”
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Emerging low-molecular weight nucleopeptide-based hydrogels: state of the art, applications, challenges and perspectives
Published in Nanoscale (31-03-2022)“…Over the last twenty years, low-molecular weight gelators and, in particular, peptide-based hydrogels, have drawn great attention from scientists thanks to…”
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Helical Oligomers of Thiazole-Based γ-Amino Acids: Synthesis and Structural Studies
Published in Angewandte Chemie International Edition (03-06-2013)“…9‐Helix: 4‐Amino(methyl)‐1,3‐thiazole‐5‐carboxylic acids (ATCs) were synthesized as new γ‐amino acid building blocks. The structures of various ATC oligomers…”
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Robust Helix Formation in a New Family of Oligoureas Based on a Constrained Bicyclic Building Block
Published in Angewandte Chemie International Edition (05-11-2012)“…BAC for more: A constrained bicyclic building block with urea linkages is an efficient combination for the formation of a highly rigid helical system. This…”
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Synthesis and Structural Characterization of 2:1 [α/Aza]-oligomers
Published in European journal of organic chemistry (01-12-2014)“…The design of a new β‐turn inducer is correlated to the discovery of new foldamers. In this paper, we report the liquid phase synthesis of 2:1…”
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Highly Synergistic Properties of Multicomponent Hydrogels Thanks to Cooperative Nucleopeptide Assemblies
Published in Chemistry of materials (13-06-2023)“…Supramolecular materials have drawn much attention in the past years, particularly because of their great versatility in terms of structures, organization, and…”
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Improving and fine-tuning the properties of peptide-based hydrogels via incorporation of peptide nucleic acids
Published in Nanoscale (14-10-2020)“…Peptide self-assemblies have attracted intense research interest over the last few decades thanks to their implications in key biological processes (e.g.,…”
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Rheological investigation of the influence of dextran on the self-assembly of lysine derivatives in water/dimethylsulfoxide mixtures
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (20-09-2021)“…Hybrid molecular/macromolecular gels were formulated by mixing amino-acid based gelators with dextran, a nonionic bacterial polysaccharide, in mixtures of…”
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Both metal-chelating and free radical-scavenging synthetic pentapeptides as efficient inhibitors of reactive oxygen species generation
Published in Metallomics (01-08-2020)“…Reactive oxygen species (ROS) are major sources of oxidative stress playing prominent roles in the development of several pathologies including cardiovascular…”
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Cyclohexamer [-(-Phe-azaPhe-Ala)-]: good candidate to formulate supramolecular organogels
Published in RSC advances (07-12-2020)“…Molecular self-assembly is a fascinating process which has become an area of great interest in supramolecular chemistry, as it leads in certain cases to…”
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Unprecedented Chain-Length-Dependent Conformational Conversion Between 11/9 and 18/16 Helix in α/β-Hybrid Peptides
Published in Angewandte Chemie International Edition (24-11-2014)“…α,β‐Hybrid oligomers of varying lengths with alternating proteogenic α‐amino acid and the rigid β2,3,3‐trisubstituted bicyclic amino acid ABOC residues were…”
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Impact of Cα‐Chirality on Supramolecular Self‐Assembly in Cyclo‐2:1‐[α/aza]‐Hexamers (d/l‐Phe‐azaPhe‐Ala)2
Published in European journal of organic chemistry (01-09-2017)“…The design of new cyclic pseudopeptides of the sequence 2:1‐[α/aza]‐hexamers, which contain aza‐amino acid motifs, has gained much prominence to be involved in…”
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Mixed Oligoureas Based on Constrained Bicyclic and Acyclic β-Amino Acids Derivatives: On the Significance of the Subunit Configuration for Folding
Published in Chemistry : a European journal (09-12-2013)“…The combination of a non‐functionalized constrained bicyclo[2.2.2]octane motif along with urea linkages allowed the formation of a highly rigid 2.512/14…”
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Elaboration and structural studies of cyclo 1:1-[α/α-N-amino]mers
Published in Tetrahedron letters (24-09-2014)“…In order to investigate the ability of self-organization of the alternance of α-amino and α-N-amino-acids the synthesis of cyclo 1:1-[α/α-N-amino]mers has been…”
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Conformational studies of new pseudotripeptide with pyrazine amidoxime motif and simplified analogs using IR, NMR spectroscopy, and molecular dynamic simulations
Published in Structural chemistry (01-06-2017)“…Solution structures of new pyrazine-based pseudotripeptide with amidoxime function and simplified pseudodipeptide analogs were determined by a combination of…”
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Cyclic Enkephalins with a Diversely Substituted Guanidine Bridge or a Thiourea Bridge: Synthesis, Biological and Structural Evaluations
Published in Journal of medicinal chemistry (25-07-2013)“…Two series of 22 and 15 atom cyclic enkephalins incorporating a diversely substituted guanidine bridge have been prepared to assess the potential effect of the…”
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Noncationic Dipeptide Mimic Oligomers As Cell Penetrating Nonpeptides (CPNP)
Published in Bioconjugate chemistry (20-10-2010)“…Small oligomers of constrained dipeptide mimics have been synthesized as new vectors for intracellular delivery. They are highly internalized by cells and…”
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Molecular modeling study for a novel structured oligomer subunit selection: the example of 2-aminomethyl-phenyl-acetic acid
Published in Tetrahedron letters (05-03-2007)“…Oligomers derived from dipeptide mimics were selected by computational study for their suitability to fold in ordered structures. After selection of a…”
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Solution Structure and Dynamics of the Reduced and Oxidized Forms of the N-Terminal Domain of PilB from Neisseria meningitidis
Published in Biochemistry (Easton) (19-08-2008)“…The secreted form of the PilB protein was proposed to be involved in pathogen survival fighting against the defensive host’s oxidative burst. PilB protein is…”
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